Connectivity reveals relationship of brain areas for reward-guided learning and decision making in human and monkey frontal cortex

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 112; no. 20; pp. E2695 - E2704
• Main Authors: Neubert, Franz-Xaver, Mars, Rogier B., Sallet, Jérôme, Rushworth, Matthew F. S.
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 19.05.2015; National Acad Sciences
• Series: PNAS Plus
• Subjects: Animal cognition; Animals; Biological Sciences; Brain; Connectome - methods; cortex; Decision making; Decision Making - physiology; foraging; Frontal Lobe - physiology; Human subjects; Humans; learning; Learning - physiology; Macaca; Macaca - physiology; Magnetic Resonance Imaging; Models, Neurological; monkeys; Monkeys & apes; Neurosciences; NMR; Nuclear magnetic resonance; PNAS Plus; Reward; Social Sciences; Species Specificity; comparative anatomy; orbitofrontal cortex; resting state functional connectivity; anterior cingulate cortex; decision making

Reward-guided decision-making depends on a network of brain regions. Among these are the orbitofrontal and the anterior cingulate cortex. However, it is difficult to ascertain if these areas constitute anatomical and functional unities, and how these areas correspond between monkeys and humans. To a...