Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA
In metazoans, nuclear export of bulk mRNA is mediated by Tap‐p15, a conserved heterodimeric export receptor that cooperates with adaptor RNA‐binding proteins. In this article, we show that Thoc5, a subunit of the mammalian TREX complex, binds to a distinct surface on the middle (Ntf2‐like) domain of...
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| Published in | The EMBO journal Vol. 28; no. 5; pp. 556 - 567 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
Chichester, UK
John Wiley & Sons, Ltd
04.03.2009
Nature Publishing Group UK Blackwell Publishing Ltd Nature Publishing Group |
| Subjects | |
| Online Access | Get full text |
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| Abstract | In metazoans, nuclear export of bulk mRNA is mediated by Tap‐p15, a conserved heterodimeric export receptor that cooperates with adaptor RNA‐binding proteins. In this article, we show that Thoc5, a subunit of the mammalian TREX complex, binds to a distinct surface on the middle (Ntf2‐like) domain of Tap. Notably, adaptor protein Aly and Thoc5 can simultaneously bind to non‐overlapping binding sites on Tap‐p15.
In vivo
, Thoc5 was not required for bulk mRNA export. However, nuclear export of
HSP70
mRNA depends on both Thoc5 and Aly. Consistent with a function as a specific export adaptor, Thoc5 exhibits
in vitro
RNA‐binding activity and is associated with
HSP70
mRNPs
in vivo
as a component of the stable THO complex. Thus, through the combinatorial use of an adaptor (e.g., Aly) and co‐adapter (e.g., Thoc5), Tap‐p15 could function as an export receptor for different classes of mRNAs. |
|---|---|
| AbstractList | In metazoans, nuclear export of bulk mRNA is mediated by Tap-p15, a conserved heterodimeric export receptor that cooperates with adaptor RNA-binding proteins. In this article, we show that Thoc5, a subunit of the mammalian TREX complex, binds to a distinct surface on the middle (Ntf2-like) domain of Tap. Notably, adaptor protein Aly and Thoc5 can simultaneously bind to non-overlapping binding sites on Tap-p15. In vivo, Thoc5 was not required for bulk mRNA export. However, nuclear export of HSP70 mRNA depends on both Thoc5 and Aly. Consistent with a function as a specific export adaptor, Thoc5 exhibits in vitro RNA-binding activity and is associated with HSP70 mRNPs in vivo as a component of the stable THO complex. Thus, through the combinatorial use of an adaptor (e.g., Aly) and co-adapter (e.g., Thoc5), Tap-p15 could function as an export receptor for different classes of mRNAs. In metazoans, nuclear export of bulk mRNA is mediated by Tap-p15, a conserved heterodimeric export receptor that cooperates with adaptor RNA-binding proteins. In this article, we show that Thoc5, a subunit of the mammalian TREX complex, binds to a distinct surface on the middle (Ntf2-like) domain of Tap. Notably, adaptor protein Aly and Thoc5 can simultaneously bind to non-overlapping binding sites on Tap-p15. In vivo, Thoc5 was not required for bulk mRNA export. However, nuclear export of HSP70 mRNA depends on both Thoc5 and Aly. Consistent with a function as a specific export adaptor, Thoc5 exhibits in vitro RNA-binding activity and is associated with HSP70 mRNPs in vivo as a component of the stable THO complex. Thus, through the combinatorial use of an adaptor (e.g., Aly) and co-adapter (e.g., Thoc5), Tap-p15 could function as an export receptor for different classes of mRNAs. [PUBLICATION ABSTRACT] In metazoans, nuclear export of bulk mRNA is mediated by Tap-p15, a conserved heterodimeric export receptor that cooperates with adaptor RNA-binding proteins. In this article, we show that Thoc5, a subunit of the mammalian TREX complex, binds to a distinct surface on the middle (Ntf2-like) domain of Tap. Notably, adaptor protein Aly and Thoc5 can simultaneously bind to non-overlapping binding sites on Tap-p15. In vivo , Thoc5 was not required for bulk mRNA export. However, nuclear export of HSP70 mRNA depends on both Thoc5 and Aly. Consistent with a function as a specific export adaptor, Thoc5 exhibits in vitro RNA-binding activity and is associated with HSP70 mRNPs in vivo as a component of the stable THO complex. Thus, through the combinatorial use of an adaptor (e.g., Aly) and co-adapter (e.g., Thoc5), Tap-p15 could function as an export receptor for different classes of mRNAs. |
| Author | Katahira, Jun Inoue, Hitomi Yoneda, Yoshihiro Hurt, Ed |
| Author_xml | – sequence: 1 givenname: Jun surname: Katahira fullname: Katahira, Jun email: katahira@anat3.med.osaka-u.ac.jp organization: Biomolecular Networks Laboratories, Biomolecular Dynamics Laboratory, Graduate School of Frontier Biosciences, Osaka University, Yamadaoka, Suita, Osaka, Japan – sequence: 2 givenname: Hitomi surname: Inoue fullname: Inoue, Hitomi organization: Biomolecular Networks Laboratories, Biomolecular Dynamics Laboratory, Graduate School of Frontier Biosciences, Osaka University, Yamadaoka, Osaka, Suita, Japan – sequence: 3 givenname: Ed surname: Hurt fullname: Hurt, Ed organization: Biochemie-Zentrum der Universität Heidelberg (BZH), Im Neuenheimer Feld, Heidelberg, Germany – sequence: 4 givenname: Yoshihiro surname: Yoneda fullname: Yoneda, Yoshihiro email: katahira@anat3.med.osaka-u.ac.jp organization: Biomolecular Networks Laboratories, Biomolecular Dynamics Laboratory, Graduate School of Frontier Biosciences, Osaka University, Yamadaoka, Suita, Osaka, Japan |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/19165146$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1038/nature746 10.1073/pnas.031586198 10.1016/S1097-2765(04)00030-9 10.1093/emboj/18.9.2593 10.1093/nar/gkm347 10.1083/jcb.200207128 10.1083/jcb.150.4.695 10.1016/j.molcel.2007.02.018 10.1016/S0092-8674(02)00627-X 10.1261/rna.7154104 10.1016/j.ceb.2005.03.001 10.1083/jcb.200704174 10.1101/gad.10.13.1608 10.1002/j.1460-2075.1988.tb03227.x 10.1073/pnas.0403533101 10.1016/S0960-9822(01)00532-2 10.1101/gad.13.9.1126 10.1016/0092-8674(85)90286-7 10.1083/jcb.145.6.1133 10.1074/jbc.M700629200 10.1016/S0021-9258(17)30514-8 10.1016/S1097-2765(03)00089-3 10.1101/gad.1302205 10.1093/nar/gkm556 10.1261/rna.336807 10.1261/rna.5420503 10.1093/emboj/19.3.410 10.1016/S1097-2765(01)00348-3 10.1101/gad.1564807 10.1073/pnas.0308663100 10.1128/MCB.18.11.6826 10.1038/35098113 10.1101/gad.428407 10.1093/emboj/16.11.3256 10.1073/pnas.0506345103 10.1016/0092-8674(80)90559-0 10.1038/nrm2255 10.1016/j.ceb.2005.04.011 10.1038/sj.emboj.7600261 10.1038/nsmb759 10.1016/S1097-2765(00)80065-9 10.1177/002215549704501201 10.1093/nar/23.4.541 10.1128/MCB.20.23.8996-9008.2000 10.1093/emboj/19.21.5587 10.1038/35098106 10.1038/35030160 10.1093/hmg/2.9.1361 10.1128/MCB.01341-07 10.1074/jbc.M110007200 10.1101/gad.1503107 10.1038/sj.emboj.7601947 10.1016/0092-8674(86)90382-X 10.1017/S1355838200991994 10.1101/gad.1616008 10.1016/S0021-9258(19)36794-8 10.1017/S1355838200000078 10.1016/j.cell.2006.10.044 10.1101/gad.1506407 10.1002/j.1460-2075.1985.tb03891.x 10.1016/0092-8674(86)90464-2 10.1093/emboj/cdf335 10.1016/j.bbrc.2004.10.174 |
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| References | Hurt E, Luo MJ, Rother S, Reed R, Strasser K (2004) Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex. Proc Natl Acad Sci USA 101: 1858-1862 Chen YI, Moore RE, Ge HY, Young MK, Lee TD, Stevens SW (2007) Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors. Nucleic Acids Res 35: 3928-3944 Devos D, Dokudovskaya S, Williams R, Alber F, Eswar N, Chait BT, Rout MP, Sali A (2006) Simple fold composition and modular architecture of the nuclear pore complex. Proc Natl Acad Sci USA 103: 2172-2177 Katahira J, Strasser K, Saiwaki T, Yoneda Y, Hurt E (2002) Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling. J Biol Chem 277: 9242-9246 Strasser K, Basler J, Hurt E (2000) Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export. J Cell Biol 150: 695-706 Hernandez G, Vazquez-Pianzola P, Sierra JM, Rivera-Pomar R (2004) Internal ribosome entry site drives cap-independent translation of reaper and heat shock protein 70 mRNAs in Drosophila embryos. RNA 10: 1783-1797 Gilbert W, Guthrie C (2004) The Glc7p nuclear phosphatase promotes mRNA export by facilitating association of Mex67p with mRNA. Mol Cell 13: 201-212 Rother S, Strasser K (2007) The RNA polymerase II CTD kinase Ctk1 functions in translation elongation. Genes Dev 21: 1409-1421 Herold A, Klymenko T, Izaurralde E (2001) NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila. RNA 7: 1768-1780 