highly divergent Encephalomyocarditis virus isolated from nonhuman primates in Singapore

BACKGROUND: In 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the Singapore Zoological Gardens. METHODS: Of the four orang utans that underwent post-mortem examination, virus isolation was performed from the ti...

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Published inVirology journal Vol. 10; no. 1; p. 248
Main Authors Yeo, Dawn Su-Yin, Lian, Jing Er, Fernandez, Charlene J, Lin, Yueh-Nuo, Liaw, Jasper Chin-Wen, Soh, Moi-Lien, Lim, Elizabeth Ai-Sim, Chan, Kwai-Peng, Ng, Mah-Lee, Tan, Hwee-Cheng, Oh, Serena, Ooi, Eng-Eong, Tan, Boon-Huan
Format Journal Article
LanguageEnglish
Published England Springer-Verlag 02.08.2013
BioMed Central Ltd
BioMed Central
Subjects
adults
amino acids
Analysis
Animals
Animals, Zoo
Antibodies
antiserum
cell culture
Cercopithecus aethiops
Cluster Analysis
Diagnosis
electron microscopy
Encephalomyocarditis virus
Encephalomyocarditis virus - classification
Encephalomyocarditis virus - genetics
Encephalomyocarditis virus - isolation & purification
etiological agents
gene targeting
genes
Genome, Viral
Genomics
Health aspects
heart
Heart - virology
host range
juveniles
Lung - virology
Microscopy, Electron, Transmission
Molecular Sequence Data
Myocarditis
neutralizing antibodies
Phylogeny
Physiological aspects
Picornaviruses
Pongo - virology
Primates
reverse transcriptase polymerase chain reaction
RNA, Viral - genetics
Sequence Analysis, DNA
Sequence Homology
serological surveys
Singapore
tissue culture
Vero Cells
Viral Proteins - genetics
virion
Virion - ultrastructure
Virus Cultivation
viruses
zoo animals
Zoos
Singapore
Online AccessGet full text

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Abstract BACKGROUND: In 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the Singapore Zoological Gardens. METHODS: Of the four orang utans that underwent post-mortem examination, virus isolation was performed from the tissue homogenates of the heart and lung obtained from the two juvenile orang utans in Vero cell cultures. The tissue culture fluid was examined using electron microscopy. Reverse transcription and polymerase chain reaction with Encephalomyocarditis virus (EMCV)-specific primers targeting the gene regions of VP3/VP1 and 3D polymerase (3Dpol) confirmed the virus genus and species. The two EMCV isolates were sequenced and phylogenetic analyses of the virus genes performed. Serological testing on other animal species in the Singapore Zoological Gardens was also conducted. RESULTS: Electron microscopy of the two EMCV isolates, designated Sing-M100-02 and Sing-M105-02, revealed spherical viral particles of about 20 to 30 nm, consistent with the size and morphology of members belonging to the family Picornaviridae. In addition, infected-Vero cells showed positive immunoflorescence staining with antiserum to EMCV. Sequencing of the viral genome showed that the two EMCV isolates were 99.9% identical at the nucleotide level, indicating a similar source of origin. When compared with existing EMCV sequences in the VP1 and 3Dpol gene regions, the nucleotide divergence were at a maximum of 38.8% and 23.6% respectively, while the amino acid divergence were at a maximum of 33.9% and 11.3% respectively. Phylogenetic analyses of VP1 and 3Dpol genes further grouped the Sing-M100-02 and Sing-M105-02 isolates to themselves, away from existing EMCV lineages. This strongly suggested that Sing-M100-02 and Sing-M105-02 isolates are highly divergent variants of EMCV. Apart from the two deceased orang utans, a serological survey conducted among other zoo animals showed that a number of other animal species had neutralizing antibodies to Sing-M105-02 isolate, indicating that the EMCV variant has a relatively wide host range. CONCLUSIONS: The etiological agent responsible for the fatal myocarditis cases among two of the four orang utans in the Singapore Zoological Gardens was a highly divergent variant of EMCV. This is the first report of an EMCV infection in Singapore and South East Asia.
