Therapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials

Punica granatum L. belongs to the Punicaceae family which is distributed around the world. Different parts of pomegranate like seed, peel, juice, and leaves are rich in potential bioactive compounds. These plants have found application in traditional medicine such as in treatment of gastrointestinal...

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Published inJournal of nutrition and metabolism Vol. 2021; pp. 1 - 22
Main Authors Eghbali, Samira, Askari, Sayyedeh Fatemeh, Avan, Razieh, Sahebkar, Amirhossein
Format Journal Article
LanguageEnglish
Published New York Hindawi 2021
John Wiley & Sons, Inc
Wiley
Subjects
Acids
Arthritis
Bioactive compounds
Cardiovascular diseases
Clinical trials
COVID-19
diabetes
Diabetes mellitus
Drug development
Endocrine disorders
Flavonoids
Fruits
gastrointestinal system
Health aspects
Isoflavones
juices
lignans
Medicinal plants
metabolism
mouth
nutrition
Oral cavity
Polycystic ovary syndrome
Polyphenols
pomegranates
Punica granatum
Review
Reviews
Saponins
Seeds
therapeutics
Traditional medicine
Triterpenes
triterpenoids
Womens health
Iran
Online AccessGet full text
ISSN2090-0724
2090-0732
2090-0732
DOI10.1155/2021/5297162

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Abstract Punica granatum L. belongs to the Punicaceae family which is distributed around the world. Different parts of pomegranate like seed, peel, juice, and leaves are rich in potential bioactive compounds. These plants have found application in traditional medicine such as in treatment of gastrointestinal, cardiovascular, and endocrine diseases, among others. The present review aimed to summarize the current research on the traditional and scientific applications of P. granatum with regard to the phytochemical content and clinical applications that may be useful for future drug development. Information about P. granatum was obtained from local classic herbal literature and electronic databases, such as PubMed, Scopus, and ScienceDirect. Several phytochemical constituents including polyphenolics, flavonoids, anthocyanosides, alkaloids, lignans, and triterpenes have been reported from the plant. Randomized clinical trials have provided evidence as to the pharmacological activities of pomegranate in several diseases including diabetes, cardiovascular disease, oral cavity disorders, endocrine disorders, and cancer. The present review has provided an insight into the traditional applications of the plants, and some of them have been validated by scientific evidence, particularly their applications as treatment of cardiovascular and endocrine diseases.
AbstractList Punica granatum L. belongs to the Punicaceae family which is distributed around the world. Different parts of pomegranate like seed, peel, juice, and leaves are rich in potential bioactive compounds. These plants have found application in traditional medicine such as in treatment of gastrointestinal, cardiovascular, and endocrine diseases, among others. The present review aimed to summarize the current research on the traditional and scientific applications of P. granatum with regard to the phytochemical content and clinical applications that may be useful for future drug development. Information about P. granatum was obtained from local classic herbal literature and electronic databases, such as PubMed, Scopus, and ScienceDirect. Several phytochemical constituents including polyphenolics, flavonoids, anthocyanosides, alkaloids, lignans, and triterpenes have been reported from the plant. Randomized clinical trials have provided evidence as to the pharmacological activities of pomegranate in several diseases including diabetes, cardiovascular disease, oral cavity disorders, endocrine disorders, and cancer. The present review has provided an insight into the traditional applications of the plants, and some of them have been validated by scientific evidence, particularly their applications as treatment of cardiovascular and endocrine diseases.
Punica granatum L. belongs to the Punicaceae family which is distributed around the world. Different parts of pomegranate like seed, peel, juice, and leaves are rich in potential bioactive compounds. These plants have found application in traditional medicine such as in treatment of gastrointestinal, cardiovascular, and endocrine diseases, among others. The present review aimed to summarize the current research on the traditional and scientific applications of P. granatum with regard to the phytochemical content and clinical applications that may be useful for future drug development. Information about P. granatum was obtained from local classic herbal literature and electronic databases, such as PubMed, Scopus, and ScienceDirect. Several phytochemical constituents including polyphenolics, flavonoids, anthocyanosides, alkaloids, lignans, and triterpenes have been reported from the plant. Randomized clinical trials have provided evidence as to the pharmacological activities of pomegranate in several diseases including diabetes, cardiovascular disease, oral cavity disorders, endocrine disorders, and cancer. The present review has provided an insight into the traditional applications of the plants, and some of them have been validated by scientific evidence, particularly their applications as treatment of cardiovascular and endocrine diseases.
