Effectiveness of age-based strategies to increase influenza vaccination coverage among high risk subjects in Madrid (Spain)

• Published in: Vaccine Vol. 29; no. 16; pp. 2840 - 2845
• Main Authors: Jiménez-García, Rodrigo, Rodríguez-Rieiro, Cristina, Hernández-Barrera, Valentín, Andres, Ana Lopez de, Cuadrado, Agustin Rivero, Laso, Angel Rodriguez, Carrasco-Garrido, Pilar
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 05.04.2011; Elsevier; Elsevier Limited
• Subjects: Adherence; Adolescent; Adult; Age; Age Distribution; Aged; Allergy and Immunology; Applied microbiology; Asthma; Biological and medical sciences; Bronchitis; Cardiovascular disease; Chronic illnesses; Coverage; Diabetes; Embolisms; Female; Fundamental and applied biological sciences. Psychology; Heart attacks; Humans; Immunization; Influenza; Influenza Vaccines - administration & dosage; Influenza, Human - epidemiology; Influenza, Human - prevention & control; Logistic Models; Male; Microbiology; Middle Aged; Mortality; Multivariate Analysis; risk; Spain; Spain - epidemiology; Strategies; surveys; vaccination; Vaccination - statistics & numerical data; Vaccine; Vaccines; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); Variables; Young Adult; Spain; Southern Europe; Europe; Adherence; Vaccine; Coverage; Influenza; Strategies; Infection; Vaccination coverage; Viral disease; Adhesion; Age
• ISSN: 0264-410X; 1873-2518; 1873-2518
• DOI: 10.1016/j.vaccine.2011.02.004

► The probability of a subject aged 60–64 living in Madrid of being vaccinated was almost two times higher (OR 1.95 CI 95% 1.46–2.61) than a person of the same age who lived in a region of Spain where the universal recommendation for influenza vaccine started at 65 years. ► Lowering the age for universal influenza vaccination should be considered as a strategy to increase coverages among high risk patients who suffer from chronic underlying conditions. We aim to assess the effectiveness of age-based strategies to increase influenza vaccination coverage among high risk subjects. To do so, we describe and compare the influenza vaccination coverage in the 2006/2007 campaign between the Autonomous Community of Madrid (ACM), where in year 2005 the recommendation was extended by 5 years to cover all those aged 60 and over, and other regions of Spain where the universally recommended age was 65 years and above. We used individualized secondary data provided by two surveys carried out in 2007 in ACM and in the rest of Spain. The total number of subjects included in the study was 21,948. For the 60–64 years age group influenza vaccination coverage was significantly higher 40.1% (CI 95% 36.4–43.8) in ACM residents than among residents in the Rest of Spain 29.1% (CI 95% 24.5–33.7). The difference in vaccine uptake was even greater, 59% (CI 95% 51.8–66.2) vs. 43.5%(CI 95% 34.3–52.7), when we compared subjects who suffered a chronic condition, which represents an indication for the anti-influenza vaccination. The results of the multivariate analysis show that the probability of a subject aged 60–64 living in ACM of being vaccinated was almost two times higher (OR 1.95 CI 95% 1.46–2.61) than a person of the same age who lived in a region of Spain where the universal recommendation for influenza vaccine started at 65 years. In conclusion, the available evidence indicates the effectiveness of age-based strategies to increase influenza vaccination coverage among high risk subjects aged 60–64 years in our population.