Purification of Crimean–Congo hemorrhagic fever virus nucleoprotein and its utility for serological diagnosis

• Published in: Scientific reports Vol. 11; no. 1; pp. 2324 - 11
• Main Authors: Lombe, Boniface Pongombo, Miyamoto, Hiroko, Saito, Takeshi, Yoshida, Reiko, Manzoor, Rashid, Kajihara, Masahiro, Shimojima, Masayuki, Fukushi, Shuetsu, Morikawa, Shigeru, Yoshikawa, Tomoki, Kurosu, Takeshi, Saijo, Masayuki, Tang, Qing, Masumu, Justin, Hawman, David, Feldmann, Heinz, Takada, Ayato
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 27.01.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/326/2521; 631/326/596; Biosafety; Centrifugation; Cesium; Crimean hemorrhagic fever; Enzyme-linked immunosorbent assay; Fever; Hemorrhage; Humanities and Social Sciences; Immunoglobulin G; Lymphocytes T; multidisciplinary; NP gene; Science; Science (multidisciplinary); Seroepidemiology; Zoonoses

Crimean–Congo hemorrhagic fever virus (CCHFV) causes a zoonotic disease, Crimean–Congo hemorrhagic fever (CCHF) endemic in Africa, Asia, the Middle East, and Southeastern Europe. However, the prevalence of CCHF is not monitored in most of the endemic countries due to limited availability of diagnost...