Punica granatum L. belongs to the Punicaceae family which is distributed around the world. Different parts of pomegranate like seed, peel, juice, and leaves are rich in potential bioactive compounds. These plants have found application in traditional medicine such as in treatment of gastrointestinal, cardiovascular, and endocrine diseases, among others. The present review aimed to summarize the current research on the traditional and scientific applications of P. granatum with regard to the phytochemical content and clinical applications that may be useful for future drug development. Information about P. granatum was obtained from local classic herbal literature and electronic databases, such as PubMed, Scopus, and ScienceDirect. Several phytochemical constituents including polyphenolics, flavonoids, anthocyanosides, alkaloids, lignans, and triterpenes have been reported from the plant. Randomized clinical trials have provided evidence as to the pharmacological activities of pomegranate in several diseases including diabetes, cardiovascular disease, oral cavity disorders, endocrine disorders, and cancer. The present review has provided an insight into the traditional applications of the plants, and some of them have been validated by scientific evidence, particularly their applications as treatment of cardiovascular and endocrine diseases.Punica granatum L. belongs to the Punicaceae family which is distributed around the world. Different parts of pomegranate like seed, peel, juice, and leaves are rich in potential bioactive compounds. These plants have found application in traditional medicine such as in treatment of gastrointestinal, cardiovascular, and endocrine diseases, among others. The present review aimed to summarize the current research on the traditional and scientific applications of P. granatum with regard to the phytochemical content and clinical applications that may be useful for future drug development. Information about P. granatum was obtained from local classic herbal literature and electronic databases, such as PubMed, Scopus, and ScienceDirect. Several phytochemical constituents including polyphenolics, flavonoids, anthocyanosides, alkaloids, lignans, and triterpenes have been reported from the plant. Randomized clinical trials have provided evidence as to the pharmacological activities of pomegranate in several diseases including diabetes, cardiovascular disease, oral cavity disorders, endocrine disorders, and cancer. The present review has provided an insight into the traditional applications of the plants, and some of them have been validated by scientific evidence, particularly their applications as treatment of cardiovascular and endocrine diseases.
Audience Academic
Author Askari, Sayyedeh Fatemeh
Sahebkar, Amirhossein
Avan, Razieh
Eghbali, Samira
AuthorAffiliation 7 School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
5 Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
3 Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran
1 Department of Pharmacognosy, School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran
6 Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
4 Department of Clinical Pharmacy, Medical Toxicology and Drug Abuse Research Center (MTDRC), School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran
2 Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
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– name: 7 School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
– name: 1 Department of Pharmacognosy, School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran
– name: 2 Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
– name: 3 Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran
– name: 5 Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
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  orcidid: 0000-0002-6412-5596
  surname: Avan
  fullname: Avan, Razieh
  organization: Department of Clinical PharmacyMedical Toxicology and Drug Abuse Research Center (MTDRC)School of PharmacyBirjand University of Medical SciencesBirjandIranbums.ac.ir
