Anesthesia and the Quantitative Evaluation of Neurovascular Coupling

• Published in: Journal of cerebral blood flow and metabolism Vol. 32; no. 7; pp. 1233 - 1247
• Main Authors: Masamoto, Kazuto, Kanno, Iwao
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.07.2012; Nature Publishing Group; Sage Publications Ltd
• Subjects: Anesthesia; Anesthesia - adverse effects; Anesthetics; Anesthetics - pharmacology; Animals; Attention; Biological and medical sciences; Blood-Brain Barrier - drug effects; Blood-Brain Barrier - physiology; Brain - drug effects; Brain - physiology; Cerebral blood flow; Cerebrovascular Circulation - drug effects; Cerebrovascular Circulation - physiology; Decision making; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Excitability; Hemodynamics - drug effects; Hemodynamics - physiology; Humans; Information processing; Medical sciences; Neuroimaging; Neurology; Neurotransmission; Review; Reviews; Vascular diseases and vascular malformations of the nervous system; Vasoactive agents; Vasodilation; animal models; awake experiments; neuroimaging; Animal model; Nervous system diseases; Central nervous system disease; Cerebrovascular disease; Cerebral disorder

Anesthesia has broad actions that include changing neuronal excitability, vascular reactivity, and other baseline physiologies and eventually modifies the neurovascular coupling relationship. Here, we review the effects of anesthesia on the spatial propagation, temporal dynamics, and quantitative re...