Diagnostic Performance of Magnetic Resonance Elastography in Staging Liver Fibrosis: A Systematic Review and Meta-analysis of Individual Participant Data

• Published in: Clinical gastroenterology and hepatology Vol. 13; no. 3; pp. 440 - 451.e6
• Main Authors: Singh, Siddharth, Venkatesh, Sudhakar K., Wang, Zhen, Miller, Frank H., Motosugi, Utaroh, Low, Russell N., Hassanein, Tarek, Asbach, Patrick, Godfrey, Edmund M., Yin, Meng, Chen, Jun, Keaveny, Andrew P., Bridges, Mellena, Bohte, Anneloes, Murad, Mohammad Hassan, Lomas, David J., Talwalkar, Jayant A., Ehman, Richard L.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2015
• Subjects: Adult; Aged; Biopsy; Diagnostic Performance; Elasticity Imaging Techniques - methods; Elastography; Female; Gastroenterology and Hepatology; Histocytochemistry; Humans; IPD; Liver - diagnostic imaging; Liver - pathology; Liver Cirrhosis - diagnosis; Male; Middle Aged; Noninvasive; Pooled Analysis; ROC Curve; Sensitivity and Specificity; Pooled Analysis; MRE; NAFLD; LR; AUROC; ARFI; TE; Diagnostic Performance; CLD; HCV; IPD; Noninvasive; Elastography; HBV; QUADAS; BMI; hepatitis B virus; transient elastography; Quality Assessment of Diagnostic Accuracy Studies; likelihood ratio; magnetic resonance elastography; hepatitis C virus; chronic liver disease; individual participant data; body mass index; area under the receiver-operating curve; nonalcoholic fatty liver disease; acoustic radiation force impulse imaging

Magnetic resonance elastography (MRE) is a noninvasive tool for staging liver fibrosis. We conducted a meta-analysis of individual participant data collected from published studies to assess the diagnostic accuracy of MRE for staging liver fibrosis in patients with chronic liver diseases (CLD). Thro...