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  givenname: Amirhossein
  orcidid: 0000-0002-8656-1444
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  organization: Applied Biomedical Research CenterMashhad University of Medical SciencesMashhadIranmums.ac.ir
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Cites_doi 10.5005/jp-journals-10024-2617
10.1016/s0021-9150(01)00412-9
10.1007/s43440-020-00152-9
10.1186/s13063-019-3321-8
10.1016/j.jff.2019.103692
10.1016/j.nutres.2013.04.004
10.4103/2348-2915.200016
10.1177/2156587215598039
10.1007/s00240-014-0686-8
10.1002/mnfr.201500357
10.4103/0975-9476.96525
10.3390/foods9020122
10.1155/2015/938475
10.5812/ijem.33835
10.1017/s0007114513002407
10.1002/jsfa.10096
10.1177/2156587216633370
10.1002/mnfr.201800160
10.1016/j.amjcard.2009.05.037
10.1111/j.1572-0241.2006.00576.x
10.5812/ircmj.13542
10.1080/1028415x.2018.1436413
10.1016/j.jacc.2016.02.071
10.30476/dentjods.2019.44913
10.1142/s0192415x05003120
10.2174/1566524019666191129104153
10.1002/jcp.28561
10.1089/jmf.2004.7.305
10.7860/jcdr/2017/31035.10845
10.1002/jsfa.7977
10.1021/jf071689v
10.4034/pboci.2015.151.32
10.1111/j.1463-1326.2009.01132.x
10.1016/j.numecd.2018.07.002
10.7150/jca.7123
10.1016/j.freeradbiomed.2012.05.013
10.1053/j.jrn.2014.07.006
10.3177/jnsv.52.383
10.17795/jjnpp-21517
10.1016/j.clnu.2003.10.002
10.3390/foods10030657
10.1016/j.atherosclerosis.2013.11.037
10.1016/j.eururo.2004.12.001
10.2174/1381612823666170215104101
10.5958/0973-9130.2019.00062.8
10.1080/09637486.2019.1607831
10.5005/jp-journals-10024-1779
10.1016/s0889-1575(02)91071-9
10.1024/0300-9831/a000292
10.1039/c7fo01435j
10.1016/j.sjbs.2020.04.045
10.3390/molecules26041054
10.1158/1940-6207.capr-12-0423
10.3390/molecules26082385
10.1371/journal.pone.0219596
10.1016/j.nutres.2013.03.003
10.1016/j.ejphar.2020.173530
10.1017/s0007114510000504
10.1046/j.1439-0507.2003.00884.x
10.1371/journal.pone.0108532
10.4103/jmau.jmau_6_19
10.1155/2019/1269341
10.1038/ejcn.2016.151
10.1093/ecam/nel101
10.1016/j.sbspro.2010.03.073
10.5114/pdia.2014.47117
10.1016/j.eujim.2016.06.010
10.1089/jmf.2014.0103
10.1021/jf801756x
10.1002/ptr.4977
10.5897/JMPR11.577
10.1038/s41598-019-50926-2
10.1186/1475-2891-13-18
10.1002/mnfr.200900152
10.4103/2231-0754.115776
10.1016/j.foodchem.2005.03.010
10.1038/sj.ijir.3901570
10.1039/c6fo01616b
10.1097/gme.0b013e3182345b2f
10.1111/j.1460-9592.2008.02462.x
10.2478/cipms-2019-0021
10.1590/bjft.2014.008
10.4103/2008-7802.194883
10.1007/s11130-012-0295-z
10.1089/met.2017.0146
10.2147/dddt.s128470
10.3390/molecules21081059
10.1017/jns.2012.10
10.1021/jf203598m
10.1155/2013/708381
10.7326/0003-4819-145-12-200612190-00003
10.4103/0974-8520.190702
10.1186/s13063-021-05194-9
10.1039/c8fo00264a
10.1007/s11130-017-0605-6
10.21474/ijar01/440
10.3906/biy-2001-5
10.1007/s12070-018-1297-4
10.1038/pcan.2012.20
10.1016/j.imr.2014.03.001
10.1016/j.jff.2014.03.028
10.1080/09637486.2016.1229760
10.3109/09637486.2011.631521
10.1590/s1678-77572006000300003
10.1002/ptr.5643
10.1002/jsfa.6328
10.3390/molecules22101606
10.1016/j.amjcard.2005.05.026
10.1007/bf03346565
10.1155/2013/932401
10.3390/nu13082577
10.1038/pcan.2015.32
10.2174/1381612825666190708183941
10.1016/j.ctcp.2015.03.001
10.1002/mnfr.201300931
10.1159/000330116
10.1038/sj.ejcn.1602309
10.1016/j.ctcp.2015.12.003
10.1002/ptr.2759
10.1016/j.nutres.2014.08.003
10.1007/s40618-019-01139-x
10.1021/np0498051
10.4103/2279-042X.117389
10.3402/fnr.v59.28551
10.1016/j.atherosclerosis.2005.09.006
10.1007/s43440-020-00112-3
10.1002/ptr.5901
10.4103/0972-124x.138678
10.1002/jsfa.7647
10.1016/j.ctcp.2013.08.002
10.1186/2251-6581-11-11
10.1080/j157v06n02_07
10.1016/j.ctim.2016.04.002
10.1016/j.nut.2009.05.003
10.1007/s10600-010-9568-7
10.1017/S1047951109990850
10.1016/j.phytochem.2020.112619
10.3389/fphar.2018.00544
10.1016/j.jnutbio.2017.01.014
10.1016/j.clnesp.2018.11.013
ContentType Journal Article
Copyright Copyright © 2021 Samira Eghbali et al.
COPYRIGHT 2021 John Wiley & Sons, Inc.