Farny NG, Hurt JA, Silver PA (2008) Definition of global and transcript-specific mRNA export pathways in metazoans. Genes Dev 22: 66-78 Herold A, Suyama M, Rodrigues JP, Braun IC, Kutay U, Carmo-Fonseca M, Bork P, Izaurralde E (2000) TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture. Mol Cell Biol 20: 8996-9008 Bond U (1988) Heat shock but not other stress inducers leads to the disruption of a sub-set of snRNPs and inhibition of in vitro splicing in HeLa cells. EMBO J 7: 3509-3518 Zhou Z, Luo MJ, Strasser K, Katahira J, Hurt E, Reed R (2000) The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans. Nature 407: 401-405 Huang Y, Yario TA, Steitz JA (2004) A molecular link between SR protein dephosphorylation and mRNA export. Proc Natl Acad Sci USA 101: 9666-9670 Huang Y, Gattoni R, Stevenin J, Steitz JA (2003) SR splicing factors serve as adapter proteins for TAP-dependent mRNA export. Mol Cell 11: 837-843 Strasser K, Hurt E (2001) Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p. Nature 413: 648-652 Gatfield D, Izaurralde E (2002) REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export. J Cell Biol 159: 579-588 Joshi-Barve S, De Benedetti A, Rhoads RE (1992) Preferential translation of heat shock mRNAs in HeLa cells deficient in protein synthesis initiation factors eIF-4E and eIF-4 gamma. J Biol Chem 267: 21038-21043 Rehwinkel J, Herold A, Gari K, Kocher T, Rode M, Ciccarelli FL, Wilm M, Izaurralde E (2004) Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster. Nat Struct Mol Biol 11: 558-566 Katahira J, Miki T, Takano K, Maruhashi M, Uchikawa M, Tachibana T, Yoneda Y (2007) Nuclear RNA export factor 7 is localized in processing bodies and neuronal RNA granules through interactions with shuttling hnRNPs. Nucleic Acids Res 36: 616-628 Rodrigues JP, Rode M, Gatfield D, Blencowe B, Carmo-Fonseca M, Izaurralde E (2001) REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus. Proc Natl Acad Sci USA 98: 1030-1035 Jolly C, Vourc'h C, Robert-Nicoud M, Morimoto RI (1999) Intron-independent association of splicing factors with active genes. J Cell Biol 145: 1133-1143 Klemenz R, Hultmark D, Gehring WJ (1985) Selective translation of heat shock mRNA in Drosophila melanogaster depends on sequence information in the leader. EMBO J 4: 2053-2060 Yao W, Roser D, Kohler A, Bradatsch B, Bassler J, Hurt E (2007) Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2. Mol Cell 26: 51-62 Reed R, Hurt E (2002) A conserved mRNA export machinery coupled to pre-mRNA splicing. Cell 108: 523-531 McGarry TJ, Lindquist S (1985) The preferential translation of Drosophila hsp70 mRNA requires sequences in the untranslated leader. Cell 42: 903-911 Segref A, Sharma K, Doye V, Hellwig A, Huber J, Luhrmann R, Hurt E (1997) Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores. EMBO J 16: 3256-3271 Aguilera A (2005) Cotranscriptional mRNP assembly: from the DNA to the nuclear pore. Curr Opin Cell Biol 17: 242-250 Masuda S, Das R, Cheng H, Hurt E, Dorman N, Reed R (2005) Recruitment of the human TREX complex to mRNA during splicing. Genes Dev 19: 1512-1517 Gatfield D, Le Hir H, Schmitt C, Braun IC, Kocher T, Wilm M, Izaurralde E (2001) The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila. Curr Biol 11: 1716-1721 Jolly C, Mongelard F, Robert-Nicoud M, Vourc'h C (1997) Optimization of nuclear transcript detection by FISH and combination with fluorescence immunocytochemical detection of transcription factors. J Histochem Cytochem 45: 1585-1592 Longman D, Johnstone IL, Caceres JF (2003) The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans. RNA 9: 881-891 Gruter P, Tabernero C, von Kobbe C, Schmitt C, Saavedra C, Bachi A, Wilm M, Felber BK, Izaurralde E (1998) TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus. Mol Cell 1: 649-659 Luo ML, Zhou Z, Magni K, Christoforides C, Rappsilber J, Mann M, Reed R (2001) Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly. Nature 413: 644-647 Marr II MT, D'Alessio JA, Puig O, Tjian R (2007) IRES-mediated functional coupling of transcription and translation amplifies insulin receptor feedback. Genes Dev 21: 175-183 Kang Y, Cullen BR (1999) The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences. Genes Dev 13: 1126-1139 Yao W, Lutzmann M, Hurt E (2008) A versatile interaction platform on the Mex67-Mtr2 receptor creates an overlap between mRNA and ribosome export. EMBO J 27: 6-16 Yost HJ, Lindquist S (1986) RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis. Cell 45: 185-193 Xle YG, Han FY, Peyrard M, Ruttledge MH, Fransson I, DeJong P, Collins J, Dunham I, Nordenakjold M, Dumanski J (1993) Cloning of a novel, anonymous gene from a megabase-range YAC and cosmid contig in the neurofibromatosis type 2/meningioma region on human chromosome 22q12. Hum Mol Genet 2: 1361-1368 Saavedra C, Tung KS, Amberg DC, Hopper AK, Cole CN (1996) Regulation of mRNA export in response to stress in Saccharomyces cerevisiae. Genes Dev 10: 1608-1620 Hultmark D, Klemenz R, Gehring WJ (1986) Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22. Cell 44: 429-438 Fribourg S, Braun IC, Izaurralde E, Conti E (2001) Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear exprot factor. Mol Cell 8: 645-656 Nojima T, Hirose T, Kimura H, Hagiwara M (2007) The interaction between cap-binding complex and RNA export factor is required for intronless mRNA export. J Biol Chem 282: 15645-15651 Abruzzi KC, Lacadie S, Rosbash M (2004) Biochemical analysis of TREX complex recruitment to intronless and intron-containing yeast genes. EMBO J 23: 2620-2631 Cheng H, Dufu K, Lee CS, Hsu JL, Dias A, Reed R (2006) Human mRNA export machinery recruited to the 5′ end of mRNA. Cell 127: 1389-1400 Storti RV, Scott MP, Rich A, Pardue ML (1980) Translational control of protein synthesis in response to heat shock in D. melanogaster cells. Cell 22: 825-834 Katahira J, Strasser K, Podtelejnikov A, Mann M, Jung JU, Hurt E (1999) The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human. EMBO J 18: 2593-2609 Yoh SM, Cho H, Pickle L, Evans RM, Jones KA (2007) The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export. Genes Dev 21: 160-174 Joshi CP, Nguyen HT (1995) 5′ Untranslated leader sequences of eukaryotic mRNAs encoding heat shock induced proteins. Nucl Acids Res 23: 541-549 Strasser K, Masuda S, Mason P, Pfannstiel J, Oppizzi M, Rodriguez-Navarro S, Rondon AG, Aguilera A, Struhl K, Reed R, Hurt E (2002) TREX is a conserved complex coupling transcription with messenger RNA export. Nature 417: 304-308 Taniguchi I, Ohno M (2008) ATP-dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56. Mol Cell Biol 28: 601-608 Reed R, Cheng H (2005) TREX, SR proteins and export of mRNA. Curr Opin Cell Biol 17: 269-273 Hampsey M, Kinzy TG (2007) Synchronicity: policing multiple aspects of gene expression by Ctk1. Genes Dev 21: 1288-1291 Merz C, Urlaub H, Will CL, Luhrmann R (2007) Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. RNA 13: 116-128 Stutz F, Bachi A, Doerks T, Braun IC, Seraphin B, Wilm M, Bork P, Izaurralde E (2000) REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export. RNA 6: 638-650 Bachi A, Braun IC, Rodrigues JP, Pante N, Ribbeck K, von Kobbe C, Kutay U, Wilm M, Gorlich D, Carmo-Fonseca M, Izaurralde E (2000) The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates. RNA 6: 136-158 Liker E, Fernandez E, Izaurralde E, Conti E (2000) The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain. EMBO J 19: 5587-5598 Santos-Rosa H, Mo Gilbert, W, Guthrie, C (b12) 2004; 13 Farny, NG, Hurt, JA, Silver, PA (b8) 2008; 22 Nojima, T, Hirose, T, Kimura, H, Hagiwara, M (b41) 2007; 282 Segref, A, Sharma, K, Doye, V, Hellwig, A, Huber, J, Luhrmann, R, Hurt, E (b49) 1997; 16 Katahira, J, Strasser, K, Saiwaki, T, Yoneda, Y, Hurt, E (b30) 2002; 277 Katahira, J, Strasser, K, Podtelejnikov, A, Mann, M, Jung, JU, Hurt, E (b31) 1999; 18 Cheng, H, Dufu, K, Lee, CS, Hsu, JL, Dias, A, Reed, R (b6) 2006; 127 Strasser, K, Basler, J, Hurt, E (b52) 2000; 150 Yao, W, Roser, D, Kohler, A, Bradatsch, B, Bassler, J, Hurt, E (b61) 2007; 26 Terry, LJ, Wente, SR (b58) 2007; 178 Taniguchi, I, Ohno, M (b57) 2008; 28 Kang, Y, Cullen, BR (b28) 1999; 13 Hurt, E, Luo, MJ, Rother, S, Reed, R, Strasser, K (b22) 2004; 101 Devos, D, Dokudovskaya, S, Williams, R, Alber, F, Eswar, N, Chait, BT, Rout, MP, Sali, A (b7) 2006; 103 Zhou, Z, Luo, MJ, Strasser, K, Katahira, J, Hurt, E, Reed, R (b64) 2000; 407 Santos-Rosa, H, Moreno, H, Simos, G, Segref, A, Fahrenkrog, B, Pante, N, Hurt, E (b48) 1998; 18 