Profound CD8+ T cell immunity elicited by sequential daily immunization with exogenous antigen plus the TLR3 agonist poly(I:C) - Wick, Darin A.; Martin, Spencer D.; Nelson, Brad H.; Webb, John R. (Vaccine, 2011)
Keywords: Adjuvants, Immunologic - administration & dosage; agonists; Allergy and Immunology; Animals; Applied microbiology; Biological and medical sciences; CD8+ T cells; CD8-positive T-lymphocytes; CD8-Positive T-Lymphocytes - immunology; Cytokines - secretion; Enzyme-Linked Immunospot Assay; epitopes; Female; Fundamental and applied biological sciences. Psychology; Human papillomavirus 16; immunity; Immunization; Immunization - methods; Infections; Injections, Subcutaneous; Medical research; Mice; Mice, Inbred C57BL; Microbiology; neoplasms; Ovalbumin - administration & dosage; Ovalbumin - immunology; Papillomavirus E7 Proteins - administration & dosage; Papillomavirus E7 Proteins - immunology; Peptides; Poly I-C - administration & dosage; splenocytes; synthetic peptides; T cell receptors; TLR3; Toll-Like Receptor 3 - agonists; vaccination; Vaccine; vaccine development; Vaccines; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); Viral infections; CD8+ T cells; Vaccine; TLR3; CD8 + T cells; Antigen; Immunization; CD8; T cells; CD8 T lymphocyte