Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan
Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically r...
Saved in:
| Published in | Emerging infectious diseases Vol. 26; no. 12; pp. 3025 - 3029 |
|---|---|
| Main Authors | , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
U.S. National Center for Infectious Diseases
01.12.2020
Centers for Disease Control and Prevention |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor. |
|---|---|
| AbstractList | Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor. Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor. Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus’ spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus , but not humans, as an entry receptor. |
| Audience | Professional Academic |
| Author | Suzuki, Jin Takenaka-Uema, Akiko Shimojima, Masayuki Kamiki, Haruhiko Kitamura, Tomoya Matsugo, Hiromichi Ishida, Hiroho Horimoto, Taisuke Murakami, Shin Sato, Ryouta Fujii, Marina Aoi, Toshiki |
| Author_xml | – sequence: 1 givenname: Shin surname: Murakami fullname: Murakami, Shin – sequence: 2 givenname: Tomoya surname: Kitamura fullname: Kitamura, Tomoya – sequence: 3 givenname: Jin surname: Suzuki fullname: Suzuki, Jin – sequence: 4 givenname: Ryouta surname: Sato fullname: Sato, Ryouta – sequence: 5 givenname: Toshiki surname: Aoi fullname: Aoi, Toshiki – sequence: 6 givenname: Marina surname: Fujii fullname: Fujii, Marina – sequence: 7 givenname: Hiromichi surname: Matsugo fullname: Matsugo, Hiromichi – sequence: 8 givenname: Haruhiko surname: Kamiki fullname: Kamiki, Haruhiko – sequence: 9 givenname: Hiroho surname: Ishida fullname: Ishida, Hiroho – sequence: 10 givenname: Akiko surname: Takenaka-Uema fullname: Takenaka-Uema, Akiko – sequence: 11 givenname: Masayuki surname: Shimojima fullname: Shimojima, Masayuki – sequence: 12 givenname: Taisuke surname: Horimoto fullname: Horimoto, Taisuke |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33219796$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNk8uP0zAQxiO0iH3AlSOKhIRAIsWPxE4uSKW8Fq20qIW9mokzab1K48V2VpS_HrfdV9EioRxiTX7flxnPzGGy19sek-QpJSPOCH2DpmGCshEjnJfiQXJASUkyQYpq7-ack_3k0PtzQmiUVI-Sfc4ZrWQlDpIf7zGgDsb2KfRNOlmAAx3Qmd-wCdo2fQchnYGrUdtL4waffl2sOjvHHoPR0HWrdIodBGzSYNPZeDrLJvYsY6_TL3AB_ePkYQudxydX76Pk-8cP3yafs5PTT8eT8UmmBS1DVgOWea2lLLTQouB1LoELlC1tUdQNsoYXsc48r0lFGaOUlwwkcg4FZ5JW_Cg53vo2Fs7VhTNLcCtlwahNwLq5AhcT7lA1hIiyaQGJrPJ4rAsBdVVWNZVaF6SIXm-3XhdDvcRGYx8cdDumu196s1Bze6mkJKISa4OXVwbO_hzQB7U0XmPXQY928IrlglOSs3Kd9_O_0HM7uD5eVaSkYKIseH5LzSEWYPrWxv_qtakai7yoCiqIjFR2D7XuVEwyzk1rYniHH93Dx6fBpdH3Cl7tCCIT8FeYw-C9Op5N_589PdtlX9xhFwhdWHjbDesR9Lvgs7uduWnJ9UBHIN8C2lnvHbZKm7AZ5Via6RQlar036mpv1HZvbm_iRnbt_A_BH45pExc |
| CitedBy_id | crossref_primary_10_17352_2455_5363_000054 crossref_primary_10_1016_j_cell_2021_06_008 crossref_primary_10_1093_ve_veac046 crossref_primary_10_3892_br_2022_1540 crossref_primary_10_1038_s41598_023_35861_7 crossref_primary_10_1186_s40168_024_01955_1 crossref_primary_10_3390_v15051187 crossref_primary_10_1186_s12915_024_02074_x crossref_primary_10_1515_mr_2021_0035 crossref_primary_10_1016_j_virol_2022_09_002 crossref_primary_10_1016_j_ijid_2023_02_015 crossref_primary_10_3390_pathogens12060775 crossref_primary_10_1111_mec_17645 crossref_primary_10_1097_ID9_0000000000000008 crossref_primary_10_1038_s41467_024_53029_3 crossref_primary_10_1111_tbed_14356 crossref_primary_10_1186_s12862_022_02078_7 crossref_primary_10_1016_j_banm_2021_05_008 