Jolly, C, Mongelard, F, Robert-Nicoud, M, Vourc'h, C (b24) 1997; 45 Joshi, CP, Nguyen, HT (b26) 1995; 23 Fribourg, S, Braun, IC, Izaurralde, E, Conti, E (b9) 2001; 8 Strasser, K, Hurt, E (b54) 2001; 413 Yost, HJ, Lindquist, S (b63) 1986; 45 Huang, Y, Yario, TA, Steitz, JA (b20) 2004; 101 Stutz, F, Bachi, A, Doerks, T, Braun, IC, Seraphin, B, Wilm, M, Bork, P, Izaurralde, E (b56) 2000; 6 Shukla, RR, Dominski, Z, Zwierzynski, T, Kole, R (b50) 1990; 265 Yao, W, Lutzmann, M, Hurt, E (b60) 2008; 27 Xle, YG, Han, FY, Peyrard, M, Ruttledge, MH, Fransson, I, DeJong, P, Collins, J, Dunham, I, Nordenakjold, M, Dumanski, J (b59) 1993; 2 Gruter, P, Tabernero, C, von Kobbe, C, Schmitt, C, Saavedra, C, Bachi, A, Wilm, M, Felber, BK, Izaurralde, E (b13) 1998; 1 Strasser, K, Hurt, E (b53) 2000; 19 Bond, U (b4) 1988; 7 Kohler, A, Hurt, E (b33) 2007; 8 Liker, E, Fernandez, E, Izaurralde, E, Conti, E (b34) 2000; 19 Luo, ML, Zhou, Z, Magni, K, Christoforides, C, Rappsilber, J, Mann, M, Reed, R (b36) 2001; 413 Reed, R, Hurt, E (b43) 2002; 108 Herold, A, Suyama, M, Rodrigues, JP, Braun, IC, Kutay, U, Carmo-Fonseca, M, Bork, P, Izaurralde, E (b17) 2000; 20 Jolly, C, Vourc'h, C, Robert-Nicoud, M, Morimoto, RI (b25) 1999; 145 Bachi, A, Braun, IC, Rodrigues, JP, Pante, N, Ribbeck, K, von Kobbe, C, Kutay, U, Wilm, M, Gorlich, D, Carmo-Fonseca, M, Izaurralde, E (b3) 2000; 6 Gatfield, D, Le Hir, H, Schmitt, C, Braun, IC, Kocher, T, Wilm, M, Izaurralde, E (b11) 2001; 11 Chen, YI, Moore, RE, Ge, HY, Young, MK, Lee, TD, Stevens, SW (b5) 2007; 35 Horie-Inoue, K, Bono, H, Okazaki, Y, Inoue, S (b18) 2004; 325 Hultmark, D, Klemenz, R, Gehring, WJ (b21) 1986; 44 Storti, RV, Scott, MP, Rich, A, Pardue, ML (b51) 1980; 22 Klemenz, R, Hultmark, D, Gehring, WJ (b32) 1985; 4 Herold, A, Klymenko, T, Izaurralde, E (b16) 2001; 7 Masuda, S, Das, R, Cheng, H, Hurt, E, Dorman, N, Reed, R (b38) 2005; 19 McGarry, TJ, Lindquist, S (b39) 1985; 42 Katahira, J, Miki, T, Takano, K, Maruhashi, M, Uchikawa, M, Tachibana, T, Yoneda, Y (b29) 2007; 36 Abruzzi, KC, Lacadie, S, Rosbash, M (b1) 2004; 23 Yoh, SM, Cho, H, Pickle, L, Evans, RM, Jones, KA (b62) 2007; 21 Reed, R, Cheng, H (b42) 2005; 17 Gatfield, D, Izaurralde, E (b10) 2002; 159 Rodrigues, JP, Rode, M, Gatfield, D, Blencowe, B, Carmo-Fonseca, M, Izaurralde, E (b45) 2001; 98 Hampsey, M, Kinzy, TG (b14) 2007; 21 Jimeno, S, Rondon, AG, Luna, R, Aguilera, A (b23) 2002; 21 Marr, MT, D'Alessio, JA, Puig, O, Tjian, R (b37) 2007; 21 Rehwinkel, J, Herold, A, Gari, K, Kocher, T, Rode, M, Ciccarelli, FL, Wilm, M, Izaurralde, E (b44) 2004; 11 Hernandez, G, Vazquez-Pianzola, P, Sierra, JM, Rivera-Pomar, R (b15) 2004; 10 Rother, S, Strasser, K (b46) 2007; 21 Longman, D, Johnstone, IL, Caceres, JF (b35) 2003; 9 Merz, C, Urlaub, H, Will, CL, Luhrmann, R (b40) 2007; 13 Saavedra, C, Tung, KS, Amberg, DC, Hopper, AK, Cole, CN (b47) 1996; 10 Huang, Y, Gattoni, R, Stevenin, J, Steitz, JA (b19) 2003; 11 Strasser, K, Masuda, S, Mason, P, Pfannstiel, J, Oppizzi, M, Rodriguez-Navarro, S, Rondon, AG, Aguilera, A, Struhl, K, Reed, R, Hurt, E (b55) 2002; 417 Joshi-Barve, S, De Benedetti, A, Rhoads, RE (b27) 1992; 267 Aguilera, A (b2) 2005; 17 Aguilera (CR2) 2005; 17 Hampsey, Kinzy (CR14) 2007; 21 Fribourg, Braun, Izaurralde, Conti (CR9) 2001; 8 Kohler, Hurt (CR33) 2007; 8 Rodrigues, Rode, Gatfield, Blencowe, Carmo‐Fonseca, Izaurralde (CR45) 2001; 98 Taniguchi, Ohno (CR57) 2008; 28 Gruter, Tabernero, von Kobbe, Schmitt, Saavedra, Bachi, Wilm, Felber, Izaurralde (CR13) 1998; 1 Farny, Hurt, Silver (CR8) 2008; 22 Hurt, Luo, Rother, Reed, Strasser (CR22) 2004; 101 Hultmark, Klemenz, Gehring (CR21) 1986; 44 Gatfield, Le Hir, Schmitt, Braun, Kocher, Wilm, Izaurralde (CR11) 2001; 11 Hernandez, Vazquez‐Pianzola, Sierra, Rivera‐Pomar (CR15) 2004; 10 Yoh, Cho, Pickle, Evans, Jones (CR62) 2007; 21 Strasser, Hurt (CR53) 2000; 19 Yao, Lutzmann, Hurt (CR60) 2008; 27 Jolly, Vourc'h, Robert‐Nicoud, Morimoto (CR25) 1999; 145 Huang, Yario, Steitz (CR20) 2004; 101 Reed, Cheng (CR42) 2005; 17 Yao, Roser, Kohler, Bradatsch, Bassler, Hurt (CR61) 2007; 26 Katahira, Strasser, Saiwaki, Yoneda, Hurt (CR30) 2002; 277 Horie‐Inoue, Bono, Okazaki, Inoue (CR18) 2004; 325 Marr II, D'Alessio, Puig, Tjian (CR37) 2007; 21 Gilbert, Guthrie (CR12) 2004; 13 Jimeno, Rondon, Luna, Aguilera (CR23) 2002; 21 Herold, Klymenko, Izaurralde (CR16) 2001; 7 Reed, Hurt (CR43) 2002; 108 Strasser, Basler, Hurt (CR52) 2000; 150 Gatfield, Izaurralde (CR10) 2002; 159 Huang, Gattoni, Stevenin, Steitz (CR19) 2003; 11 Yost, Lindquist (CR63) 1986; 45 Bond (CR4) 1988; 7 Longman, Johnstone, Caceres (CR35) 2003; 9 Luo, Zhou, Magni, Christoforides, Rappsilber, Mann, Reed (CR36) 2001; 413 Saavedra, Tung, Amberg, Hopper, Cole (CR47) 1996; 10 McGarry, Lindquist (CR39) 1985; 42 Bachi, Braun, Rodrigues, Pante, Ribbeck, von Kobbe, Kutay, Wilm, Gorlich, Carmo‐Fonseca, Izaurralde (CR3) 2000; 6 Terry, Wente (CR58) 2007; 178 Rehwinkel, Herold, Gari, Kocher, Rode, Ciccarelli, Wilm, Izaurralde (CR44) 2004; 11 Klemenz, Hultmark, Gehring (CR32) 1985; 4 Strasser, Hurt (CR54) 2001; 413 Chen, Moore, Ge, Young, Lee, Stevens (CR5) 2007; 35 Jolly, Mongelard, Robert‐Nicoud, Vourc'h (CR24) 1997; 45 Shukla, Dominski, Zwierzynski, Kole (CR50) 1990; 265 Masuda, Das, Cheng, Hurt, Dorman, Reed (CR38) 2005; 19 Joshi‐Barve, De Benedetti, Rhoads (CR27) 1992; 267 Santos‐Rosa, Moreno, Simos, Segref, Fahrenkrog, Pante, Hurt (CR48) 1998; 18 Storti, Scott, Rich, Pardue (CR51) 1980; 22 Abruzzi, Lacadie, Rosbash (CR1) 2004; 23 Rother, Strasser (CR46) 2007; 21 Joshi, Nguyen (CR26) 1995; 23 Herold, Suyama, Rodrigues, Braun, Kutay, Carmo‐Fonseca, Bork, Izaurralde (CR17) 2000; 20 Stutz, Bachi, Doerks, Braun, Seraphin, Wilm, Bork, Izaurralde (CR56) 2000; 6 Kang, Cullen (CR28) 1999; 13 Katahira, Miki, Takano, Maruhashi, Uchikawa, Tachibana, Yoneda (CR29) 2007; 36 Zhou, Luo, Strasser, Katahira, Hurt, Reed (CR64) 2000; 407 Strasser, Masuda, Mason, Pfannstiel, Oppizzi, Rodriguez‐Navarro, Rondon, Aguilera, Struhl, Reed, Hurt (CR55) 2002; 417 Nojima, Hirose, Kimura, Hagiwara (CR41) 2007; 282 Segref, Sharma, Doye, Hellwig, Huber, Luhrmann, Hurt (CR49) 1997; 16 Merz, Urlaub, Will, Luhrmann (CR40) 2007; 13 Xle, Han, Peyrard, Ruttledge, Fransson, DeJong, Collins, Dunham, Nordenakjold, Dumanski (CR59) 1993; 2 Devos, Dokudovskaya, Williams, Alber, Eswar, Chait, Rout, Sali (CR7) 2006; 103 Liker, Fernandez, Izaurralde, Conti (CR34) 2000; 19 Cheng, Dufu, Lee, Hsu, Dias, Reed (CR6) 2006; 127 Katahira, Strasser, Podtelejnikov, Mann, Jung, Hurt (CR31) 1999; 18 2004; 325 2000; 6 2004; 23 1997; 45 2002; 277 2002; 159 1990; 265 1993; 2 2007; 35 2007; 36 2003; 11 2000; 407 1998; 18 2007; 178 2000; 19 1986; 44 1999; 18 1986; 45 1995; 23 2008; 27 2003; 9 2008; 28 1999; 13 2007; 8 1997; 16 2008; 22 2002; 108 2006; 127 2001; 11 2007; 21 2007; 26 2001; 413 2001; 98 2004; 101 2007; 282 1985; 4 1992; 267 1980; 22 2000; 20 2000; 150 1999; 145 2002; 417 1985; 42 2007; 13 1996; 10 2004; 10 2004; 11 2005; 19 2001; 7 2002; 21 1988; 7 2001; 8 2004; 13 1998; 1 2005; 17 2006; 103 15210956 - Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9666-70 12667464 - Mol Cell. 2003 Mar;11(3):837-43 17545464 - Genes Dev. 2007 Jun 1;21(11):1288-91 2933251 - EMBO J. 1985 Aug;4(8):2053-60 2421918 - Cell. 1986 Apr 25;45(2):185-93 17545469 - Genes Dev. 2007 Jun 1;21(11):1409-21 10323864 - Genes Dev. 1999 May 1;13(9):1126-39 10668806 - RNA. 2000 Jan;6(1):136-58 11909523 - Cell. 2002 Feb 22;108(4):523-31 15901492 - Curr Opin Cell Biol. 2005 Jun;17(3):242-50 7899073 - Nucleic Acids Res. 1995 Feb 25;23(4):541-9 14759366 - Mol Cell. 2004 Jan 30;13(2):201-12 15192704 - EMBO J. 2004 Jul 7;23(13):2620-31 11014198 - Nature. 2000 Sep 21;407(6802):401-5 11073998 - Mol Cell Biol. 2000 Dec;20(23):8996-9008 15133499 - Nat Struct Mol Biol. 2004 Jun;11(6):558-66 17434126 - Mol Cell. 2007 Apr 13;26(1):51-62 9389761 - J Histochem Cytochem. 1997 Dec;45(12):1585-92 15998806 - Genes Dev. 2005 Jul 1;19(13):1512-7 15555570 - Biochem Biophys Res Commun. 2004 Dec 24;325(4):1312-7 17984224 - Mol Cell Biol. 2008 Jan;28(2):601-8 11979277 - Nature. 2002 May 16;417(6886):304-8 11696332 - Curr Biol. 2001 Oct 30;11(21):1716-21 2147023 - J Biol Chem. 1990 Nov 25;265(33):20377-83 2974799 - EMBO J. 1988 Nov;7(11):3509-18 17190602 - Cell. 2006 Dec 29;127(7):1389-400 10366587 - J Cell Biol. 1999 Jun 14;145(6):1133-43 17234882 - Genes Dev. 2007 Jan 15;21(2):160-74 11675790 - Nature. 