Copyright © 2021 Samira Eghbali et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0
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References 88
89
M. A. Nuñez‐Sánchez (109) 2015; 59
H. Neuhöfer (30) 1993; 48
J. Sastry (58) 2017; 16
110
S. Asgary (120) 2013; 9
111
113
114
115
116
90
117
91
118
92
119
93
94
95
96
97
S. M. Mohammad (8) 2012; 6
10
98
11
99
12
13
14
H. Memarzadeh (42) 2015; 6
15
16
17
R. Kelishadi (132) 2011; 16
19
S. Babaeian (102) 2013; 13
121
1
122
123
4
125
5
126
6
127
128
A. A. Rashidi (84) 2013; 15
129
9
J. C. Deepak (157) 2018; 20
20
A. Zargaran (3) 2016; 1
23
S. J. Bhadbhade (163) 2011; 42
24
26
27
28
29
G. Sastravaha (172) 2005; 7
130
A. f. Mosa (22) 2021
135
136
137
138
139
F. Sadegh Eghbali (133) 2016; 19
31
32
34
36
37
38
39
140
142
143
144
145
146
147
148
40
43
44
45
46
P. Mishra (151) 2019; 20
48
49
F. Askari (18) 2020; 7
150
A. Konić‐Ristić (134) 2013; 93
A. González‐Sarrías (112) 2010; 54
153
154
155
156
158
159
M. Kamali (64) 2017; 19
J. Hsu (67) 2007; 6
51
52
53
54
55
56
57
59
S. Wahab (33) 1998; 36
160
161
A. González‐Sarrías (141) 2018; 62
162
M. Abidov (124) 2006; 140
164
165
166
167
168
E. Hekmatian (149) 2011; 7
169
60
61
62
E. Emanuele (66) 2017; 38
63
S. F. Askari (7) 2018; 3
65
A. Balbir-Gurman (47) 2011; 13
A. Eghdami (81) 2011; 5
68
69
J. S. Jurenka (2) 2008; 13
170
G. Sastravaha (171) 2003; 5
M. Grabež (100) 2020; 64
70
71
72
S. El-Toumy (25) 2001; 56
73
74
M. A. Nuñez‐Sánchez (107) 2014; 58
M. Srilekha (152) 2018; 10
75
76
77
A. Goshtasebi (41) 2015; 29
78
79
A. Alkhatib (21) 2021; 6
G. Sohrab (85) 2014; 19
101
103
R. Wang (35) 2010; 4
M. Rafraf (50) 2017; 19
104
105
106
80
108
82
83
86
87
M. Jazi (131) 2010; 20
References_xml – volume: 20
  start-page: 920
  year: 2019
  ident: 151
  article-title: Comparison of punica granatum, Terminalia chebula, and Vitis vinifera seed extracts used as mouthrinse on salivary Streptococcus mutans levels in children
  publication-title: The Journal of Contemporary Dental Practice
  doi: 10.5005/jp-journals-10024-2617
– volume: 20
  start-page: 110
  year: 2018
  ident: 157
  article-title: Effectiveness of pomegranate mouthrinse in reducing bacterial plaque, gingival inflammation and total salivary proteins over a period of 90 days: a double-blind randomized trial
  publication-title: Journal of the International Academy of Periodontology
– ident: 118
  doi: 10.1016/s0021-9150(01)00412-9
– ident: 19
  doi: 10.1007/s43440-020-00152-9
– ident: 62
  doi: 10.1186/s13063-019-3321-8
– volume: 64
  year: 2020
  ident: 100
  article-title: Beneficial effects of pomegranate peel extract on plasma lipid profile, fatty acids levels and blood pressure in patients with diabetes mellitus type-2: a randomized, double-blind, placebo-controlled study
  publication-title: Journal of Functional Foods
  doi: 10.1016/j.jff.2019.103692
– ident: 53
  doi: 10.1016/j.nutres.2013.04.004
– volume: 13
  start-page: 128
  year: 2008
  ident: 2
  article-title: Therapeutic applications of pomegranate (Punica granatum L.): a review
  publication-title: Alternative Medicine Review: A Journal of Clinical Therapeutic
– ident: 159
  doi: 10.4103/2348-2915.200016
– ident: 1
  doi: 10.1177/2156587215598039
– ident: 51
  doi: 10.1007/s00240-014-0686-8
– volume: 140
  start-page: 78
  year: 2006
  ident: 124
  article-title: Efficiency of pharmacologically-active antioxidant phytomedicine radical fruits in treatment hypercholesteremia at men
  publication-title: Georgian Medical News
– volume: 59
  start-page: 1973
  year: 2015
  ident: 109
  article-title: MicroRNAs expression in normal and malignant colon tissues as biomarkers of colorectal cancer and in response to pomegranate extracts consumption: critical issues to discern between modulatory effects and potential artefacts
  publication-title: Molecular Nutrition & Food Research
  doi: 10.1002/mnfr.201500357