AbstractList BACKGROUNDIn 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the Singapore Zoological Gardens. METHODSOf the four orang utans that underwent post-mortem examination, virus isolation was performed from the tissue homogenates of the heart and lung obtained from the two juvenile orang utans in Vero cell cultures. The tissue culture fluid was examined using electron microscopy. Reverse transcription and polymerase chain reaction with Encephalomyocarditis virus (EMCV)-specific primers targeting the gene regions of VP3/VP1 and 3D polymerase (3Dpol) confirmed the virus genus and species. The two EMCV isolates were sequenced and phylogenetic analyses of the virus genes performed. Serological testing on other animal species in the Singapore Zoological Gardens was also conducted. RESULTSElectron microscopy of the two EMCV isolates, designated Sing-M100-02 and Sing-M105-02, revealed spherical viral particles of about 20 to 30 nm, consistent with the size and morphology of members belonging to the family Picornaviridae. In addition, infected-Vero cells showed positive immunoflorescence staining with antiserum to EMCV. Sequencing of the viral genome showed that the two EMCV isolates were 99.9% identical at the nucleotide level, indicating a similar source of origin. When compared with existing EMCV sequences in the VP1 and 3Dpol gene regions, the nucleotide divergence were at a maximum of 38.8% and 23.6% respectively, while the amino acid divergence were at a maximum of 33.9% and 11.3% respectively. Phylogenetic analyses of VP1 and 3Dpol genes further grouped the Sing-M100-02 and Sing-M105-02 isolates to themselves, away from existing EMCV lineages. This strongly suggested that Sing-M100-02 and Sing-M105-02 isolates are highly divergent variants of EMCV. Apart from the two deceased orang utans, a serological survey conducted among other zoo animals showed that a number of other animal species had neutralizing antibodies to Sing-M105-02 isolate, indicating that the EMCV variant has a relatively wide host range. CONCLUSIONSThe etiological agent responsible for the fatal myocarditis cases among two of the four orang utans in the Singapore Zoological Gardens was a highly divergent variant of EMCV. This is the first report of an EMCV infection in Singapore and South East Asia.
In 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the Singapore Zoological Gardens. Of the four orang utans that underwent post-mortem examination, virus isolation was performed from the tissue homogenates of the heart and lung obtained from the two juvenile orang utans in Vero cell cultures. The tissue culture fluid was examined using electron microscopy. Reverse transcription and polymerase chain reaction with Encephalomyocarditis virus (EMCV)-specific primers targeting the gene regions of VP3/VP1 and 3D polymerase (3Dpol) confirmed the virus genus and species. The two EMCV isolates were sequenced and phylogenetic analyses of the virus genes performed. Serological testing on other animal species in the Singapore Zoological Gardens was also conducted. Electron microscopy of the two EMCV isolates, designated Sing-M100-02 and Sing-M105-02, revealed spherical viral particles of about 20 to 30 nm, consistent with the size and morphology of members belonging to the family Picornaviridae. In addition, infected-Vero cells showed positive immunoflorescence staining with antiserum to EMCV. Sequencing of the viral genome showed that the two EMCV isolates were 99.9% identical at the nucleotide level, indicating a similar source of origin. When compared with existing EMCV sequences in the VP1 and 3Dpol gene regions, the nucleotide divergence were at a maximum of 38.8% and 23.6% respectively, while the amino acid divergence were at a maximum of 33.9% and 11.3% respectively. Phylogenetic analyses of VP1 and 3Dpol genes further grouped the Sing-M100-02 and Sing-M105-02 isolates to themselves, away from existing EMCV lineages. This strongly suggested that Sing-M100-02 and Sing-M105-02 isolates are highly divergent variants of EMCV. Apart from the two deceased orang utans, a serological survey conducted among other zoo animals showed that a number of other animal species had neutralizing antibodies to Sing-M105-02 isolate, indicating that the EMCV variant has a relatively wide host range. The etiological agent responsible for the fatal myocarditis cases among two of the four orang utans in the Singapore Zoological Gardens was a highly divergent variant of EMCV. This is the first report of an EMCV infection in Singapore and South East Asia.
In 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the Singapore Zoological Gardens. Of the four orang utans that underwent post-mortem examination, virus isolation was performed from the tissue homogenates of the heart and lung obtained from the two juvenile orang utans in Vero cell cultures. The tissue culture fluid was examined using electron microscopy. Reverse transcription and polymerase chain reaction with Encephalomyocarditis virus (EMCV)-specific primers targeting the gene regions of VP3/VP1 and 3D polymerase (3Dpol) confirmed the virus genus and species. The two EMCV isolates were sequenced and phylogenetic analyses of the virus genes performed. Serological testing on other animal species in the Singapore Zoological Gardens was also conducted. Electron microscopy of the two EMCV isolates, designated Sing-M100-02 and Sing-M105-02, revealed spherical viral particles of about 20 to 30 nm, consistent with the size and morphology of members belonging to the family Picornaviridae. In addition, infected-Vero cells showed positive immunoflorescence staining with antiserum to EMCV. Sequencing of the viral genome showed that the two EMCV isolates were 99.9% identical at the nucleotide level, indicating a similar source of origin. When compared with existing EMCV sequences in the VP1 and 3Dpol gene regions, the nucleotide divergence were at a maximum of 38.8% and 23.6% respectively, while the amino acid divergence were at a maximum of 33.9% and 11.3% respectively. Phylogenetic analyses of VP1 and 3Dpol genes further grouped the Sing-M100-02 and Sing-M105-02 isolates to themselves, away from existing EMCV lineages. This strongly suggested that Sing-M100-02 and Sing-M105-02 isolates are highly divergent variants of EMCV. Apart from the two deceased orang utans, a serological survey conducted among other zoo animals showed that a number of other animal species had neutralizing antibodies to Sing-M105-02 isolate, indicating that the EMCV variant has a relatively wide host range. The etiological agent responsible for the fatal myocarditis cases among two of the four orang utans in the Singapore Zoological Gardens was a highly divergent variant of EMCV. This is the first report of an EMCV infection in Singapore and South East Asia.