crossref_primary_10_1016_S0140_6736_21_02020_1 crossref_primary_10_1128_jvi_00961_22 crossref_primary_10_1038_s41421_023_00581_9 crossref_primary_10_3390_v13061073 crossref_primary_10_1093_nsr_nwac213 crossref_primary_10_1038_s42003_023_05436_3 crossref_primary_10_1128_jvi_00608_22 crossref_primary_10_1016_j_micpath_2025_107328 crossref_primary_10_3390_v13112188 crossref_primary_10_1128_mbio_02566_22 crossref_primary_10_1080_22221751_2021_1964925 crossref_primary_10_1111_cobi_14157 crossref_primary_10_1080_22221751_2021_1898291 crossref_primary_10_1128_spectrum_02591_23 crossref_primary_10_1093_oxfimm_iqac003 crossref_primary_10_1093_gbe_evac161 crossref_primary_10_1126_sciadv_adr8772 crossref_primary_10_1080_22221751_2022_2151383 crossref_primary_10_1146_annurev_virology_100120_015057 crossref_primary_10_3390_microorganisms11040959 crossref_primary_10_1080_22221751_2021_1956373 crossref_primary_10_1128_jvi_00990_23 crossref_primary_10_1016_j_heha_2022_100006 crossref_primary_10_1128_jvi_00395_23 crossref_primary_10_1111_tbed_14695 crossref_primary_10_1038_s41598_024_71791_8 crossref_primary_10_1073_pnas_2215067120 crossref_primary_10_1007_s11356_021_12553_1 crossref_primary_10_3389_fpubh_2022_826116 crossref_primary_10_1016_j_ebiom_2022_103990 crossref_primary_10_1128_jvi_01002_22 crossref_primary_10_1016_j_gene_2022_146641 crossref_primary_10_1111_xen_12685 crossref_primary_10_1038_s41564_024_01765_z crossref_primary_10_1620_tjem_2022_J093 crossref_primary_10_7717_peerj_12681 crossref_primary_10_1016_j_ebiom_2024_105181 crossref_primary_10_1038_s41586_021_04188_6 crossref_primary_10_1038_s41467_021_21240_1 crossref_primary_10_1273_cbij_22_1 crossref_primary_10_1038_s41598_021_94011_z crossref_primary_10_1016_j_jobb_2021_06_002 crossref_primary_10_1016_j_coviro_2021_12_008 crossref_primary_10_3390_v14091914 crossref_primary_10_1038_s41467_022_31860_w crossref_primary_10_1128_JVI_00083_21 crossref_primary_10_1093_ve_veae020 crossref_primary_10_1371_journal_pone_0279221 crossref_primary_10_15252_embr_202256055 crossref_primary_10_3390_v14081809 crossref_primary_10_1016_j_coviro_2021_04_013 crossref_primary_10_1016_j_xinn_2021_100159 crossref_primary_10_1038_s41586_022_04532_4 crossref_primary_10_3390_v14010113 crossref_primary_10_1371_journal_ppat_1012704 crossref_primary_10_46234_ccdcw2021_210 crossref_primary_10_1038_d41586_020_03217_0 crossref_primary_10_1038_s43016_021_00285_x crossref_primary_10_1007_s00705_021_05357_8 crossref_primary_10_1038_s41586_022_04464_z crossref_primary_10_3390_pathogens11080877 crossref_primary_10_1557_s43577_021_00167_4 crossref_primary_10_1016_j_isci_2023_108080 crossref_primary_10_1038_s41597_023_02558_5 crossref_primary_10_1016_j_celrep_2022_111831 crossref_primary_10_3390_v13081510 crossref_primary_10_1016_j_micinf_2024_105425 crossref_primary_10_1055_s_0042_1759889 crossref_primary_10_1016_j_cell_2023_08_029 crossref_primary_10_1111_xen_12671 crossref_primary_10_1093_molbev_msab327 crossref_primary_10_3390_ijerph20043702 crossref_primary_10_1128_jvi_01719_22 crossref_primary_10_3390_v14020440 crossref_primary_10_1016_j_virol_2025_110426 crossref_primary_10_1038_s41467_024_49693_0 crossref_primary_10_1128_mbio_01404_24 crossref_primary_10_3201_eid2812_220801 crossref_primary_10_36233__0507_4088_233 crossref_primary_10_1038_s41586_023_06043_2 crossref_primary_10_3390_v15091897 |
