Circulating cell-free mitochondrial DNA, but not leukocyte mitochondrial DNA copy number, is elevated in major depressive disorder - Lindqvist, Daniel; Wolkowitz, Owen M.; Picard, Martin; Ohlsson, Lars; Bersani, Francesco S.; Fernström, Johan; Westrin, Åsa; Hough, Christina M.; Lin, Jue; Reus, Victor I.; Epel, Elissa S.; Mellon, Synthia H. (Neuropsychopharmacology (New York, N.Y.), 2018)
Keywords: Adult; Antidepressants; Antioxidants; Case-Control Studies; Cell-Free Nucleic Acids - blood; Cell-Free Nucleic Acids - drug effects; Clinical Medicine; Copy number; Deoxyribonucleic acid; Depressive Disorder, Major - blood; Depressive Disorder, Major - drug therapy; Depressive Disorder, Major - genetics; DNA; DNA Copy Number Variations - drug effects; DNA Copy Number Variations - genetics; DNA, Mitochondrial - drug effects; DNA, Mitochondrial - genetics; Female; Genomes; Glutathione peroxidase; Glutathione Peroxidase - metabolism; Humans; Klinisk medicin; Leukocytes (mononuclear); Leukocytes, Mononuclear - drug effects; Leukocytes, Mononuclear - metabolism; Male; Medical and Health Sciences; Medicin och hälsovetenskap; Mental depression; Mitochondrial DNA; Mutation; Neurosciences; Peripheral blood mononuclear cells; Pharmacology & Pharmacy; Psychiatry; Psykiatri; Serotonin uptake inhibitors; Serotonin Uptake Inhibitors - pharmacology; Serotonin Uptake Inhibitors - therapeutic use; Smoking; Telomere Homeostasis - genetics; Treatment Outcome; Young Adult