BACKGROUND: In 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the Singapore Zoological Gardens. METHODS: Of the four orang utans that underwent post-mortem examination, virus isolation was performed from the tissue homogenates of the heart and lung obtained from the two juvenile orang utans in Vero cell cultures. The tissue culture fluid was examined using electron microscopy. Reverse transcription and polymerase chain reaction with Encephalomyocarditis virus (EMCV)-specific primers targeting the gene regions of VP3/VP1 and 3D polymerase (3Dpol) confirmed the virus genus and species. The two EMCV isolates were sequenced and phylogenetic analyses of the virus genes performed. Serological testing on other animal species in the Singapore Zoological Gardens was also conducted. RESULTS: Electron microscopy of the two EMCV isolates, designated Sing-M100-02 and Sing-M105-02, revealed spherical viral particles of about 20 to 30 nm, consistent with the size and morphology of members belonging to the family Picornaviridae. In addition, infected-Vero cells showed positive immunoflorescence staining with antiserum to EMCV. Sequencing of the viral genome showed that the two EMCV isolates were 99.9% identical at the nucleotide level, indicating a similar source of origin. When compared with existing EMCV sequences in the VP1 and 3Dpol gene regions, the nucleotide divergence were at a maximum of 38.8% and 23.6% respectively, while the amino acid divergence were at a maximum of 33.9% and 11.3% respectively. Phylogenetic analyses of VP1 and 3Dpol genes further grouped the Sing-M100-02 and Sing-M105-02 isolates to themselves, away from existing EMCV lineages. This strongly suggested that Sing-M100-02 and Sing-M105-02 isolates are highly divergent variants of EMCV. Apart from the two deceased orang utans, a serological survey conducted among other zoo animals showed that a number of other animal species had neutralizing antibodies to Sing-M105-02 isolate, indicating that the EMCV variant has a relatively wide host range. CONCLUSIONS: The etiological agent responsible for the fatal myocarditis cases among two of the four orang utans in the Singapore Zoological Gardens was a highly divergent variant of EMCV. This is the first report of an EMCV infection in Singapore and South East Asia.
Background: In 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the Singapore Zoological Gardens. Methods: Of the four orang utans that underwent post-mortem examination, virus isolation was performed from the tissue homogenates of the heart and lung obtained from the two juvenile orang utans in Vero cell cultures. The tissue culture fluid was examined using electron microscopy. Reverse transcription and polymerase chain reaction with Encephalomyocarditis virus (EMCV)-specific primers targeting the gene regions of VP3/VP1 and 3D polymerase (3Dpol) confirmed the virus genus and species. The two EMCV isolates were sequenced and phylogenetic analyses of the virus genes performed. Serological testing on other animal species in the Singapore Zoological Gardens was also conducted. Results: Electron microscopy of the two EMCV isolates, designated Sing-M100-02 and Sing-M105-02, revealed spherical viral particles of about 20 to 30 nm, consistent with the size and morphology of members belonging to the family Picornaviridae. In addition, infected-Vero cells showed positive immunoflorescence staining with antiserum to EMCV. Sequencing of the viral genome showed that the two EMCV isolates were 99.9% identical at the nucleotide level, indicating a similar source of origin. When compared with existing EMCV sequences in the VP1 and 3Dpol gene regions, the nucleotide divergence were at a maximum of 38.8% and 23.6% respectively, while the amino acid divergence were at a maximum of 33.9% and 11.3% respectively. Phylogenetic analyses of VP1 and 3Dpol genes further grouped the Sing-M100-02 and Sing-M105-02 isolates to themselves, away from existing EMCV lineages. This strongly suggested that Sing-M100-02 and Sing-M105-02 isolates are highly divergent variants of EMCV. Apart from the two deceased orang utans, a serological survey conducted among other zoo animals showed that a number of other animal species had neutralizing antibodies to Sing-M105-02 isolate, indicating that the EMCV variant has a relatively wide host range. Conclusions: The etiological agent responsible for the fatal myocarditis cases among two of the four orang utans in the Singapore Zoological Gardens was a highly divergent variant of EMCV. This is the first report of an EMCV infection in Singapore and South East Asia.
