Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses - Kanekiyo, Masaru; Joyce, M. Gordon; Gillespie, Rebecca A.; Gallagher, John R.; Andrews, Sarah F.; Yassine, Hadi M.; Wheatley, Adam K.; Fisher, Brian E.; Ambrozak, David R.; Creanga, Adrian; Leung, Kwanyee; Yang, Eun Sung; et al. (Nature immunology, 2019)
Keywords: 631/250/2152/2153/1291; 631/326/596/1578; 631/61/24/590/2294; Animals; Antibodies; Antibodies, Neutralizing - administration & dosage; Antibodies, Neutralizing - immunology; Antibodies, Viral - immunology; Antigens; Avidity; B cells; B-Lymphocytes - drug effects; B-Lymphocytes - immunology; B-Lymphocytes - virology; Biomedical and Life Sciences; Biomedicine; Composition; Cross Reactions - drug effects; Cross Reactions - immunology; Discordance; Displays (Marketing); Female; Glycoproteins; Health aspects; Hemagglutinin Glycoproteins, Influenza Virus - chemistry; Hemagglutinin Glycoproteins, Influenza Virus - immunology; Hemagglutinins; Humans; Immune response; Immunization; Immunodominance; Immunologic research; Immunology; Infectious Diseases; Influenza; Influenza A; Influenza A Virus, H1N1 Subtype - immunology; Influenza A Virus, H1N1 Subtype - metabolism; Influenza A Virus, H1N1 Subtype - physiology; Influenza vaccines; Influenza Vaccines - administration & dosage; Influenza Vaccines - chemistry; Influenza Vaccines - immunology; Influenza viruses; Influenza, Human - immunology; Influenza, Human - prevention & control; Influenza, Human - virology; Lectins; Lymphocytes B; Mice, Inbred BALB C; Monoclonal antibodies; Nanoparticles; Nanoparticles - chemistry; Orthomyxoviridae Infections - immunology; Orthomyxoviridae Infections - prevention & control; Orthomyxoviridae Infections - virology; Strains (organisms); Swine influenza; Vaccine efficacy; Vaccines; Viruses