The annual impact of seasonal influenza in the US: Measuring disease burden and costs

• Published in: Vaccine Vol. 25; no. 27; pp. 5086 - 5096
• Main Authors: Molinari, Noelle-Angelique M, Ortega-Sanchez, Ismael R, Messonnier, Mark L, Thompson, William W, Wortley, Pascale M, Weintraub, Eric, Bridges, Carolyn B
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 28.06.2007; Elsevier; Elsevier Limited
• Subjects: Adolescent; Adult; Age; Aged; Algorithms; Allergy and Immunology; Applied microbiology; Biological and medical sciences; Child; Child, Preschool; Confidence intervals; Cost of Illness; Costs; Costs and Cost Analysis; Disease burden; Economics; Efficiency; Epidemics; Estimates; Female; Fundamental and applied biological sciences. Psychology; Health care expenditures; Health-care cost; Hospitalization; Hospitalization - economics; Humans; Illnesses; Immunization; Infant; Infections; Influenza; Influenza, Human - economics; Influenza, Human - epidemiology; Influenza, Human - mortality; Male; Microbiology; Middle Aged; Monte Carlo Method; Morbidity; Mortality; Pandemics; Pneumonia; Population; Probability; Productivity losses; Regression Analysis; Risk; Sick Leave - economics; Studies; Treatment Outcome; United States - epidemiology; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); Value of Life; United States; United States > US; Productivity losses; Health-care cost; Disease burden; Influenza; Infection; Viral disease

Abstract Background Despite preventive efforts, influenza epidemics are responsible for substantial morbidity and mortality every year in the United States (US). Vaccination strategies to reduce disease burden have been implemented. However, no previous studies have systematically estimated the annu...