Background In 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the Singapore Zoological Gardens. Methods Of the four orang utans that underwent post-mortem examination, virus isolation was performed from the tissue homogenates of the heart and lung obtained from the two juvenile orang utans in Vero cell cultures. The tissue culture fluid was examined using electron microscopy. Reverse transcription and polymerase chain reaction with Encephalomyocarditis virus (EMCV)-specific primers targeting the gene regions of VP3/VP1 and 3D polymerase (3Dpol) confirmed the virus genus and species. The two EMCV isolates were sequenced and phylogenetic analyses of the virus genes performed. Serological testing on other animal species in the Singapore Zoological Gardens was also conducted. Results Electron microscopy of the two EMCV isolates, designated Sing-M100-02 and Sing-M105-02, revealed spherical viral particles of about 20 to 30 nm, consistent with the size and morphology of members belonging to the family Picornaviridae. In addition, infected-Vero cells showed positive immunoflorescence staining with antiserum to EMCV. Sequencing of the viral genome showed that the two EMCV isolates were 99.9% identical at the nucleotide level, indicating a similar source of origin. When compared with existing EMCV sequences in the VP1 and 3Dpol gene regions, the nucleotide divergence were at a maximum of 38.8% and 23.6% respectively, while the amino acid divergence were at a maximum of 33.9% and 11.3% respectively. Phylogenetic analyses of VP1 and 3Dpol genes further grouped the Sing-M100-02 and Sing-M105-02 isolates to themselves, away from existing EMCV lineages. This strongly suggested that Sing-M100-02 and Sing-M105-02 isolates are highly divergent variants of EMCV. Apart from the two deceased orang utans, a serological survey conducted among other zoo animals showed that a number of other animal species had neutralizing antibodies to Sing-M105-02 isolate, indicating that the EMCV variant has a relatively wide host range. Conclusions The etiological agent responsible for the fatal myocarditis cases among two of the four orang utans in the Singapore Zoological Gardens was a highly divergent variant of EMCV. This is the first report of an EMCV infection in Singapore and South East Asia. Keywords: Encephalomyocarditis virus, Variant virus, Fatal acute myocarditis, Orang utan
ArticleNumber 248
Audience Academic
Author Lin, Yueh-Nuo
Ooi, Eng-Eong
Lim, Elizabeth Ai-Sim
Tan, Boon-Huan
Fernandez, Charlene J
Lian, Jing Er
Liaw, Jasper Chin-Wen
Tan, Hwee-Cheng
Yeo, Dawn Su-Yin
Soh, Moi-Lien
Oh, Serena
Chan, Kwai-Peng
Ng, Mah-Lee
AuthorAffiliation 7 Wildlife Reserves Singapore, Singapore, Singapore
9 Department of Civil and Environmental Engineering, National University of Singapore, Singapore, Singapore
1 Defence Medical and Environmental Research Institute, DSO National Laboratories, #13-00, 27 Medical Drive, Buona 117510, Singapore
3 Agri-Food and Veterinary Authority of Singapore, Singapore, Singapore
2 School of Biological Sciences, Nanyang Technological University, Nanyang, Singapore
6 Duke-NUS GMS, National University of Singapore, Singapore, Singapore
4 Department of Pathology, Singapore General Hospital, Changi, Singapore
5 Department of Microbiology, National University of Singapore, Singapore, Singapore
8 Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore
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Cites_doi 10.1016/S0140-6736(48)90652-7
10.1128/JVI.73.3.1941-1948.1999
10.1007/BF00164022
10.1016/j.vetmic.2012.08.008
10.1146/annurev.micro.51.1.151
