Overexpression of the FRO2 ferric chelate reductase confers tolerance to growth on low iron and uncovers posttranscriptional control

• Published in: Plant physiology (Bethesda) Vol. 133; no. 3; pp. 1102 - 1110
• Main Authors: Connolly, E.L, Campbell, N.H, Grotz, N, Prichard, C.L, Guerinot, M.L
• Format: Journal Article
• Language: English
• Published: Rockville, MD American Society of Plant Biologists 01.11.2003; American Society of Plant Physiologists; The American Society for Plant Biologists
• Subjects: Adaptation, Physiological; Adaptation, Physiological - drug effects; Adaptation, Physiological - genetics; Arabidopsis; Arabidopsis - enzymology; Arabidopsis - genetics; Arabidopsis - growth & development; Arabidopsis Proteins; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Arabidopsis thaliana; Biological and medical sciences; cadmium; Cation Transport Proteins; Cation Transport Proteins - genetics; Cation Transport Proteins - metabolism; Chelates; copper chelate reductase; drug effects; enzyme activity; enzymology; epidermis (plant); ferric chelate reductase; flowers; Flowers - enzymology; Flowers - genetics; FMN Reductase; FMN Reductase - genetics; FMN Reductase - metabolism; FR)2 protein; Fundamental and applied biological sciences. Psychology; Gene expression regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; gene overexpression; genetics; Genetics, Genomics, and Molecular Evolution; growth & development; Iron; Iron - pharmacology; irt 1 protein; Messenger RNA; metabolism; Molecular Sequence Data; NADH or NADPH oxidoreductases; nucleotide sequences; pharmacology; Plant Epidermis; Plant Epidermis - enzymology; Plant Epidermis - genetics; Plant growth regulators; Plant physiology and development; plant proteins; plant response; Plant Roots; Plant Roots - enzymology; Plant Roots - genetics; plant stress; Plants; post-transcriptional RNA processing; RNA; RNA Processing, Post-Transcriptional; RNA Processing, Post-Transcriptional - drug effects; roots; transcription (genetics); Transgenic plants; transporters; Water and solutes. Absorption, translocation and permeability; Zinc; Zinc - pharmacology; Growth; Available nutrient; Gene overexpression; Iron; Inorganic element; Posttranscriptional modification; Arabidopsis thaliana; Regulation(control); Absorption; Cruciferae; Dicotyledones; Angiospermae; Carrier protein; Adaptation; Cadmium; Starvation; Nutrition; Enzyme; Deficiency; Tolerance; Nutrient uptake; Zinc; Heavy metal; Ferric-chelate reductase; Nutrient; Spermatophyta; Oxidoreductases; Experimental plant

The Arabidopsis FRO2 gene encodes the low-iron-inducible ferric chelate reductase responsible for reduction of iron at the root surface. Here, we report that FRO2 and IRT1, the major transporter responsible for high-affinity iron uptake from the soil, are coordinately regulated at both the transcrip...