– ident: 164
  doi: 10.4103/0975-9476.96525
– volume: 1
  start-page: 52
  year: 2016
  ident: 3
  article-title: Avicenna’s contribution to use meats in cardiovascular diseases
  publication-title: Traditional and Integrative Medicine
– ident: 4
  doi: 10.3390/foods9020122
– ident: 12
  doi: 10.1155/2015/938475
– volume: 6
  start-page: 1
  year: 2021
  ident: 21
  article-title: The use of fresh pomegranate juice in the treatment of COVID-19: clinical case study
  publication-title: PSM Biological Research
– volume: 3
  start-page: 223
  year: 2018
  ident: 7
  article-title: A brief review on vaginal drug delivery in traditional Persian medicine
  publication-title: Traditional and Integrative Medicine
– ident: 86
  doi: 10.5812/ijem.33835
– ident: 143
  doi: 10.1017/s0007114513002407
– ident: 57
  doi: 10.1002/jsfa.10096
– ident: 161
  doi: 10.1177/2156587216633370
– volume: 62
  year: 2018
  ident: 141
  article-title: The endotoxemia marker lipopolysaccharide‐binding protein is reduced in overweight‐obese subjects consuming pomegranate extract by modulating the gut microbiota: a randomized clinical trial
  publication-title: Molecular Nutrition & Food Research
  doi: 10.1002/mnfr.201800160
– ident: 137
  doi: 10.1016/j.amjcard.2009.05.037
– ident: 61
  doi: 10.1111/j.1572-0241.2006.00576.x
– ident: 59
  doi: 10.5812/ircmj.13542
– ident: 77
  doi: 10.1080/1028415x.2018.1436413
– volume: 5
  start-page: 2282
  year: 2011
  ident: 81
  article-title: Determination of antioxidant activity of juice and peel extract of three variety of pomegranate and clinical study
  publication-title: Advances in Environmental Biology
– ident: 123
  doi: 10.1016/j.jacc.2016.02.071
– ident: 166
  doi: 10.30476/dentjods.2019.44913
– ident: 73
  doi: 10.1142/s0192415x05003120
– volume: 19
  year: 2017
  ident: 64
  article-title: The role of syndrome differentiation in the clinical efficacy of Punica granatum on patients with ulcerative colitis
  publication-title: Iranian Red Crescent Medical Journal
– ident: 103
  doi: 10.2174/1566524019666191129104153
– volume: 19
  start-page: 215
  year: 2014
  ident: 85
  article-title: Effects of pomegranate juice consumption on inflammatory markers in patients with type 2 diabetes: a randomized, placebo-controlled trial
  publication-title: Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences
– ident: 89
  doi: 10.1002/jcp.28561
– ident: 98
  doi: 10.1089/jmf.2004.7.305
– ident: 165
  doi: 10.7860/jcdr/2017/31035.10845
– ident: 130
  doi: 10.1002/jsfa.7977
– ident: 142
  doi: 10.1021/jf071689v
– ident: 153
  doi: 10.4034/pboci.2015.151.32
– ident: 40
  doi: 10.1111/j.1463-1326.2009.01132.x
– ident: 43
  doi: 10.1016/j.numecd.2018.07.002
– ident: 113
  doi: 10.7150/jca.7123
– ident: 52
  doi: 10.1016/j.freeradbiomed.2012.05.013
– ident: 55
  doi: 10.1053/j.jrn.2014.07.006
– ident: 68
  doi: 10.3177/jnsv.52.383
– ident: 74
  doi: 10.17795/jjnpp-21517
– ident: 136
  doi: 10.1016/j.clnu.2003.10.002
– ident: 5
  doi: 10.3390/foods10030657
– ident: 128
  doi: 10.1016/j.atherosclerosis.2013.11.037
– ident: 111
  doi: 10.1016/j.eururo.2004.12.001
– volume: 7
  start-page: 70
  year: 2005
  ident: 172
  article-title: Adjunctive periodontal treatment with Centella asiatica and Punica granatum extracts in supportive periodontal therapy
  publication-title: Journal of the International Academy of Periodontology
– ident: 117
  doi: 10.2174/1381612823666170215104101
– ident: 71
  doi: 10.5958/0973-9130.2019.00062.8
– ident: 145
  doi: 10.1080/09637486.2019.1607831
– ident: 150
  doi: 10.5005/jp-journals-10024-1779
– ident: 31
  doi: 10.1016/s0889-1575(02)91071-9
– ident: 39
  doi: 10.1024/0300-9831/a000292
– ident: 13
  doi: 10.1039/c7fo01435j
– ident: 10
  doi: 10.1016/j.sjbs.2020.04.045
– ident: 11
  doi: 10.3390/molecules26041054
– ident: 116
  doi: 10.1158/1940-6207.capr-12-0423
– ident: 6