2001 Oct 11;413(6856):648-52 11583626 - Mol Cell. 2001 Sep;8(3):645-56 9214641 - EMBO J. 1997 Jun 2;16(11):3256-71 16461911 - Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2172-7 3943132 - Cell. 1986 Feb 14;44(3):429-38 10228171 - EMBO J. 1999 May 4;18(9):2593-609 18086857 - Genes Dev. 2008 Jan 1;22(1):66-78 12810921 - RNA. 2003 Jul;9(7):881-91 17363367 - J Biol Chem. 2007 May 25;282(21):15645-51 17095540 - RNA. 2007 Jan;13(1):116-28 4053186 - Cell. 1985 Oct;42(3):903-11 12093753 - EMBO J. 2002 Jul 1;21(13):3526-35 15496524 - RNA. 2004 Nov;10(11):1783-97 12438415 - J Cell Biol. 2002 Nov 25;159(4):579-88 15901496 - Curr Opin Cell Biol. 2005 Jun;17(3):269-73 18063567 - Nucleic Acids Res. 2008 Feb;36(2):616-28 17537823 - Nucleic Acids Res. 2007;35(12):3928-44 18046452 - EMBO J. 2008 Jan 9;27(1):6-16 11780633 - RNA. 2001 Dec;7(12):1768-80 17875746 - J Cell Biol. 2007 Sep 24;178(7):1121-32 11158589 - Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1030-5 6780199 - Cell. 1980 Dec;22(3):825-34 11675789 - Nature. 2001 Oct 11;413(6856):644-7 8682292 - Genes Dev. 1996 Jul 1;10(13):1608-20 9774696 - Mol Cell Biol. 1998 Nov;18(11):6826-38 11060011 - EMBO J. 2000 Nov 1;19(21):5587-98 17786152 - Nat Rev Mol Cell Biol. 2007 Oct;8(10):761-73 1400417 - J Biol Chem. 1992 Oct 15;267(29):21038-43 14769921 - Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1858-62 10722314 - EMBO J. 2000 Feb 1;19(3):410-20 9660949 - Mol Cell. 1998 Apr;1(5):649-59 10786854 - RNA. 2000 Apr;6(4):638-50 17234883 - Genes Dev. 2007 Jan 15;21(2):175-83 8242058 - Hum Mol Genet. 1993 Sep;2(9):1361-8 11756420 - J Biol Chem. 2002 Mar 15;277(11):9242-6 10952996 - J Cell Biol. 2000 Aug 21;150(4):695-706 Shukla RR (emboj20095-b50) 1990; 265 emboj20095-b42 emboj20095-b43 emboj20095-b44 emboj20095-b45 emboj20095-b40 emboj20095-b41 emboj20095-b46 emboj20095-b47 emboj20095-b49 Herold A (emboj20095-b16) 2001; 7 Klemenz R (emboj20095-b32) 1985; 4 emboj20095-b31 emboj20095-b33 emboj20095-b34 emboj20095-b30 emboj20095-b39 emboj20095-b35 emboj20095-b36 emboj20095-b37 emboj20095-b38 emboj20095-b20 emboj20095-b64 emboj20095-b21 emboj20095-b22 emboj20095-b23 emboj20095-b60 emboj20095-b61 emboj20095-b62 emboj20095-b63 emboj20095-b7 emboj20095-b28 emboj20095-b6 emboj20095-b29 emboj20095-b9 emboj20095-b8 emboj20095-b25 emboj20095-b26 Jolly C (emboj20095-b24) 1997; 45 emboj20095-b1 emboj20095-b3 emboj20095-b2 emboj20095-b5 Santos-Rosa H (emboj20095-b48) 1998; 18 Bond U (emboj20095-b4) 1988; 7 emboj20095-b53 emboj20095-b10 emboj20095-b54 emboj20095-b11 emboj20095-b55 emboj20095-b12 emboj20095-b56 emboj20095-b51 emboj20095-b52 emboj20095-b17 emboj20095-b18 emboj20095-b19 emboj20095-b13 emboj20095-b57 emboj20095-b14 emboj20095-b58 emboj20095-b15 emboj20095-b59 Joshi-Barve S (emboj20095-b27) 1992; 267 |
| References_xml | – volume: 10 start-page: 1608 year: 1996 end-page: 1620 ident: b47 publication-title: Genes Dev contributor: fullname: Cole, CN – volume: 19 start-page: 1512 year: 2005 end-page: 1517 ident: b38 publication-title: Genes Dev contributor: fullname: Reed, R – volume: 282 start-page: 15645 year: 2007 end-page: 15651 ident: b41 publication-title: J Biol Chem contributor: fullname: Hagiwara, M – volume: 11 start-page: 558 year: 2004 end-page: 566 ident: b44 publication-title: Nat Struct Mol Biol contributor: fullname: Izaurralde, E – volume: 413 start-page: 644 year: 2001 end-page: 647 ident: b36 publication-title: Nature contributor: fullname: Reed, R – volume: 11 start-page: 837 year: 2003 end-page: 843 ident: b19 publication-title: Mol Cell contributor: fullname: Steitz, JA – volume: 265 start-page: 20377 year: 1990 end-page: 20383 ident: b50 publication-title: J Biol Chem contributor: fullname: Kole, R – volume: 98 start-page: 1030 year: 2001 end-page: 1035 ident: b45 publication-title: Proc Natl Acad Sci USA contributor: fullname: Izaurralde, E – volume: 413 start-page: 648 year: 2001 end-page: 652 ident: b54 publication-title: Nature contributor: fullname: Hurt, E – volume: 42 start-page: 903 year: 1985 end-page: 911 ident: b39 publication-title: Cell contributor: fullname: Lindquist, S – volume: 21 start-page: 1288 year: 2007 end-page: 1291 ident: b14 publication-title: Genes Dev contributor: fullname: Kinzy, TG – volume: 45 start-page: 1585 year: 1997 end-page: 1592 ident: b24 publication-title: J Histochem Cytochem contributor: fullname: Vourc'h, C – volume: 6 start-page: 136 year: 2000 end-page: 158 ident: b3 publication-title: RNA contributor: fullname: Izaurralde, E – volume: 7 start-page: 1768 year: 2001 end-page: 1780 ident: b16 publication-title: RNA contributor: fullname: Izaurralde, E – volume: 8 start-page: 645 year: 2001 end-page: 656 ident: b9 publication-title: Mol Cell contributor: fullname: Conti, E – volume: 17 start-page: 242 year: 2005 end-page: 250 ident: b2 publication-title: Curr Opin Cell Biol contributor: fullname: Aguilera, A – volume: 277 start-page: 9242 year: 2002 end-page: 9246 ident: b30 publication-title: J Biol Chem contributor: fullname: Hurt, E – volume: 101 start-page: 1858 year: 2004 end-page: 1862 ident: b22 publication-title: Proc Natl Acad Sci USA contributor: fullname: Strasser, K – volume: 10 start-page: 1783 year: 2004 end-page: 1797 ident: b15 publication-title: RNA contributor: fullname: Rivera-Pomar, R – volume: 18 start-page: 2593 year: 1999 end-page: 2609 ident: b31 publication-title: EMBO J contributor: fullname: Hurt, E – volume: 27 start-page: 6 year: 2008 end-page: 16 ident: b60 publication-title: EMBO J contributor: fullname: Hurt, E – volume: 178 start-page: 1121 year: 2007 end-page: 1132 ident: b58 publication-title: J Cell Biol contributor: fullname: Wente, SR – volume: 7 start-page: 3509 year: 1988 end-page: 3518 ident: b4 publication-title: EMBO J contributor: fullname: Bond, U – volume: 22 start-page: 66 year: 2008 end-page: 78 ident: b8 publication-title: Genes Dev contributor: fullname: Silver, PA – volume: 159 start-page: 579 year: 2002 end-page: 588 ident: b10 publication-title: J Cell Biol contributor: fullname: Izaurralde, E – volume: 325 start-page: 1312 year: 2004 end-page: 1317 ident: b18 publication-title: Biochem Biophys Res Commun contributor: fullname: Inoue, S – volume: 19 start-page: 5587 year: 2000 end-page: 5598 ident: b34 publication-title: EMBO J contributor: fullname: Conti, E – volume: 18 start-page: 6826 year: 1998 end-page: 6838 ident: b48 publication-title: Mol Cell Biol contributor: fullname: Hurt, E – volume: 35 start-page: 3928 year: 2007 end-page: 3944 ident: b5 publication-title: Nucleic Acids Res contributor: fullname: Stevens, SW – volume: 21 start-page: 175 year: 2007 end-page: 183 ident: b37 publication-title: Genes Dev contributor: fullname: Tjian, R – volume: 101 start-page: 9666 year: 2004 end-page: 9670 ident: b20 publication-title: Proc Natl Acad Sci USA contributor: fullname: Steitz, JA – volume: 108 start-page: 523 year: 2002 end-page: 531 ident: b43 publication-title: Cell contributor: fullname: Hurt, E – volume: 2 start-page: 1361 year: 1993 end-page: 1368 ident: b59 publication-title: Hum Mol Genet contributor: fullname: Dumanski, J – volume: 407 start-page: 401 year: 2000 end-page: 405 ident: b64 publication-title: Nature contributor: fullname: Reed, R – volume: 417 start-page: 304 year: 2002 end-page: 308 ident: b55 publication-title: Nature contributor: fullname: Hurt, E – volume: 26 start-page: 51 year: 2007 end-page: 62 ident: b61 publication-title: Mol Cell contributor: fullname: Hurt, E – volume: 267 start-page: 21038 year: 1992 end-page: 21043 ident: b27 publication-title: J Biol Chem contributor: fullname: Rhoads, RE – volume: 44 start-page: 429 year: 1986 end-page: 438 ident: b21 publication-title: Cell contributor: fullname: Gehring, WJ – volume: 150 start-page: 695 year: 2000 end-page: 706 ident: b52 publication-title: J Cell Biol contributor: fullname: Hurt, E – volume: 6 start-page: 638 year: 2000 end-page: 650 ident: b56 publication-title: RNA contributor: fullname: Izaurralde, E – volume: 45 start-page: 185 year: 1986 end-page: 193 ident: b63 publication-title: Cell contributor: fullname: Lindquist, S – volume: 103 start-page: 2172 year: 2006 end-page: 2177 ident: b7 publication-title: Proc Natl Acad Sci USA contributor: fullname: Sali, A – volume: 36 start-page: 616 year: 2007 end-page: 628 ident: b29 publication-title: Nucleic Acids Res contributor: fullname: Yoneda, Y – volume: 4 start-page: 2053 year: 1985 end-page: 2060 ident: b32 publication-title: EMBO J contributor: fullname: Gehring, WJ – volume: 19 start-page: 410 year: 2000 end-page: 420 ident: b53 publication-title: EMBO J contributor: fullname: Hurt, E – volume: 22 