Altered Spontaneous Brain Activity in Type 2 Diabetes: A Resting-State Functional MRI Study

• Published in: Diabetes (New York, N.Y.) Vol. 63; no. 2; pp. 749 - 760
• Main Authors: Cui, Ying, Jiao, Yun, Chen, Yu-Chen, Wang, Kun, Gao, Bo, Wen, Song, Ju, Shenghong, Teng, Gao-Jun
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.02.2014
• Subjects: Aged; Biological and medical sciences; Brain; Brain - physiology; Brain research; Brain waves; Case-Control Studies; Cognition & reasoning; Cognition - physiology; Cognition disorders; Cognitive disorders; Comparative analysis; Diabetes; Diabetes Mellitus, Type 2 - metabolism; Diabetes. Impaired glucose tolerance; Electric properties; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Female; Humans; Magnetic Resonance Imaging; Male; Medical sciences; Middle Aged; NMR; Nuclear magnetic resonance; Observations; Physiological aspects; Type 2 diabetes; Endocrinopathy; Type 2 diabetes; Metabolic diseases; Nuclear magnetic resonance imaging; Central nervous system; Encephalon
• ISSN: 0012-1797; 1939-327X; 1939-327X
• DOI: 10.2337/db13-0519

Previous research has shown that type 2 diabetes mellitus (T2DM) is associated with an increased risk of cognitive impairment. Patients with impaired cognition often show decreased spontaneous brain activity on resting-state functional magnetic resonance imaging (rs-fMRI). This study used rs-fMRI to...