  doi: 10.3390/molecules26082385
– volume: 6
  start-page: 18
  year: 2015
  ident: 42
  article-title: Evaluation of efficacy of Punica granatum L. (Persian gulnar) on uterine leiomyoma related menorrhagia
  publication-title: International Journal of Biosciences
– ident: 78
  doi: 10.1371/journal.pone.0219596
– ident: 83
  doi: 10.1016/j.nutres.2013.03.003
– ident: 20
  doi: 10.1016/j.ejphar.2020.173530
– volume: 38
  start-page: 38
  year: 2017
  ident: 66
  article-title: Comparative effects of a fixed Polypodium leucotomos/pomegranate combination versus Polypodium leucotomos alone on skin biophysical parameters
  publication-title: Neuroendocrinology Letters
– volume: 9
  start-page: 326
  year: 2013
  ident: 120
  article-title: Clinical investigation of the acute effects of pomegranate juice on blood pressure and endothelial function in hypertensive individuals
  publication-title: ARYA Atherosclerosis
– volume: 29
  start-page: 199
  year: 2015
  ident: 41
  article-title: Anti-hemorrhagic activity of Punica granatum L. flower (Persian golnar) against heavy menstrual bleeding of endometrial origin: a double-blind, randomized controlled trial
  publication-title: Medical Journal of the Islamic Republic of Iran
– ident: 126
  doi: 10.1017/s0007114510000504
– ident: 170
  doi: 10.1046/j.1439-0507.2003.00884.x
– ident: 38
  doi: 10.1371/journal.pone.0108532
– ident: 9
  doi: 10.4103/jmau.jmau_6_19
– ident: 104
  doi: 10.1155/2019/1269341
– ident: 48
  doi: 10.1038/ejcn.2016.151
– ident: 80
  doi: 10.1093/ecam/nel101
– ident: 125
  doi: 10.1016/j.sbspro.2010.03.073
– ident: 69
  doi: 10.5114/pdia.2014.47117
– ident: 140
  doi: 10.1016/j.eujim.2016.06.010
– ident: 56
  doi: 10.1089/jmf.2014.0103
– ident: 88
  doi: 10.1021/jf801756x
– ident: 119
  doi: 10.1002/ptr.4977
– volume: 6
  start-page: 5306
  year: 2012
  ident: 8
  article-title: Chemical composition of the plant Punica granatum L. (pomegranate) and its effect on heart and cancer
  publication-title: Journal of Medicinal Plants Research
  doi: 10.5897/JMPR11.577
– ident: 70
  doi: 10.1038/s41598-019-50926-2
– volume-title: Potential Effect of Pomegranate Peels Extract (Punica granatum) against COVID-19 Virus
  year: 2021
  ident: 22
– ident: 54
  doi: 10.1186/1475-2891-13-18
– volume: 54
  start-page: 311
  year: 2010
  ident: 112
  article-title: Occurrence of urolithins, gut microbiota ellagic acid metabolites and proliferation markers expression response in the human prostate gland upon consumption of walnuts and pomegranate juice
  publication-title: Molecular Nutrition & Food Research
  doi: 10.1002/mnfr.200900152
– ident: 160
  doi: 10.4103/2231-0754.115776
– ident: 34
  doi: 10.1016/j.foodchem.2005.03.010
– ident: 36
  doi: 10.1038/sj.ijir.3901570
– ident: 37
  doi: 10.1039/c6fo01616b
– ident: 46
  doi: 10.1097/gme.0b013e3182345b2f
– volume: 19
  start-page: 16
  year: 2016
  ident: 133
  article-title: Effect of eight weeks of combined training exercise with and without pomegranate concentrate consumption on metabolic syndrome indexes in obese and overweight middle-aged women
  publication-title: The Iranian Journal of Obstetrics, Gynecology and Infertility
– volume: 13
  start-page: 7
  year: 2013
  ident: 102
  article-title: The effect of unsweetened pomegranate juice on insulin resistance, high sensitivity c-reactive protein and obesity among type 2 diabetes patients
  publication-title: Journal of Ardabil University of Medical Sciences
– ident: 76
  doi: 10.1111/j.1460-9592.2008.02462.x
– ident: 168
  doi: 10.2478/cipms-2019-0021
– volume: 7
  start-page: 229
  year: 2011
  ident: 149
  article-title: Effect of pomegranate peel extract lozenge on gag reflex in dental patients
  publication-title: Journal of Isfahan Dental School
– ident: 28
  doi: 10.1590/bjft.2014.008
– volume: 36
  year: 1998
  ident: 33
  article-title: Characterization of certain steroid hormones in Punica granatum L. seeds