start-page: 825 year: 1980 end-page: 834 ident: b51 publication-title: Cell contributor: fullname: Pardue, ML – volume: 21 start-page: 160 year: 2007 end-page: 174 ident: b62 publication-title: Genes Dev contributor: fullname: Jones, KA – volume: 145 start-page: 1133 year: 1999 end-page: 1143 ident: b25 publication-title: J Cell Biol contributor: fullname: Morimoto, RI – volume: 9 start-page: 881 year: 2003 end-page: 891 ident: b35 publication-title: RNA contributor: fullname: Caceres, JF – volume: 23 start-page: 541 year: 1995 end-page: 549 ident: b26 publication-title: Nucl Acids Res contributor: fullname: Nguyen, HT – volume: 11 start-page: 1716 year: 2001 end-page: 1721 ident: b11 publication-title: Curr Biol contributor: fullname: Izaurralde, E – volume: 1 start-page: 649 year: 1998 end-page: 659 ident: b13 publication-title: Mol Cell contributor: fullname: Izaurralde, E – volume: 13 start-page: 201 year: 2004 end-page: 212 ident: b12 publication-title: Mol Cell contributor: fullname: Guthrie, C – volume: 17 start-page: 269 year: 2005 end-page: 273 ident: b42 publication-title: Curr Opin Cell Biol contributor: fullname: Cheng, H – volume: 21 start-page: 1409 year: 2007 end-page: 1421 ident: b46 publication-title: Genes Dev contributor: fullname: Strasser, K – volume: 20 start-page: 8996 year: 2000 end-page: 9008 ident: b17 publication-title: Mol Cell Biol contributor: fullname: Izaurralde, E – volume: 13 start-page: 1126 year: 1999 end-page: 1139 ident: b28 publication-title: Genes Dev contributor: fullname: Cullen, BR – volume: 28 start-page: 601 year: 2008 end-page: 608 ident: b57 publication-title: Mol Cell Biol contributor: fullname: Ohno, M – volume: 23 start-page: 2620 year: 2004 end-page: 2631 ident: b1 publication-title: EMBO J contributor: fullname: Rosbash, M – volume: 127 start-page: 1389 year: 2006 end-page: 1400 ident: b6 publication-title: Cell contributor: fullname: Reed, R – volume: 8 start-page: 761 year: 2007 end-page: 773 ident: b33 publication-title: Nat Rev Mol Cell Biol contributor: fullname: Hurt, E – volume: 13 start-page: 116 year: 2007 end-page: 128 ident: b40 publication-title: RNA contributor: fullname: Luhrmann, R – volume: 16 start-page: 3256 year: 1997 end-page: 3271 ident: b49 publication-title: EMBO J contributor: fullname: Hurt, E – volume: 21 start-page: 3526 year: 2002 end-page: 3535 ident: b23 publication-title: EMBO J contributor: fullname: Aguilera, A – volume: 19 start-page: 1512 year: 2005 end-page: 1517 ident: CR38 article-title: Recruitment of the human TREX complex to mRNA during splicing publication-title: Genes Dev contributor: fullname: Reed – volume: 16 start-page: 3256 year: 1997 end-page: 3271 ident: CR49 article-title: Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores publication-title: EMBO J contributor: fullname: Hurt – volume: 45 start-page: 185 year: 1986 end-page: 193 ident: CR63 article-title: RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis publication-title: Cell contributor: fullname: Lindquist – volume: 6 start-page: 136 year: 2000 end-page: 158 ident: CR3 article-title: The C‐terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE‐bearing RNA substrates publication-title: RNA contributor: fullname: Izaurralde – volume: 22 start-page: 825 year: 1980 end-page: 834 ident: CR51 article-title: Translational control of protein synthesis in response to heat shock in cells publication-title: Cell contributor: fullname: Pardue – volume: 10 start-page: 1783 year: 2004 end-page: 1797 ident: CR15 article-title: Internal ribosome entry site drives cap‐independent translation of reaper and heat shock protein 70 mRNAs in embryos publication-title: RNA contributor: fullname: Rivera‐Pomar – volume: 7 start-page: 3509 year: 1988 end-page: 3518 ident: CR4 article-title: Heat shock but not other stress inducers leads to the disruption of a sub‐set of snRNPs and inhibition of splicing in HeLa cells publication-title: EMBO J contributor: fullname: Bond – volume: 417 start-page: 304 year: 2002 end-page: 308 ident: CR55 article-title: TREX is a conserved complex coupling transcription with messenger RNA export publication-title: Nature contributor: fullname: Hurt – volume: 44 start-page: 429 year: 1986 end-page: 438 ident: CR21 article-title: Translational and transcriptional control elements in the untranslated leader of the heat‐shock gene hsp22 publication-title: Cell contributor: fullname: Gehring – volume: 11 start-page: 837 year: 2003 end-page: 843 ident: CR19 article-title: SR splicing factors serve as adapter proteins for TAP‐dependent mRNA export publication-title: Mol Cell contributor: fullname: Steitz – volume: 45 start-page: 1585 year: 1997 end-page: 1592 ident: CR24 article-title: Optimization of nuclear transcript detection by FISH and combination with fluorescence immunocytochemical detection of transcription factors publication-title: J Histochem Cytochem contributor: fullname: Vourc'h – volume: 101 start-page: 9666 year: 2004 end-page: 9670 ident: CR20 article-title: A molecular link between SR protein dephosphorylation and mRNA export publication-title: Proc Natl Acad Sci USA contributor: fullname: Steitz – volume: 265 start-page: 20377 year: 1990 end-page: 20383 ident: CR50 article-title: Inactivation of splicing factors in HeLa cells subjected to heat shock publication-title: J Biol Chem contributor: fullname: Kole – volume: 7 start-page: 1768 year: 2001 end-page: 1780 ident: CR16 article-title: NXF1/p15 heterodimers are essential for mRNA nuclear export in publication-title: RNA contributor: fullname: Izaurralde – volume: 282 start-page: 15645 year: 2007 end-page: 15651 ident: CR41 article-title: The interaction between cap‐binding complex and RNA export factor is required for intronless mRNA export publication-title: J Biol Chem contributor: fullname: Hagiwara – volume: 2 start-page: 1361 year: 1993 end-page: 1368 ident: CR59 article-title: Cloning of a novel, anonymous gene from a megabase‐range YAC and cosmid contig in the neurofibromatosis type 2/meningioma region on human chromosome 22q12 publication-title: Hum Mol Genet contributor: fullname: Dumanski – volume: 101 start-page: 1858 year: 2004 end-page: 1862 ident: CR22 article-title: Cotranscriptional recruitment of the serine‐arginine‐rich (SR)‐like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex publication-title: Proc Natl Acad Sci USA contributor: fullname: Strasser – volume: 127 start-page: 1389 year: 2006 end-page: 1400 ident: CR6 article-title: Human mRNA export machinery recruited to the 5′ end of mRNA publication-title: Cell contributor: fullname: Reed – volume: 23 start-page: 541 year: 1995 end-page: 549 ident: CR26 article-title: 5′ Untranslated leader sequences of eukaryotic mRNAs encoding heat shock induced proteins publication-title: Nucl Acids Res contributor: fullname: Nguyen – volume: 8 start-page: 645 year: 2001 end-page: 656 ident: CR9 article-title: Structural basis for the recognition of a nucleoporin FG repeat by the NTF2‐like domain of the TAP/p15 mRNA nuclear exprot factor publication-title: Mol Cell contributor: fullname: Conti – volume: 17 start-page: 242 year: 2005 end-page: 250 ident: CR2 article-title: Cotranscriptional mRNP assembly: from the DNA to the nuclear pore publication-title: Curr Opin Cell Biol contributor: fullname: Aguilera – volume: 11 start-page: 1716 year: 2001 end-page: 1721 ident: CR11 article-title: The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in publication-title: Curr Biol contributor: fullname: Izaurralde – volume: 4 start-page: 2053 year: 1985 end-page: 2060 ident: CR32 article-title: Selective translation of heat shock mRNA in depends on sequence information in the leader publication-title: EMBO J contributor: fullname: Gehring – volume: 21 start-page: 1288 year: 2007 end-page: 1291 ident: CR14 article-title: Synchronicity: policing multiple aspects of gene expression by Ctk1 publication-title: Genes Dev contributor: fullname: Kinzy – volume: 98 start-page: 1030 year: 2001 end-page: 1035 ident: CR45 article-title: REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus publication-title: Proc Natl Acad Sci USA contributor: fullname: Izaurralde – volume: 28 start-page: 601 year: 2008 end-page: 608 ident: CR57 article-title: ATP‐dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56 publication-title: Mol Cell Biol contributor: fullname: Ohno – volume: 21 start-page: 3526 year: 2002 end-page: 3535 ident: CR23 article-title: The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability publication-title: EMBO J contributor: fullname: Aguilera – volume: 159 start-page: 579 year: 2002 end-page: 588 ident: CR10 article-title: REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export publication-title: J Cell Biol contributor: fullname: Izaurralde – volume: 9 start-page: 881 year: 2003 end-page: 891 ident: CR35 article-title: The Ref/Aly proteins are dispensable for mRNA export and development in publication-title: RNA contributor: fullname: Caceres – volume: 1 start-page: 649 year: 1998 end-page: 659 ident: CR13 article-title: TAP, the human homolog of Mex67p, mediates CTE‐dependent RNA export from the nucleus publication-title: Mol Cell contributor: fullname: Izaurralde – volume: 13 start-page: 1126 year: 1999 end-page: 1139 ident: CR28 article-title: The human Tap protein is a nuclear mRNA export factor that contains novel RNA‐binding and nucleocytoplasmic transport sequences publication-title: Genes Dev contributor: fullname: Cullen – volume: 145 start-page: 1133 year: 1999 end-page: 1143 ident: CR25 article-title: Intron‐independent association of splicing factors with active genes publication-title: J Cell Biol contributor: fullname: Morimoto – volume: 18 start-page: 6826 year: 1998 end-page: 6838 ident: CR48 article-title: Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores publication-title: Mol Cell Biol contributor: fullname: Hurt – volume: 108 start-page: 523 year: 2002 end-page: 531 ident: CR43 article-title: A conserved mRNA export machinery coupled to pre‐mRNA splicing publication-title: Cell contributor: fullname: Hurt – volume: 103 start-page: 2172 year: 2006 end-page: 2177 ident: CR7 article-title: Simple fold composition and modular architecture of the nuclear pore complex publication-title: Proc Natl Acad Sci USA contributor: fullname: Sali – volume: 36 start-page: 616 year: 2007 end-page: 628 ident: CR29 article-title: Nuclear RNA export factor 7 is localized in processing bodies and neuronal RNA granules through interactions with shuttling hnRNPs publication-title: Nucleic Acids Res contributor: fullname: Yoneda – volume: 413 start-page: 644 year: 2001 end-page: 647 ident: CR36 article-title: Pre‐mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly publication-title: Nature contributor: fullname: Reed – volume: 21 start-page: 175 year: 2007 end-page: 183 ident: CR37 article-title: IRES‐mediated functional coupling of transcription and translation amplifies insulin receptor feedback publication-title: Genes Dev contributor: fullname: Tjian – volume: 23 start-page: 2620 year: 2004 end-page: 2631 ident: CR1 article-title: Biochemical analysis of TREX complex recruitment to intronless and intron‐containing yeast genes publication-title: EMBO J contributor: fullname: Rosbash – volume: 19 start-page: 410 year: 2000 end-page: 420 ident: CR53 article-title: Yra1p, a conserved nuclear RNA‐binding protein, interacts directly with Mex67p and is required for mRNA export publication-title: EMBO J contributor: fullname: Hurt – volume: 27 start-page: 6 year: 2008 end-page: 16 ident: CR60 article-title: A versatile interaction platform on the Mex67‐Mtr2 receptor creates an overlap between mRNA and ribosome export publication-title: EMBO J contributor: fullname: Hurt – volume: 13 start-page: 201 year: 2004 end-page: 212 ident: CR12 article-title: The Glc7p nuclear phosphatase promotes mRNA export by facilitating association of Mex67p with mRNA publication-title: Mol Cell contributor: fullname: Guthrie – volume: 267 start-page: 21038 year: 1992 end-page: 21043 ident: CR27 article-title: Preferential translation of heat shock mRNAs in HeLa cells deficient in protein synthesis initiation factors eIF‐4E and eIF‐4 gamma publication-title: J Biol Chem contributor: fullname: Rhoads – volume: 13 start-page: 116 year: 2007 end-page: 128 ident: CR40 article-title: Protein composition of human mRNPs spliced and differential requirements for mRNP protein recruitment publication-title: RNA contributor: fullname: Luhrmann – volume: 413 start-page: 648 year: 2001 end-page: 652 ident: CR54 article-title: Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p publication-title: Nature contributor: fullname: Hurt – volume: 407 start-page: 401 year: 2000 end-page: 405 ident: CR64 article-title: The protein Aly links pre‐messenger‐RNA splicing to nuclear export in metazoans publication-title: Nature contributor: fullname: Reed – volume: 8 start-page: 761 year: 2007 end-page: 773 ident: CR33 article-title: Exporting RNA from the nucleus to the cytoplasm publication-title: Nat Rev Mol Cell Biol contributor: fullname: Hurt – volume: 178 start-page: 1121 year: 2007 end-page: 1132 ident: CR58 article-title: Nuclear mRNA export requires specific FG nucleoporins for translocation through the nuclear pore complex publication-title: J Cell Biol contributor: fullname: Wente – volume: 35 start-page: 3928 year: 2007 end-page: 3944 ident: CR5 article-title: Proteomic analysis of ‐assembled pre‐mRNA splicing complexes expands the catalog of participating factors publication-title: Nucleic Acids Res contributor: fullname: Stevens – volume: 20 start-page: 8996 year: 2000 end-page: 9008 ident: CR17 article-title: TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture publication-title: Mol Cell Biol contributor: fullname: Izaurralde – volume: 150 start-page: 695 year: 2000 end-page: 706 ident: CR52 article-title: Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export publication-title: J Cell Biol contributor: fullname: Hurt – volume: 19 start-page: 5587 year: 2000 end-page: 5598 ident: CR34 article-title: The structure of the mRNA export factor TAP reveals a arrangement of a non‐canonical RNP domain and an LRR domain publication-title: EMBO J contributor: fullname: Conti – volume: 21 start-page: 1409 year: 2007 end-page: 1421 ident: CR46 article-title: The RNA polymerase II CTD kinase Ctk1 functions in translation elongation publication-title: Genes Dev contributor: fullname: Strasser – volume: 277 start-page: 9242 year: 2002 end-page: 9246 ident: CR30 article-title: Complex formation between Tap and p15 affects binding to FG‐repeat nucleoporins and nucleocytoplasmic shuttling publication-title: J Biol Chem contributor: fullname: Hurt – volume: 6 start-page: 638 year: 2000 end-page: 650 ident: CR56 article-title: REF, an evolutionary conserved family of hnRNP‐like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export publication-title: RNA contributor: fullname: Izaurralde – volume: 42 start-page: 903 year: 1985 end-page: 911 ident: CR39 article-title: The preferential translation of hsp70 mRNA requires sequences in the untranslated leader publication-title: Cell contributor: fullname: Lindquist – volume: 325 start-page: 1312 year: 2004 end-page: 1317 ident: CR18 article-title: Identification and functional analysis of consensus androgen response elements in human prostate cancer cells publication-title: Biochem Biophys Res Commun contributor: fullname: Inoue – volume: 10 start-page: 1608 year: 1996 end-page: 1620 ident: CR47 article-title: Regulation of mRNA export in response to stress in publication-title: Genes Dev contributor: fullname: Cole – volume: 17 start-page: 269 year: 2005 end-page: 273 ident: CR42 article-title: TREX, SR proteins and export of mRNA publication-title: Curr Opin Cell Biol contributor: fullname: Cheng – volume: 21 start-page: 160 year: 2007 end-page: 174 ident: CR62 article-title: The Spt6 SH2 domain binds Ser2‐P RNAPII to direct Iws1‐dependent mRNA splicing and export publication-title: Genes Dev contributor: fullname: Jones – volume: 22 start-page: 66 year: 2008 end-page: 78 ident: CR8 article-title: Definition of global and transcript‐specific mRNA export pathways in metazoans publication-title: Genes Dev contributor: fullname: Silver – volume: 26 start-page: 51 year: 2007 end-page: 62 ident: CR61 article-title: Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67‐Mtr2 publication-title: Mol Cell contributor: fullname: Hurt – volume: 18 start-page: 2593 year: 1999 end-page: 2609 ident: CR31 article-title: The Mex67p‐mediated nuclear mRNA export pathway is conserved from yeast to human publication-title: EMBO J contributor: fullname: Hurt – volume: 11 start-page: 558 year: 2004 end-page: 566 ident: CR44 article-title: Genome‐wide analysis of mRNAs regulated by the THO complex in publication-title: Nat Struct Mol Biol contributor: fullname: Izaurralde – volume: 17 start-page: 242 year: 2005 end-page: 250 article-title: Cotranscriptional