An in vivo genetic reversion highlights the crucial role of Myb-Like, SWIRM, and MPN domains 1 (MYSM1) in human hematopoiesis and lymphocyte differentiation - Le Guen, Tangui; Touzot, Fabien; André-Schmutz, Isabelle; Lagresle-Peyrou, Chantal; France, Benoit; Kermasson, Laetitia; Lambert, Nathalie; Picard, Capucine; Nitschke, Patrick; Carpentier, Wassila; Bole-Feysot, Christine; Lim, Annick; et al. (Journal of allergy and clinical immunology, 2015)
Keywords: Allergy and Immunology; B-Lymphocytes - cytology; Bone marrow; Cell Differentiation; Deoxyribonucleic acid; DNA; DNA methylation; DNA-Binding Proteins - genetics; Epigenetics; Gene expression; genetic reversion; Genomes; Hematopoiesis; Hematopoiesis - genetics; histone deubiquitinase; Humans; immunodeficiency; Immunoglobulins; Immunologic Deficiency Syndromes - genetics; Infant; Life Sciences; Lymphocytes; Lymphopenia - genetics; Male; Mutation; MYSM1; Proteins; Quality; Software; T-Lymphocytes - cytology; Thermal cycling; Transcription Factors - genetics; KO; MYSM1; genetic reversion; APC; Hematopoiesis; JAMM; PE; H2A; HSC; immunodeficiency; histone deubiquitinase; NK; WGHM; WT; JAB1/MPN/Mov34; Knockout; Wild-type; Histone 2A; Hematopoietic stem cell; Natural killer; Myb-Like, SWIRM, and MPN domains 1; Phycoerythrin; Allophycocyanin; Whole-genome homozygosity mapping