Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients - Takeda, Shuko; Commins, Caitlin; DeVos, Sarah L.; Nobuhara, Chloe K.; Wegmann, Susanne; Roe, Allyson D.; Costantino, Isabel; Fan, Zhanyun; Nicholls, Samantha B.; Sherman, Alexis E.; Trisini Lipsanopoulos, Ana T.; Scherzer, Clemens R.; et al. (Annals of neurology, 2016)
Keywords: Aged; Aggregates; Alzheimer Disease - cerebrospinal fluid; Alzheimer's disease; Animals; Biomarkers; Biomarkers - cerebrospinal fluid; Brain; Brain - metabolism; Cerebrospinal fluid; Extracellular Fluid - metabolism; Female; Health risk assessment; Humans; Male; Mice; Mice, Transgenic; Middle Aged; Molecular weight; Neurodegeneration; Neurodegenerative diseases; Rare species; Rodents; Tau protein; tau Proteins - cerebrospinal fluid; Transgenic mice; Ventricle