Aquaporin water channels in transepithelial fluid transport

• Published in: The Journal of Medical Investigation Vol. 56; no. Supplement; pp. 179 - 184
• Main Authors: Tajima, Masato, Li, Lihua, Verkman, AS, Tradtrantip, Lukmanee
• Format: Journal Article
• Language: English
• Published: Japan The University of Tokushima Faculty of Medicine 2009
• Subjects: Animals; Aquaporins - genetics; Aquaporins - physiology; Biological Transport - physiology; Cell Membrane Permeability - physiology; Epithelial Cells - cytology; Epithelial Cells - physiology; epithelium; Exocrine Glands - cytology; Exocrine Glands - physiology; kidney; Kidney Tubules - cytology; Kidney Tubules - physiology; Mice; Mice, Knockout; Models, Animal; salivary gland; Water - metabolism; water channel; water transport

Aquaporins (AQPs) are membrane water channels that are involved in a diverse set of functions in mammalian physiology including epithelial fluid transport, brain water balance, cell migration, cell proliferation, neuroexcitation, fat metabolism, epidermal hydration, and others. Phenotype analysis of...