  publication-title: Bulletin of Faculty of Pharmacy (Cairo University)
– ident: 87
  doi: 10.4103/2008-7802.194883
– ident: 121
  doi: 10.1007/s11130-012-0295-z
– volume: 10
  year: 2018
  ident: 152
  article-title: Comparing the antimicrobial effectiveness of Punica granatum and chlorhexidine-containing mouthwash: a single-blind randomized clinical trial
  publication-title: Drug Invention Today
– ident: 97
  doi: 10.1089/met.2017.0146
– ident: 65
  doi: 10.2147/dddt.s128470
– ident: 72
  doi: 10.3390/molecules21081059
– ident: 122
  doi: 10.1017/jns.2012.10
– volume: 4
  start-page: 77
  year: 2010
  ident: 35
  article-title: Pomegranate: constituents, bioactivities and pharmacokinetics
  publication-title: Fruit, Vegetable and Cereal Science and Biotechnology
– ident: 32
  doi: 10.1021/jf203598m
– ident: 93
  doi: 10.1155/2013/708381
– ident: 45
  doi: 10.7326/0003-4819-145-12-200612190-00003
– volume: 19
  year: 2017
  ident: 50
  article-title: Pomegranate (Punica granatum L.) peel hydroalcoholic extract supplementation reduces pain and improves clinical symptoms of knee osteoarthritis: a randomized double-blind placebo controlled study
  publication-title: Iranian Red Crescent Medical Journal
– ident: 162
  doi: 10.4103/0974-8520.190702
– volume: 15
  year: 2013
  ident: 84
  article-title: Effect of concentrated pomegranate juice consumption on glucose and lipid profile concentrations in type 2 diabetic patients
  publication-title: Zahedan Journal of Research in Medical Sciences
– ident: 23
  doi: 10.1186/s13063-021-05194-9
– ident: 110
  doi: 10.1039/c8fo00264a
– ident: 129
  doi: 10.1007/s11130-017-0605-6
– volume: 56
  start-page: 823
  year: 2001
  ident: 25
  article-title: Ellagi-and gallotannins from Punica granatum heartwood
  publication-title: Die Pharmazie
– ident: 82
  doi: 10.21474/ijar01/440
– ident: 14
  doi: 10.3906/biy-2001-5
– ident: 106
  doi: 10.1007/s12070-018-1297-4
– ident: 115
  doi: 10.1038/pcan.2012.20
– ident: 169
  doi: 10.1016/j.imr.2014.03.001
– ident: 147
  doi: 10.1016/j.jff.2014.03.028
– volume: 48
  start-page: 389
  year: 1993
  ident: 30
  article-title: Alkaloids in the bark of Punica granatum L. (pomegranate) from Yugoslavia
  publication-title: Die Pharmazie
– volume: 5
  start-page: 106
  year: 2003
  ident: 171
  article-title: Adjunctive periodontal treatment with Centella asiatica and Punica granatum extracts. A preliminary study
  publication-title: Journal of the International Academy of Periodontology
– ident: 95
  doi: 10.1080/09637486.2016.1229760
– ident: 127
  doi: 10.3109/09637486.2011.631521
– ident: 155
  doi: 10.1590/s1678-77572006000300003
– ident: 101
  doi: 10.1002/ptr.5643
– volume: 93
  start-page: 3581
  year: 2013
  ident: 134
  article-title: Effects of bioactive‐rich extracts of pomegranate, persimmon, nettle, dill, kale and sideritis and isolated bioactives on arachidonic acid induced markers of platelet activation and aggregation
  publication-title: Journal of the Science of Food and Agriculture
  doi: 10.1002/jsfa.6328
– ident: 26
  doi: 10.3390/molecules22101606
– ident: 138
  doi: 10.1016/j.amjcard.2005.05.026
– ident: 92
  doi: 10.1007/bf03346565
– volume: 13
  start-page: 474
  year: 2011
  ident: 47
  article-title: Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis: a pilot study
  publication-title: The Israel Medical Association Journal
– ident: 79
  doi: 10.1155/2013/932401
– ident: 15
  doi: 10.3390/nu13082577
– ident: 114
  doi: 10.1038/pcan.2015.32
– ident: 27
  doi: 10.2174/1381612825666190708183941
– volume: 42
  start-page: 29
  year: 2011
  ident: 163
  article-title: The antiplaque efficacy of pomegranate mouthrinse
  publication-title: Quintessence international (Berlin, Germany: 1985)
– ident: 63
  doi: 10.1016/j.ctcp.2015.03.001
– volume: 58
  start-page: 1199
  year: 2014
  ident: 107
