Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways - Der, Evan; Suryawanshi, Hemant; Morozov, Pavel; Kustagi, Manjunath; Goilav, Beatrice; Ranabothu, Saritha; Izmirly, Peter; Clancy, Robert; Belmont, H. Michael; Koenigsberg, Mordecai; Mokrzycki, Michele; Rominieki, Helen; et al. (Nature immunology, 2019)
Keywords: 631/250/2520; 631/250/38; 692/420; Autoimmune diseases; Biomedical and Life Sciences; Biomedicine; Biopsy; Care and treatment; Cell Lineage - genetics; Cell proliferation; Computational Biology - methods; Extracellular Matrix Proteins - genetics; Extracellular Matrix Proteins - metabolism; Fibrosis; Gene Expression Profiling - methods; Heterogeneity; Humans; Immunology; Infectious Diseases; Interferon; Interferon Type I - metabolism; Keratinocytes; Keratinocytes - metabolism; Kidney Tubules - cytology; Kidney Tubules - metabolism; Lupus; Lupus nephritis; Lupus Nephritis - genetics; Lupus Nephritis - metabolism; Lupus Nephritis - pathology; Morbidity; Nephritis; Protein Binding; Resource; Ribonucleic acid; RNA; Signal Transduction; Single-Cell Analysis; Skin; Skin - immunology; Skin - metabolism; Skin - pathology; Systemic lupus erythematosus; Transcriptome; California