Low brown adipose tissue activity in endurance-trained compared with lean sedentary men

• Published in: International Journal of Obesity Vol. 39; no. 12; pp. 1696 - 1702
• Main Authors: Vosselman, M J, Hoeks, J, Brans, B, Pallubinsky, H, Nascimento, E B M, van der Lans, A A J J, Broeders, E P M, Mottaghy, F M, Schrauwen, P, van Marken Lichtenbelt, W D
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.12.2015; Nature Publishing Group
• Subjects: 59/78; 631/443/319; 631/443/319/333/1465; 692/53; 692/699/2743/393; 82/80; Adipocytes; Adipose tissue; Adipose tissue (brown); Adipose Tissue, Brown - diagnostic imaging; Adipose Tissue, Brown - metabolism; Adipose tissues; Adult; Athletes; Biomarkers; Biomarkers - metabolism; Biopsy; Body composition; Body fat; Browning; Cold; Cold Temperature; Comparative analysis; Computed tomography; Cytokines; Diabetes; Epidemics; Epidemiology; Fatigue tests; Fibronectins - blood; Fluorine isotopes; Fluorodeoxyglucose F18 - metabolism; Gene expression; Gene Expression Regulation; Health Promotion and Disease Prevention; Humans; Interleukin 6; Interleukin-6 - blood; Internal Medicine; Male; Males; Medicine; Medicine & Public Health; Membrane proteins; Metabolic Diseases; Metabolism; Muscle, Skeletal - diagnostic imaging; Muscle, Skeletal - metabolism; Muscles; Musculoskeletal system; Nutrition; Obesity; Observations; original-article; Physical Endurance; Physical training; Physiological aspects; Positron emission; Positron emission tomography; Positron-Emission Tomography - methods; Proteins; Public Health; Radiopharmaceuticals; Recruitment; Sedentary behavior; Sedentary Lifestyle; Skeletal muscle; Thermogenesis; Thinness; Tomography; Tomography, X-Ray Computed; Netherlands

Background/objectives: It has now been unequivocally demonstrated that humans possess functional brown adipose tissue (BAT) and that human BAT can be recruited upon chronic cold stimulation. Recruitment of BAT has been postulated as a potential strategy to counteract the current global obesity epide...