mRNP assembly: from the DNA to the nuclear pore publication-title: Curr Opin Cell Biol – volume: 4 start-page: 2053 year: 1985 end-page: 2060 article-title: Selective translation of heat shock mRNA in depends on sequence information in the leader publication-title: EMBO J – volume: 7 start-page: 3509 year: 1988 end-page: 3518 article-title: Heat shock but not other stress inducers leads to the disruption of a sub‐set of snRNPs and inhibition of splicing in HeLa cells publication-title: EMBO J – volume: 8 start-page: 645 year: 2001 end-page: 656 article-title: Structural basis for the recognition of a nucleoporin FG repeat by the NTF2‐like domain of the TAP/p15 mRNA nuclear exprot factor publication-title: Mol Cell – volume: 2 start-page: 1361 year: 1993 end-page: 1368 article-title: Cloning of a novel, anonymous gene from a megabase‐range YAC and cosmid contig in the neurofibromatosis type 2/meningioma region on human chromosome 22q12 publication-title: Hum Mol Genet – volume: 101 start-page: 1858 year: 2004 end-page: 1862 article-title: Cotranscriptional recruitment of the serine‐arginine‐rich (SR)‐like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex publication-title: Proc Natl Acad Sci USA – volume: 11 start-page: 837 year: 2003 end-page: 843 article-title: SR splicing factors serve as adapter proteins for TAP‐dependent mRNA export publication-title: Mol Cell – volume: 282 start-page: 15645 year: 2007 end-page: 15651 article-title: The interaction between cap‐binding complex and RNA export factor is required for intronless mRNA export publication-title: J Biol Chem – volume: 159 start-page: 579 year: 2002 end-page: 588 article-title: REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export publication-title: J Cell Biol – volume: 150 start-page: 695 year: 2000 end-page: 706 article-title: Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export publication-title: J Cell Biol – volume: 9 start-page: 881 year: 2003 end-page: 891 article-title: The Ref/Aly proteins are dispensable for mRNA export and development in publication-title: RNA – volume: 11 start-page: 1716 year: 2001 end-page: 1721 article-title: The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in publication-title: Curr Biol – volume: 6 start-page: 638 year: 2000 end-page: 650 article-title: REF, an evolutionary conserved family of hnRNP‐like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export publication-title: RNA – volume: 417 start-page: 304 year: 2002 end-page: 308 article-title: TREX is a conserved complex coupling transcription with messenger RNA export publication-title: Nature – volume: 127 start-page: 1389 year: 2006 end-page: 1400 article-title: Human mRNA export machinery recruited to the 5′ end of mRNA publication-title: Cell – volume: 18 start-page: 2593 year: 1999 end-page: 2609 article-title: The Mex67p‐mediated nuclear mRNA export pathway is conserved from yeast to human publication-title: EMBO J – volume: 413 start-page: 648 year: 2001 end-page: 652 article-title: Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p publication-title: Nature – volume: 17 start-page: 269 year: 2005 end-page: 273 article-title: TREX, SR proteins and export of mRNA publication-title: Curr Opin Cell Biol – volume: 11 start-page: 558 year: 2004 end-page: 566 article-title: Genome‐wide analysis of mRNAs regulated by the THO complex in publication-title: Nat Struct Mol Biol – volume: 13 start-page: 201 year: 2004 end-page: 212 article-title: The Glc7p nuclear phosphatase promotes mRNA export by facilitating association of Mex67p with mRNA publication-title: Mol Cell – volume: 42 start-page: 903 year: 1985 end-page: 911 article-title: The preferential translation of hsp70 mRNA requires sequences in the untranslated leader publication-title: Cell – volume: 10 start-page: 1783 year: 2004 end-page: 1797 article-title: Internal ribosome entry site drives cap‐independent translation of reaper and heat shock protein 70 mRNAs in embryos publication-title: RNA – volume: 103 start-page: 2172 year: 2006 end-page: 2177 article-title: Simple fold composition and modular architecture of the nuclear pore complex publication-title: Proc Natl Acad Sci USA – volume: 19 start-page: 410 year: 2000 end-page: 420 article-title: Yra1p, a conserved nuclear RNA‐binding protein, interacts directly with Mex67p and is required for mRNA export publication-title: EMBO J – volume: 277 start-page: 9242 year: 2002 end-page: 9246 article-title: Complex formation between Tap and p15 affects binding to FG‐repeat nucleoporins and nucleocytoplasmic shuttling publication-title: J Biol Chem – volume: 1 start-page: 649 year: 1998 end-page: 659 article-title: TAP, the human homolog of Mex67p, mediates CTE‐dependent RNA export from the nucleus publication-title: Mol Cell – volume: 10 start-page: 1608 year: 1996 end-page: 1620 article-title: Regulation of mRNA export in response to stress in publication-title: Genes Dev – volume: 22 start-page: 66 year: 2008 end-page: 78 article-title: Definition of global and transcript‐specific mRNA export pathways in metazoans publication-title: Genes Dev – volume: 16 start-page: 3256 year: 1997 end-page: 3271 article-title: Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores publication-title: EMBO J – volume: 20 start-page: 8996 year: 2000 end-page: 9008 article-title: TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture publication-title: Mol Cell Biol – volume: 145 start-page: 1133 year: 1999 end-page: 1143 article-title: Intron‐independent association of splicing factors with active genes publication-title: J Cell Biol – volume: 21 start-page: 3526 year: 2002 end-page: 3535 article-title: The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability publication-title: EMBO J – volume: 23 start-page: 541 year: 1995 end-page: 549 article-title: 5′ Untranslated leader sequences of eukaryotic mRNAs encoding heat shock induced proteins publication-title: Nucl Acids Res – volume: 36 start-page: 616 year: 2007 end-page: 628 article-title: Nuclear RNA export factor 7 is localized in processing bodies and neuronal RNA granules through interactions with shuttling hnRNPs publication-title: Nucleic Acids Res – volume: 45 start-page: 185 year: 1986 end-page: 193 article-title: RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis publication-title: Cell – volume: 6 start-page: 136 year: 2000 end-page: 158 article-title: The C‐terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE‐bearing RNA substrates publication-title: RNA – volume: 27 start-page: 6 year: 2008 end-page: 16 article-title: A versatile interaction platform on the Mex67‐Mtr2 receptor creates an overlap between mRNA and ribosome export publication-title: EMBO J – volume: 19 start-page: 1512 year: 2005 end-page: 1517 article-title: Recruitment of the human TREX complex to mRNA during splicing publication-title: Genes Dev – volume: 45 start-page: 1585 year: 1997 end-page: 1592 article-title: Optimization of nuclear transcript detection by FISH and combination with fluorescence immunocytochemical detection of transcription factors publication-title: J Histochem Cytochem – volume: 22 start-page: 825 year: 1980 end-page: 834 article-title: Translational control of protein synthesis in response to heat shock in cells publication-title: Cell – volume: 13 start-page: 116 year: 2007 end-page: 128 article-title: Protein composition of human mRNPs spliced and differential requirements for mRNP protein recruitment publication-title: RNA – volume: 21 start-page: 1409 year: 2007 end-page: 1421 article-title: The RNA polymerase II CTD kinase Ctk1 functions in translation elongation publication-title: Genes Dev – volume: 28 start-page: 601 year: 2008 end-page: 608 article-title: ATP‐dependent recruitment of export factor Aly/REF onto intronless mRNAs by RNA helicase UAP56 publication-title: Mol Cell Biol – volume: 23 start-page: 2620 year: 2004 end-page: 2631 article-title: Biochemical analysis of TREX complex recruitment to intronless and intron‐containing yeast genes publication-title: EMBO J – volume: 21 start-page: 1288 year: 2007 end-page: 1291 article-title: Synchronicity: policing multiple aspects of gene expression by Ctk1 publication-title: Genes Dev – volume: 101 start-page: 9666 year: 2004 end-page: 9670 article-title: A molecular link between SR protein dephosphorylation and mRNA export publication-title: Proc Natl Acad Sci USA – volume: 8 start-page: 761 year: 2007 end-page: 773 article-title: Exporting RNA from the nucleus to the