Acute phase dynamics of circulating tumor cells after paclitaxel and doxorubicin chemotherapy in breast cancer mouse models

• Published in: Breast cancer research and treatment Vol. 167; no. 2; pp. 439 - 450
• Main Authors: Adachi, Yayoi, Yoshimura, Mayumi, Nishida, Keiko, Usuki, Hisanobu, Shibata, Keiko, Hattori, Masaya, Kondo, Naoto, Yatabe, Yasushi, Iwata, Hiroji, Kikumori, Toyone, Kodera, Yasuhiro, Nakanishi, Hayao
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.01.2018; Springer; Springer Nature B.V
• Subjects: Animal models; Anthracyclines; Apoptosis; Breast cancer; Cancer metastasis; Cancer research; Cell cycle; Cell growth; Cellular biology; Chemotherapy; Cytology; Doxorubicin; Invasiveness; Medicine; Medicine & Public Health; Metastases; Oncology; Paclitaxel; Preclinical Study; Tumor cells; Preclinical study; Chemotherapy; Breast cancer; CTC; In vivo dynamics; Cytology

Purpose Circulating tumor cells (CTCs) can provide a potentially minimal invasive source for monitoring chemotherapeutic effects. However, detailed in vivo dynamics of CTC after chemotherapy remain largely unknown. Methods We monitored CTC number and morphology early after chemotherapy using a newly...