DELLA protein functions as a transcriptional activator through the DNA binding of the INDETERMINATE DOMAIN family proteins

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 111; no. 21; pp. 7861 - 7866
• Main Authors: Yoshida, Hideki, Hirano, Ko, Sato, Tomomi, Mitsuda, Nobutaka, Nomoto, Mika, Maeo, Kenichiro, Koketsu, Eriko, Mitani, Rie, Kawamura, Mayuko, Ishiguro, Sumie, Tada, Yasuomi, Ohme-Takagi, Masaru, Matsuoka, Makoto, Ueguchi-Tanaka, Miyako
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 27.05.2014; National Acad Sciences
• Subjects: Arabidopsis; Arabidopsis - metabolism; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Arabidopsis Proteins - physiology; Biological Sciences; Co-Repressor Proteins - genetics; Co-Repressor Proteins - metabolism; Deoxyribonucleic acid; DNA; DNA Primers; DNA-binding domains; DNA-Binding Proteins - genetics; Gene expression; Gene expression regulation; Gene Expression Regulation, Plant - genetics; Gene Expression Regulation, Plant - physiology; Genes; Genotype & phenotype; Gibberellins; hybrids; luciferase; Phenotypes; Plant Proteins - metabolism; Plants; Promoter regions; Proteins; Protoplasts; signal transduction; transactivators; transcription (genetics); Transcription factors; Transcription Factors - metabolism; Transcriptional Activation - genetics; Transgenic plants; Two-Hybrid System Techniques; Yeasts; coactivator/corepressor exchange regulation system; transcription factor; gibberellin feedback regulation

DELLA protein is a key negative regulator of gibberellin (GA) signaling. Although how DELLA regulates downstream gene expression remains unclear, DELLA has been proposed to function as a transcriptional activator. However, because DELLA lacks a DNA-binding domain, intermediate protein(s) mediating t...