10.1128/JCM.36.12.3463-3467.1998
10.1371/journal.ppat.1001005
10.1006/viro.2000.0320
10.1016/j.vetmic.2005.10.032
10.1126/science.3026048
10.1099/0022-1317-72-9-2197
10.1128/JVI.75.16.7732-7738.2001
10.1111/j.1600-0684.2010.00464.x
10.1016/j.vetmic.2012.07.006
10.1354/vp.36-5-452
10.1099/0022-1317-81-3-803
10.1016/0042-6822(91)90464-M
10.1177/0300985811409254
10.1007/s10517-005-0293-3
10.1128/JCM.38.3.1170-1174.2000
10.1017/S0950268804003668
10.1128/JVI.73.12.9969-9975.1999
10.1099/0022-1317-81-5-1361
10.3201/eid1504.081428
10.1093/genetics/157.1.7
10.2307/20094890
10.1016/S0034-5288(97)90197-1
10.1016/S0166-0934(97)02214-3
10.1542/peds.16.6.902
10.1186/1743-422X-7-64
10.1002/1096-9071(200101)63:1<35::AID-JMV1005>3.0.CO;2-Q
10.1093/nar/12.6.2969
10.1016/0022-2836(88)90367-1
10.1099/0022-1317-82-2-409
10.1128/JVI.76.18.9516-9525.2002
10.1007/s007050050554
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References 9971773 - J Virol. 1999 Mar;73(3):1941-8
10699015 - J Clin Microbiol. 2000 Mar;38(3):1170-4
11462047 - J Virol. 2001 Aug;75(16):7732-8
3225850 - J Mol Biol. 1988 Dec 5;204(3):771-6
15962562 - Epidemiol Infect. 2005 Jun;133(3):547-57
21653204 - Vet Pathol. 2012 Mar;49(2):386-92
10792982 - Virology. 2000 May 10;270(2):251-3
9279403 - J Zoo Wildl Med. 1997 Jun;28(2):153-7
10490214 - Vet Pathol. 1999 Sep;36(5):452-6
200596 - J Am Vet Med Assoc. 1977 Nov 1;171(9):902-5
23021643 - Vet Microbiol. 2013 Feb 22;162(1):23-31
1895057 - J Gen Virol. 1991 Sep;72 ( Pt 9):2197-206
11130885 - J Med Virol. 2001 Jan;63(1):35-44
11161280 - J Gen Virol. 2001 Feb;82(Pt 2):409-16
1320151 - Lab Anim Sci. 1992 Jun;42(3):233-9
8902363 - Comput Appl Biosci. 1996 Aug;12(4):357-8
18877580 - Lancet. 1948 Aug 21;2(6521):286-9
9343347 - Annu Rev Microbiol. 1997;51:151-78
7769613 - J Mol Evol. 1995 Apr;40(4):362-71
9300541 - Res Vet Sci. 1997 May-Jun;62(3):239-44
2159671 - Vet Rec. 1990 Apr 14;126(15):364-5
16406410 - Vet Microbiol. 2006 Mar 10;113(1-2):1-12
10769080 - J Gen Virol. 2000 May;81(Pt 5):1361-72
19331761 - Emerg Infect Dis. 2009 Apr;15(4):640-6
20298561 - Virol J. 2010;7:64
10675418 - J Gen Virol. 2000 Mar;81(Pt 3):803-12
9220393 - J Virol Methods. 1997 Jun;66(1):83-9
16027852 - Bull Exp Biol Med. 2005 Mar;139(3):355-9
12186933 - J Virol. 2002 Sep;76(18):9516-25
9817855 - J Clin Microbiol. 1998 Dec;36(12):3463-7
8600443 - Onderstepoort J Vet Res. 1995 Jun;62(2):97-108
13273129 - Pediatrics. 1955 Dec;16(6):902-6
21323673 - J Med Primatol. 2011 Jun;40(3):157-63
3026048 - Science. 1987 Jan 9;235(4785):182-91
10416373 - Arch Virol. 1999;144(5):893-903
20661479 - PLoS Pathog. 2010;6(7):e1001005
6324136 - Nucleic Acids Res. 1984 Mar 26;12(6):2969-85
11139487 - Genetics. 2001 Jan;157(1):7-15
10559310 - J Virol. 1999 Dec;73(12):9969-75
1704653 - Virology. 1991 Mar;181(1):1-13
22824255 - Vet Microbiol. 2012 Dec 28;161(1-2):49-57
F Koenen (2240_CR13) 1997; 62
RI Krylova (2240_CR11) 2005; 139
E Paschaleri-Papadopoulou (2240_CR14) 1990; 124
E Domingo (2240_CR47) 1997; 51
M Costa-Mattioli (2240_CR42) 2002; 76
EW Koonin (2240_CR43) 1991; 72
DC Gajdusek (2240_CR20) 1955; 16
MS Oberste (2240_CR22) 2009; 15
A Villaverde (2240_CR46) 1988; 204
JJ Zimmerman (2240_CR33) 1994
MS Oberste (2240_CR24) 2000; 38
AS Lauring (2240_CR49) 2010; 6
H Vanderhallen (2240_CR27) 1997; 66
LA Reddacliff (2240_CR3) 1997; 28
SB Citino (2240_CR6) 1998; 19
A Philipps (2240_CR29) 2012; 161
H Norder (2240_CR38) 2001; 63
SK Wells (2240_CR7) 1989; 20
P Denis (2240_CR32) 2006; 113
MN Mulders (2240_CR37) 2000; 81
H Vanderhallen (2240_CR28) 1998; 36
MS Oberste (2240_CR40) 2001; 82
