Achilles Tendon Ultrasonography for Diagnosis of Familial Hypercholesterolemia Among Japanese Subjects

• Published in: Circulation Journal Vol. 81; no. 12; pp. 1879 - 1885
• Main Authors: Michikura, Masahito, Ogura, Masatsune, Yamamoto, Masahiro, Sekimoto, Masahiko, Fuke, Chizuru, Hori, Mika, Arai, Koji, Kihara, Shinji, Hosoda, Kiminori, Yanagi, Koji, Harada-Shiba, Mariko
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Circulation Society 2017
• Subjects: Achilles tendon; Achilles Tendon - diagnostic imaging; Adult; Aged; Asian People; Carotid intima-media thickness; Coronary artery disease; Familial hypercholesterolemia; Female; Humans; Hyperlipoproteinemia Type II - diagnosis; Male; Middle Aged; Sensitivity and Specificity; Ultrasonography; Ultrasonography - methods; Achilles tendon; Familial hypercholesterolemia; Coronary artery disease; Carotid intima-media thickness; Ultrasonography

Background:Difficulty in detecting and measuring Achilles tendon (AT) xanthomas may be responsible for underdiagnosis of familial hypercholesterolemia (FH). We aimed to determine a cutoff value for AT thickness (AT-T) using ultrasonography to diagnose FH, and to investigate the relationship between...