Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas - Knijnenburg, Theo A.; Liu, Yuexin; Kim, Pora; Zhang, Shaojun; Zhao, Zhongming; Laird, Peter W.; Ferguson, Martin L.; Liu, Jia; Lawrence, Michael S.; Saksena, Gordon; Voet, Doug; Dhankani, Varsha; et al. (Cell reports (Cambridge), 2018)
Keywords: Cell Line, Tumor; DNA Damage; DNA damage footprints; DNA damage repair; epigenetic silencing; Gene Silencing; Genome, Human; Humans; integrative statistical analysis; Loss of Heterozygosity; Machine Learning; Mutation; mutational signatures; Neoplasms - classification; Neoplasms - genetics; protein structure analysis; Recombinational DNA Repair; somatic copy-number alterations; somatic mutations; The Cancer Genome Atlas PanCanAtlas project; Tumor Suppressor Proteins - genetics; Tumor Suppressor Proteins - metabolism; somatic mutations; DNA damage repair; protein structure analysis; mutational signatures; somatic copy-number alterations; DNA damage footprints; The Cancer Genome Atlas PanCanAtlas project; epigenetic silencing; integrative statistical analysis