DG Grobler (2240_CR9) 1995; 62
MS Oberste (2240_CR39) 1999; 73
NJ Knowles (2240_CR23) 2012
H Maurice (2240_CR16) 2005; 133
DG Hu (2240_CR18) 1993
NY Park (2240_CR17) 1992; 32
K Masek-Hammerman (2240_CR5) 2012; 49
HS Joo (2240_CR12) 1992
M Luo (2240_CR30) 1987; 235
P McMinn (2240_CR36) 2001; 75
BA Brown (2240_CR34) 1999; 73
L Sidoli (2240_CR15) 1989; 30
AC Palmberg (2240_CR45) 1984; 12
Page RDM (2240_CR50) 1996; 12
GWA Dick (2240_CR21) 1948; 252
U Boege (2240_CR31) 1991; 181
JH van Sandwyk (2240_CR10) 2013; 162
CF Simpson (2240_CR8) 1977; 171
F Koenen (2240_CR26) 1999; 144
GB Hubbard (2240_CR2) 1992; 42
J Santti (2240_CR41) 2000; 81
J Miyagi (2240_CR19) 1999; 36
E Canelli (2240_CR4) 2010; 7
MJ Rodrigo (2240_CR44) 1995; 40
E Domingo (2240_CR48) 2000; 270
P Jones (2240_CR1) 2011; 40
AR Rotbart (2240_CR25) 1990
DT Haydon (2240_CR35) 2001; 157
References_xml – volume: 42
  start-page: 233
  year: 1992
  ident: 2240_CR2
  publication-title: Lab Anim Sci
  contributor:
    fullname: GB Hubbard
– volume: 28
  start-page: 153
  year: 1997
  ident: 2240_CR3
  publication-title: J Zool Wild Med
  contributor:
    fullname: LA Reddacliff
– volume: 252
  start-page: 286
  year: 1948
  ident: 2240_CR21
  publication-title: Lancet
  doi: 10.1016/S0140-6736(48)90652-7
  contributor:
    fullname: GWA Dick
– volume: 73
  start-page: 1941
  year: 1999
  ident: 2240_CR39
  publication-title: J Virol
  doi: 10.1128/JVI.73.3.1941-1948.1999
  contributor:
    fullname: MS Oberste
– volume: 40
  start-page: 362
  year: 1995
  ident: 2240_CR44
  publication-title: J Mol Evol
  doi: 10.1007/BF00164022
  contributor:
    fullname: MJ Rodrigo
– volume: 124
  start-page: 364
  year: 1990
  ident: 2240_CR14
  publication-title: Vet Rec
  contributor:
    fullname: E Paschaleri-Papadopoulou
– volume: 162
  start-page: 23
  year: 2013
  ident: 2240_CR10
  publication-title: Vet Microbiol
  doi: 10.1016/j.vetmic.2012.08.008
  contributor:
    fullname: JH van Sandwyk
– volume: 51
  start-page: 151
  year: 1997
  ident: 2240_CR47
  publication-title: Ann Rev Microbiol
  doi: 10.1146/annurev.micro.51.1.151
  contributor:
    fullname: E Domingo
– volume: 36
  start-page: 3463
  year: 1998
  ident: 2240_CR28
  publication-title: J Clin Microbiol
  doi: 10.1128/JCM.36.12.3463-3467.1998
  contributor:
    fullname: H Vanderhallen
– volume: 6
  start-page: e1001005
  year: 2010
  ident: 2240_CR49
  publication-title: PLoS Pathog
  doi: 10.1371/journal.ppat.1001005
  contributor:
    fullname: AS Lauring
– volume: 32
  start-page: 99
  year: 1992
  ident: 2240_CR17
  publication-title: Korea J Vet Res
  contributor:
    fullname: NY Park
– volume: 20
  start-page: 291
  year: 1989
  ident: 2240_CR7
  publication-title: J Zool Wild Med
  contributor:
    fullname: SK Wells
– volume: 270
  start-page: 251
  year: 2000
  ident: 2240_CR48
  publication-title: Virology
  doi: 10.1006/viro.2000.0320
  contributor:
    fullname: E Domingo
– volume: 113
  start-page: 1
  year: 2006
  ident: 2240_CR32
  publication-title: Vet Microbiol
  doi: 10.1016/j.vetmic.2005.10.032
  contributor:
    fullname: P Denis
– volume: 235
  start-page: 182
  year: 1987
  ident: 2240_CR30
  publication-title: Science
  doi: 10.1126/science.3026048
  contributor:
    fullname: M Luo
– start-page: 423
  volume-title: CRC handbook series in zoonoses. Section B: viral zoonoses
  year: 1994
  ident: 2240_CR33
  contributor:
    fullname: JJ Zimmerman
– volume: 62
  start-page: 97
  year: 1995
  ident: 2240_CR9
  publication-title: Onderstepoort J Vet Res
  contributor:
    fullname: DG Grobler
– volume: 72