  article-title: Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients
  publication-title: Molecular Nutrition & Food Research
  doi: 10.1002/mnfr.201300931
– ident: 146
  doi: 10.1159/000330116
– volume: 16
  start-page: 700
  year: 2017
  ident: 58
  article-title: Clinical evaluation of efficacy and safety of appetizer syrup as appetite stimulant in children with non-pathogenic anorexia
  publication-title: Indian Journal of Traditional Knowledge
– ident: 75
  doi: 10.1038/sj.ejcn.1602309
– ident: 144
  doi: 10.1016/j.ctcp.2015.12.003
– volume: 6
  start-page: 1141
  year: 2007
  ident: 67
  article-title: Evaluating the efficacy in improving facial photodamage with a mixture of topical antioxidants
  publication-title: Journal of Drugs in Dermatology: Journal of Drugs in Dermatology
– ident: 158
  doi: 10.1002/ptr.2759
– ident: 90
  doi: 10.1016/j.nutres.2014.08.003
– volume: 7
  start-page: 69
  year: 2020
  ident: 18
  article-title: A comprehensive review about quercus infectoria G. Olivier gall
  publication-title: Research Journal of Pharmacognosy.
– ident: 44
  doi: 10.1007/s40618-019-01139-x
– ident: 24
  doi: 10.1021/np0498051
– ident: 167
  doi: 10.4103/2279-042X.117389
– ident: 94
  doi: 10.3402/fnr.v59.28551
– ident: 96
  doi: 10.1016/j.atherosclerosis.2005.09.006
– ident: 135
  doi: 10.1007/s43440-020-00112-3
– ident: 139
  doi: 10.1002/ptr.5901
– ident: 148
  doi: 10.4103/0972-124x.138678
– ident: 49
  doi: 10.1002/jsfa.7647
– ident: 156
  doi: 10.1016/j.ctcp.2013.08.002
– ident: 91
  doi: 10.1186/2251-6581-11-11
– ident: 154
  doi: 10.1080/j157v06n02_07
– ident: 60
  doi: 10.1016/j.ctim.2016.04.002
– volume: 16
  start-page: 245
  year: 2011
  ident: 132
  article-title: Acute and long term effects of grape and pomegranate juice consumption on endothelial dysfunction in pediatric metabolic syndrome
  publication-title: Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences
– ident: 105
  doi: 10.1016/j.nut.2009.05.003
– ident: 29
  doi: 10.1007/s10600-010-9568-7
– volume: 20
  start-page: 73
  year: 2010
  ident: 131
  article-title: Acute and long term effects of grape and pomegranate juice consumption on vascular reactivity in pediatric metabolic syndrome
  publication-title: Cardiology in the Young
  doi: 10.1017/S1047951109990850
– ident: 17
  doi: 10.1016/j.phytochem.2020.112619
– ident: 16
  doi: 10.3389/fphar.2018.00544
– ident: 108
  doi: 10.1016/j.jnutbio.2017.01.014
– ident: 99
  doi: 10.1016/j.clnesp.2018.11.013
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Snippet Punica granatum L. belongs to the Punicaceae family which is distributed around the world. Different parts of pomegranate like seed, peel, juice, and leaves...
Punica granatum L. belongs to the Punicaceae family which is distributed around the world. Different parts of pomegranate like seed, peel, juice, and leaves...
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SubjectTerms Acids
Arthritis
Bioactive compounds
Cardiovascular diseases
Clinical trials
COVID-19
diabetes
Diabetes mellitus
Drug development
Endocrine disorders
Flavonoids
Fruits
gastrointestinal system
Health aspects
Isoflavones
juices
lignans
Medicinal plants
metabolism
mouth
nutrition
Oral cavity
Polycystic ovary syndrome
Polyphenols
pomegranates
Punica granatum
Review
Reviews
Saponins
Seeds
therapeutics
Traditional medicine
Triterpenes
triterpenoids
Womens health
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Title Therapeutic Effects of Punica granatum (Pomegranate): An Updated Review of Clinical Trials
URI https://dx.doi.org/10.1155/2021/5297162
https://www.proquest.com/docview/2603598088
https://www.proquest.com/docview/2599184516
https://www.proquest.com/docview/2636449181
https://pubmed.ncbi.nlm.nih.gov/PMC8595036
https://doaj.org/article/37017f5b9af247b485f889ed9441542c
Volume 2021
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