Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition - Yen, Hsin-Yung; Liu, Ying-Chih; Chen, Nai-Yu; Tsai, Chia-Feng; Wang, Yi-Ting; Chen, Yu-Ju; Hsu, Tsui-Ling; Yang, Pan-Chyr; Wong, Chi-Huey (Proceedings of the National Academy of Sciences - PNAS, 2015)
Keywords: Biological Sciences; carcinogenesis; Cell Line, Tumor; Cells; Dimerization; Enzyme Inhibitors; Epidermal growth factor; epidermal growth factor receptors; gene expression regulation; Humans; Kinases; Lung cancer; lung neoplasms; Models, Molecular; Mutation; Mutation, Missense - genetics; Neuraminidase - pharmacology; Phosphorylation; Phosphorylation - drug effects; Protein Binding - drug effects; Protein-Tyrosine Kinases - antagonists & inhibitors; Quinazolines; Receptor, Epidermal Growth Factor - genetics; Receptor, Epidermal Growth Factor - metabolism; tyrosine; lung cancer; dimerization; glycosylation; gefitinib; tyrosin kinase inhibitor