  start-page: 2197
  year: 1991
  ident: 2240_CR43
  publication-title: J Gen Virol
  doi: 10.1099/0022-1317-72-9-2197
  contributor:
    fullname: EW Koonin
– start-page: 372
  volume-title: PCR protocols: a guide to methods and amplifications
  year: 1990
  ident: 2240_CR25
  contributor:
    fullname: AR Rotbart
– volume: 75
  start-page: 7732
  year: 2001
  ident: 2240_CR36
  publication-title: J Virol
  doi: 10.1128/JVI.75.16.7732-7738.2001
  contributor:
    fullname: P McMinn
– volume: 40
  start-page: 157
  year: 2011
  ident: 2240_CR1
  publication-title: J Med Primatol
  doi: 10.1111/j.1600-0684.2010.00464.x
  contributor:
    fullname: P Jones
– start-page: 149
  volume-title: Epidemiological studies of swine Encephalomyocarditis virus infection
  year: 1993
  ident: 2240_CR18
  contributor:
    fullname: DG Hu
– volume: 161
  start-page: 49
  year: 2012
  ident: 2240_CR29
  publication-title: Vet Microbiol
  doi: 10.1016/j.vetmic.2012.07.006
  contributor:
    fullname: A Philipps
– volume: 36
  start-page: 452
  year: 1999
  ident: 2240_CR19
  publication-title: Vet Path
  doi: 10.1354/vp.36-5-452
  contributor:
    fullname: J Miyagi
– volume: 81
  start-page: 803
  year: 2000
  ident: 2240_CR37
  publication-title: J Gen Virol
  doi: 10.1099/0022-1317-81-3-803
  contributor:
    fullname: MN Mulders
– volume: 181
  start-page: 1
  year: 1991
  ident: 2240_CR31
  publication-title: Virology
  doi: 10.1016/0042-6822(91)90464-M
  contributor:
    fullname: U Boege
– volume: 49
  start-page: 386
  year: 2012
  ident: 2240_CR5
  publication-title: Vet Path
  doi: 10.1177/0300985811409254
  contributor:
    fullname: K Masek-Hammerman
– volume: 30
  start-page: 249
  year: 1989
  ident: 2240_CR15
  publication-title: Selozoine Vet
  contributor:
    fullname: L Sidoli
– volume: 171
  start-page: 902
  year: 1977
  ident: 2240_CR8
  publication-title: J Am Vet Med Assoc
  contributor:
    fullname: CF Simpson
– volume: 139
  start-page: 355
  year: 2005
  ident: 2240_CR11
  publication-title: Bull Exp Biol Med
  doi: 10.1007/s10517-005-0293-3
  contributor:
    fullname: RI Krylova
– volume: 38
  start-page: 1170
  year: 2000
  ident: 2240_CR24
  publication-title: J Clin Microbiol
  doi: 10.1128/JCM.38.3.1170-1174.2000
  contributor:
    fullname: MS Oberste
– volume: 133
  start-page: 547
  year: 2005
  ident: 2240_CR16
  publication-title: Epidemiol Infect
  doi: 10.1017/S0950268804003668
  contributor:
    fullname: H Maurice
– volume: 73
  start-page: 9969
  year: 1999
  ident: 2240_CR34
  publication-title: J Virol
  doi: 10.1128/JVI.73.12.9969-9975.1999
  contributor:
    fullname: BA Brown
– volume: 81
  start-page: 1361
  year: 2000
  ident: 2240_CR41
  publication-title: J Gen Virol
  doi: 10.1099/0022-1317-81-5-1361
  contributor:
    fullname: J Santti
– volume: 15
  start-page: 640
  year: 2009
  ident: 2240_CR22
  publication-title: Emerg Infect Dis
  doi: 10.3201/eid1504.081428
  contributor:
    fullname: MS Oberste
– volume: 157
  start-page: 7
  year: 2001
  ident: 2240_CR35
  publication-title: Genetics
  doi: 10.1093/genetics/157.1.7
  contributor:
    fullname: DT Haydon
– volume: 19
  start-page: 214
  year: 1998
  ident: 2240_CR6
  publication-title: J Zoo Wildl Med
  doi: 10.2307/20094890
  contributor:
    fullname: SB Citino
– volume: 62
  start-page: 239
  year: 1997
  ident: 2240_CR13
  publication-title: Res Vet Sci
  doi: 10.1016/S0034-5288(97)90197-1
  contributor:
    fullname: F Koenen
– volume: 66
  start-page: 83
  year: 1997
  ident: 2240_CR27
  publication-title: J Virol Met
