Freeze-Frame Inhibitor Captures Acetylcholinesterase in a Unique Conformation - Bourne, Yves; Kolb, Hartmuth C.; Radić, Zoran; Sharpless, K. Barry; Taylor, Palmer; Marchot, Pascale (Proceedings of the National Academy of Sciences - PNAS, 2004)
Keywords: Acetylcholinesterase - chemistry; Acetylcholinesterase - drug effects; Atoms; Biochemistry; Biological Sciences; Canyons; Catalysis; Cell Line; Cholinesterase Inhibitors - pharmacology; Crystallization; Cycloaddition; Enzymes; Humans; Indoles; Isomerism; Isomers; Kinetics; Life Sciences; Ligands; Pain; Proteins; Reactants; Temperature; Triazoles