Ghana: Accelerating neglected tropical disease control in a setting of economic development

According to the GBD 2017, schistosomiasis is the second most prevalent human helminth infection (following hookworm infection) in Ghana, affecting almost one million people [9]. [...]among the arbovirus infections, the incidence of dengue in Ghana and elsewhere in West Africa is believed to have ri...

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Published inPLoS neglected tropical diseases Vol. 13; no. 1; p. e0007005
Main Authors Hotez, Peter J., Biritwum, Nana-Kwadwo, Fenwick, Alan, Molyneux, David H., Sachs, Jeffrey D.
Format Journal Article
LanguageEnglish
Published United States Public Library of Science 01.01.2019
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Abstract According to the GBD 2017, schistosomiasis is the second most prevalent human helminth infection (following hookworm infection) in Ghana, affecting almost one million people [9]. [...]among the arbovirus infections, the incidence of dengue in Ghana and elsewhere in West Africa is believed to have risen precipitously. According to WHO, Ghana is one of 14 countries considered at high risk of yellow fever outbreaks, although it is not currently one of the four West African nations considered as a “complex emergency situation” [50]. The concerns about albendazole resistance and reduced ivermectin efficacy will also need to be addressed, with consideration of developing improved biotechnologies for some of the NTDs [51]. [...]we have seen how dengue and yellow fever can persist even in middle-income countries, so that for these diseases as well new technologies will need to be developed and implemented.
AbstractList According to the GBD 2017, schistosomiasis is the second most prevalent human helminth infection (following hookworm infection) in Ghana, affecting almost one million people [9]. [...]among the arbovirus infections, the incidence of dengue in Ghana and elsewhere in West Africa is believed to have risen precipitously. According to WHO, Ghana is one of 14 countries considered at high risk of yellow fever outbreaks, although it is not currently one of the four West African nations considered as a “complex emergency situation” [50]. The concerns about albendazole resistance and reduced ivermectin efficacy will also need to be addressed, with consideration of developing improved biotechnologies for some of the NTDs [51]. [...]we have seen how dengue and yellow fever can persist even in middle-income countries, so that for these diseases as well new technologies will need to be developed and implemented.
According to the GBD 2017, schistosomiasis is the second most prevalent human helminth infection (following hookworm infection) in Ghana, affecting almost one million people [9]. [...]among the arbovirus infections, the incidence of dengue in Ghana and elsewhere in West Africa is believed to have risen precipitously. According to WHO, Ghana is one of 14 countries considered at high risk of yellow fever outbreaks, although it is not currently one of the four West African nations considered as a “complex emergency situation” [50]. The concerns about albendazole resistance and reduced ivermectin efficacy will also need to be addressed, with consideration of developing improved biotechnologies for some of the NTDs [51]. [...]we have seen how dengue and yellow fever can persist even in middle-income countries, so that for these diseases as well new technologies will need to be developed and implemented.
Audience Academic
Author Sachs, Jeffrey D.
Molyneux, David H.
Hotez, Peter J.
Biritwum, Nana-Kwadwo
Fenwick, Alan
AuthorAffiliation 2 Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, Texas, United States of America
10 Center for Sustainable Development, Earth Institute, Columbia University, New York, New York, United States of America
1 Texas Children’s Hospital Center for Vaccine Development, Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America
6 Bill & Melinda Gates Foundation, Seattle, Washington, United States of America
4 James A Baker III Institute of Public Policy, Rice University, Houston, Texas, United States of America
9 Liverpool School of Tropical Medicine, Liverpool, United Kingdom
7 Ghana Health Service, Accra, Ghana
University of Nottingham, UNITED KINGDOM
5 Scowcroft Institute of International Affairs, Bush School of Government and Public Policy, Texas A&M University, College Station, Texas, United States of America
8 Department of Infectious Disease Epidem
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– name: 10 Center for Sustainable Development, Earth Institute, Columbia University, New York, New York, United States of America
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– name: 7 Ghana Health Service, Accra, Ghana
– name: 1 Texas Children’s Hospital Center for Vaccine Development, Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America
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PJH is lead investigator on several vaccines against neglected tropical diseases in development and in clinical trials.
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SubjectTerms Albendazole
Animals
Arbovirus Infections - epidemiology
Arbovirus Infections - prevention & control
Biology and Life Sciences
Biotechnology
Communicable Disease Control - methods
Control
Countries
Dengue
Dengue fever
Disease control
Disease transmission
Economic Development
Economic growth
Economics
Fever
Filariasis
Forecasts and trends
Ghana
Ghana - epidemiology
Growth rate
Helminthiasis - epidemiology
Helminthiasis - prevention & control
Human diseases
Humans
Infections
Ivermectin
Medicine
Medicine and Health Sciences
Neglected Diseases - epidemiology
Neglected Diseases - prevention & control
New technology
Onchocerciasis
Outbreaks
People and Places
Poverty
Public Health
Public policy
Risk factors
Schistosomiasis
Trachoma
Tropical climate
Tropical diseases
Tropical Medicine
Trypanosomiasis
Ulcers
Vector-borne diseases
Viewpoints
Viral diseases
Yellow fever
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Title Ghana: Accelerating neglected tropical disease control in a setting of economic development
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Volume 13
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