  doi: 10.1016/S0166-0934(97)02214-3
  contributor:
    fullname: H Vanderhallen
– start-page: 855
  volume-title: Virus taxonomy: classification and nomenclature of viruses: ninth report of the international committee on taxonomy of viruses
  year: 2012
  ident: 2240_CR23
  contributor:
    fullname: NJ Knowles
– volume: 16
  start-page: 902
  year: 1955
  ident: 2240_CR20
  publication-title: Pedriatrics
  doi: 10.1542/peds.16.6.902
  contributor:
    fullname: DC Gajdusek
– volume: 12
  start-page: 357
  year: 1996
  ident: 2240_CR50
  publication-title: Comp Appl Biosci
  contributor:
    fullname: Page RDM
– volume: 7
  start-page: 64
  year: 2010
  ident: 2240_CR4
  publication-title: Virol J
  doi: 10.1186/1743-422X-7-64
  contributor:
    fullname: E Canelli
– volume: 63
  start-page: 35
  year: 2001
  ident: 2240_CR38
  publication-title: J Med Virol
  doi: 10.1002/1096-9071(200101)63:1<35::AID-JMV1005>3.0.CO;2-Q
  contributor:
    fullname: H Norder
– volume: 12
  start-page: 2969
  year: 1984
  ident: 2240_CR45
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/12.6.2969
  contributor:
    fullname: AC Palmberg
– volume: 204
  start-page: 771
  year: 1988
  ident: 2240_CR46
  publication-title: J Mol Biol
  doi: 10.1016/0022-2836(88)90367-1
  contributor:
    fullname: A Villaverde
– volume: 82
  start-page: 409
  year: 2001
  ident: 2240_CR40
  publication-title: J Gen Virol
  doi: 10.1099/0022-1317-82-2-409
  contributor:
    fullname: MS Oberste
– start-page: 257
  volume-title: Diseases of Swine
  year: 1992
  ident: 2240_CR12
  contributor:
    fullname: HS Joo
– volume: 76
  start-page: 9516
  year: 2002
  ident: 2240_CR42
  publication-title: J Virol
  doi: 10.1128/JVI.76.18.9516-9525.2002
  contributor:
    fullname: M Costa-Mattioli
– volume: 144
  start-page: 893
  year: 1999
  ident: 2240_CR26
  publication-title: Arch Virol
  doi: 10.1007/s007050050554
  contributor:
    fullname: F Koenen
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Snippet BACKGROUND: In 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the...
In 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the Singapore...
Background In 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the...
Background: In 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the...
BACKGROUNDIn 2001 and 2002, fatal myocarditis resulted in the sudden deaths of four, two adult and two juvenile, orang utans out of a cohort of 26 in the...
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SubjectTerms adults
amino acids
Analysis
Animals
Animals, Zoo
Antibodies
antiserum
cell culture
Cercopithecus aethiops
Cluster Analysis
Diagnosis
electron microscopy
Encephalomyocarditis virus
Encephalomyocarditis virus - classification
Encephalomyocarditis virus - genetics
Encephalomyocarditis virus - isolation & purification
etiological agents
gene targeting
genes
Genome, Viral
Genomics
Health aspects
heart
Heart - virology
host range
juveniles
Lung - virology
Microscopy, Electron, Transmission
Molecular Sequence Data
Myocarditis
neutralizing antibodies
Phylogeny
Physiological aspects
Picornaviruses
Pongo - virology
Primates
reverse transcriptase polymerase chain reaction
RNA, Viral - genetics
Sequence Analysis, DNA
Sequence Homology
serological surveys
Singapore
tissue culture
Vero Cells
Viral Proteins - genetics
virion
Virion - ultrastructure
Virus Cultivation
viruses
zoo animals
Zoos
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Title highly divergent Encephalomyocarditis virus isolated from nonhuman primates in Singapore
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