cytoplasm publication-title: Nat Rev Mol Cell Biol – volume: 407 start-page: 401 year: 2000 end-page: 405 article-title: The protein Aly links pre‐messenger‐RNA splicing to nuclear export in metazoans publication-title: Nature – volume: 98 start-page: 1030 year: 2001 end-page: 1035 article-title: REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus publication-title: Proc Natl Acad Sci USA – volume: 19 start-page: 5587 year: 2000 end-page: 5598 article-title: The structure of the mRNA export factor TAP reveals a arrangement of a non‐canonical RNP domain and an LRR domain publication-title: EMBO J – volume: 178 start-page: 1121 year: 2007 end-page: 1132 article-title: Nuclear mRNA export requires specific FG nucleoporins for translocation through the nuclear pore complex publication-title: J Cell Biol – volume: 325 start-page: 1312 year: 2004 end-page: 1317 article-title: Identification and functional analysis of consensus androgen response elements in human prostate cancer cells publication-title: Biochem Biophys Res Commun – volume: 21 start-page: 175 year: 2007 end-page: 183 article-title: IRES‐mediated functional coupling of transcription and translation amplifies insulin receptor feedback publication-title: Genes Dev – volume: 108 start-page: 523 year: 2002 end-page: 531 article-title: A conserved mRNA export machinery coupled to pre‐mRNA splicing publication-title: Cell – volume: 21 start-page: 160 year: 2007 end-page: 174 article-title: The Spt6 SH2 domain binds Ser2‐P RNAPII to direct Iws1‐dependent mRNA splicing and export publication-title: Genes Dev – volume: 26 start-page: 51 year: 2007 end-page: 62 article-title: Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67‐Mtr2 publication-title: Mol Cell – volume: 44 start-page: 429 year: 1986 end-page: 438 article-title: Translational and transcriptional control elements in the untranslated leader of the heat‐shock gene hsp22 publication-title: Cell – volume: 413 start-page: 644 year: 2001 end-page: 647 article-title: Pre‐mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly publication-title: Nature – volume: 265 start-page: 20377 year: 1990 end-page: 20383 article-title: Inactivation of splicing factors in HeLa cells subjected to heat shock publication-title: J Biol Chem – volume: 18 start-page: 6826 year: 1998 end-page: 6838 article-title: Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores publication-title: Mol Cell Biol – volume: 13 start-page: 1126 year: 1999 end-page: 1139 article-title: The human Tap protein is a nuclear mRNA export factor that contains novel RNA‐binding and nucleocytoplasmic transport sequences publication-title: Genes Dev – volume: 35 start-page: 3928 year: 2007 end-page: 3944 article-title: Proteomic analysis of ‐assembled pre‐mRNA splicing complexes expands the catalog of participating factors publication-title: Nucleic Acids Res – volume: 7 start-page: 1768 year: 2001 end-page: 1780 article-title: NXF1/p15 heterodimers are essential for mRNA nuclear export in publication-title: RNA – volume: 267 start-page: 21038 year: 1992 end-page: 21043 article-title: Preferential translation of heat shock mRNAs in HeLa cells deficient in protein synthesis initiation factors eIF‐4E and eIF‐4 gamma publication-title: J Biol Chem – ident: emboj20095-b55 doi: 10.1038/nature746 – ident: emboj20095-b45 doi: 10.1073/pnas.031586198 – ident: emboj20095-b12 doi: 10.1016/S1097-2765(04)00030-9 – ident: emboj20095-b31 doi: 10.1093/emboj/18.9.2593 – ident: emboj20095-b5 doi: 10.1093/nar/gkm347 – ident: emboj20095-b10 doi: 10.1083/jcb.200207128 – ident: emboj20095-b52 doi: 10.1083/jcb.150.4.695 – ident: emboj20095-b61 doi: 10.1016/j.molcel.2007.02.018 – ident: emboj20095-b43 doi: 10.1016/S0092-8674(02)00627-X – ident: emboj20095-b15 doi: 10.1261/rna.7154104 – ident: emboj20095-b2 doi: 10.1016/j.ceb.2005.03.001 – ident: emboj20095-b58 doi: 10.1083/jcb.200704174 – ident: emboj20095-b47 doi: 10.1101/gad.10.13.1608 – volume: 7 start-page: 3509 year: 1988 ident: emboj20095-b4 publication-title: EMBO J doi: 10.1002/j.1460-2075.1988.tb03227.x contributor: fullname: Bond U – ident: emboj20095-b20 doi: 10.1073/pnas.0403533101 – ident: emboj20095-b11 doi: 10.1016/S0960-9822(01)00532-2 – ident: emboj20095-b28 doi: 10.1101/gad.13.9.1126 – ident: emboj20095-b39 doi: 10.1016/0092-8674(85)90286-7 – ident: emboj20095-b25 doi: 10.1083/jcb.145.6.1133 – ident: emboj20095-b41 doi: 10.1074/jbc.M700629200 – volume: 265 start-page: 20377 year: 1990 ident: emboj20095-b50 publication-title: J Biol Chem doi: 10.1016/S0021-9258(17)30514-8 contributor: fullname: Shukla RR – ident: emboj20095-b19 doi: 10.1016/S1097-2765(03)00089-3 – ident: emboj20095-b38 doi: 10.1101/gad.1302205 – ident: emboj20095-b29 doi: 10.1093/nar/gkm556 – ident: emboj20095-b40 doi: 10.1261/rna.336807 – ident: emboj20095-b35 doi: 10.1261/rna.5420503 – ident: emboj20095-b53 doi: 10.1093/emboj/19.3.410 – ident: emboj20095-b9 doi: 10.1016/S1097-2765(01)00348-3 – ident: emboj20095-b14 doi: 10.1101/gad.1564807 – ident: emboj20095-b22 doi: 10.1073/pnas.0308663100 – volume: 18 start-page: 6826 year: 1998 ident: emboj20095-b48 publication-title: Mol Cell Biol doi: 10.1128/MCB.18.11.6826 contributor: fullname: Santos-Rosa H – ident: emboj20095-b54 doi: 10.1038/35098113 – ident: emboj20095-b46 doi: 10.1101/gad.428407 – ident: emboj20095-b49 doi: 10.1093/emboj/16.11.3256 – ident: emboj20095-b7 doi: 10.1073/pnas.0506345103 – ident: emboj20095-b51 doi: 10.1016/0092-8674(80)90559-0 – ident: emboj20095-b33 doi: 10.1038/nrm2255 – ident: emboj20095-b42 doi: 10.1016/j.ceb.2005.04.011 – ident: emboj20095-b1 doi: 10.1038/sj.emboj.7600261 – ident: emboj20095-b44 doi: 10.1038/nsmb759 – ident: emboj20095-b13 doi: 10.1016/S1097-2765(00)80065-9 – volume: 45 start-page: 1585 year: 1997 ident: emboj20095-b24 publication-title: J Histochem Cytochem doi: 10.1177/002215549704501201 contributor: fullname: Jolly C – ident: emboj20095-b26 doi: 10.1093/nar/23.4.541 – volume: 7 start-page: 1768 year: 2001 ident: emboj20095-b16 publication-title: RNA contributor: fullname: Herold A – ident: emboj20095-b17 doi: 10.1128/MCB.20.23.8996-9008.2000 – ident: emboj20095-b34 doi: 10.1093/emboj/19.21.5587 – ident: emboj20095-b36 doi: 10.1038/35098106 – ident: emboj20095-b64 doi: 10.1038/35030160 – ident: emboj20095-b59 doi: 10.1093/hmg/2.9.1361 – ident: emboj20095-b57 doi: 10.1128/MCB.01341-07 – ident: emboj20095-b30 doi: 10.1074/jbc.M110007200 – ident: emboj20095-b62 doi: 10.1101/gad.1503107 – ident: emboj20095-b60 doi: 10.1038/sj.emboj.7601947 – ident: emboj20095-b63 doi: 10.1016/0092-8674(86)90382-X – ident: emboj20095-b3 doi: 10.1017/S1355838200991994 – ident: emboj20095-b8 doi: 10.1101/gad.1616008 – volume: 267 start-page: 21038 year: 1992 ident: emboj20095-b27 publication-title: J Biol Chem doi: 10.1016/S0021-9258(19)36794-8 contributor: fullname: Joshi-Barve S – ident: emboj20095-b56 doi: 10.1017/S1355838200000078 – ident: emboj20095-b6 doi: 10.1016/j.cell.2006.10.044 – ident: emboj20095-b37 doi: 10.1101/gad.1506407 – volume: 4 start-page: 2053 year: 1985 ident: emboj20095-b32 publication-title: EMBO J doi: 10.1002/j.1460-2075.1985.tb03891.x contributor: fullname: Klemenz R – ident: emboj20095-b21 doi: 10.1016/0092-8674(86)90464-2 – ident: emboj20095-b23 doi: 10.1093/emboj/cdf335 – ident: emboj20095-b18 doi: 10.1016/j.bbrc.2004.10.174 |
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| Snippet | In metazoans, nuclear export of bulk mRNA is mediated by Tap‐p15, a conserved heterodimeric export receptor that cooperates with adaptor RNA‐binding proteins.... In metazoans, nuclear export of bulk mRNA is mediated by Tap-p15, a conserved heterodimeric export receptor that cooperates with adaptor RNA-binding proteins.... |
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| SubjectTerms | Active Transport, Cell Nucleus Amino Acid Sequence Binding sites Cell Line Cell Nucleus - metabolism EMBO36 heat shock mRNA HSP70 Heat-Shock Proteins - genetics HSP70 Heat-Shock Proteins - metabolism Humans Mammals Models, Molecular Molecular biology Molecular Sequence Data Nuclear Proteins - metabolism nucleo-cytoplasmic transport Nucleocytoplasmic Transport Proteins - physiology Proteins Ribonucleic acid RNA RNA, Messenger - metabolism RNA-Binding Proteins - metabolism RNA-Binding Proteins - physiology Transcription Factors - metabolism TREX complex |
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| Title | Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA |
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