| Cites_doi | 10.1292/jvms.14-0012 10.1038/s41586-020-2012-7 10.3390/v12060629 10.1126/science.1087139 10.1128/JVI.00650-10 10.1038/s41564-020-0688-y 10.1016/j.ympev.2009.09.021 10.1371/journal.ppat.1006698 10.1128/MRA.00548-19 10.1038/nature12711 10.1128/JVI.02582-15 10.1128/JVI.02232-10 10.1038/s41586-020-2180-5 10.1016/j.cub.2020.03.022 10.3201/eid2607.200092 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2020 U.S. National Center for Infectious Diseases Published 2020. This article is a U.S. Government work and is in the public domain in the USA. |
| Copyright_xml | – notice: COPYRIGHT 2020 U.S. National Center for Infectious Diseases – notice: Published 2020. This article is a U.S. Government work and is in the public domain in the USA. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM IOV ISR 3V. 7RV 7X7 7XB 8C1 8FI 8FJ 8FK ABUWG AEUYN AFKRA AZQEC BENPR CCPQU FYUFA GHDGH K9- K9. KB0 M0R M0S NAPCQ PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS 7X8 5PM DOA |
| DOI | 10.3201/eid2612.203386 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Gale In Context: Opposing Viewpoints Gale In Context: Science ProQuest Central (Corporate) Nursing & Allied Health Database ProQuest Health & Medical Collection ProQuest Central (purchase pre-March 2016) Public Health Database Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest One Sustainability ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One Community College Health Research Premium Collection Health Research Premium Collection (Alumni) Consumer Health Database (Alumni Edition) ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) Consumer Health Database ProQuest Health & Medical Collection ProQuest Nursing and Allied Health Premium ProQuest Central Premium ProQuest One Academic ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Family Health (Alumni Edition) ProQuest Central China ProQuest Central ProQuest One Sustainability Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Health & Medical Research Collection ProQuest Central (New) ProQuest Public Health ProQuest Family Health ProQuest One Academic Eastern Edition ProQuest Nursing & Allied Health Source ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest One Academic UKI Edition ProQuest Nursing & Allied Health Source (Alumni) ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE ProQuest One Academic Middle East (New) |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Public Health |
| DocumentTitleAlternate | Bat Sarbecovirus Related to SARS-CoV-2, Japan |
| EISSN | 1080-6059 |
| EndPage | 3029 |
| ExternalDocumentID | oai_doaj_org_article_d0068dfae0794068b56ab989b17cc505 PMC7706965 A645951607 33219796 10_3201_eid2612_203386 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GeographicLocations | Japan Asia |
| GeographicLocations_xml | – name: Japan – name: Asia |
| GroupedDBID | --- -~X .GJ 186 29G 2WC 36B 53G 5GY 5VS 6PF 7RV 7X7 85S 8C1 8FI 8FJ 9K5 A8Z AAWTL AAYOK AAYXX ABDBF ABUWG ACGFO ACUHS ADBBV ADRAZ AEGXH AENEX AETEA AEUYN AFKRA AIAGR ALIPV ALMA_UNASSIGNED_HOLDINGS AOIJS AZQEC B0M BAWUL BCNDV BENPR C1A CCPQU CITATION DIK DO4 E3Z EAD EAP EAS EBC EBD EBS EDH EJD EMB EMH EMI EMK EMOBN EPL EPT ESX F5P FRP FYUFA GROUPED_DOAJ GX1 HMCUK HYE IAO IBB IEA IEP IHR IHW IMI INH INR IOF IOV IPO ISR ITC K9- KQ8 M0R M48 NAPCQ NEJ O5R O5S OK1 OVT P2P PGMZT PHGZM PHGZT PV9 Q.E QF4 QM9 QN7 QO4 Q~Q RGD RGQ RNS RPM RXW RZL SV3 TAE TR2 TUS TWZ UKHRP UQL W2D WH7 WOQ WOW XJT XSB YRT YV5 YXF ZBA ZGI ~8M 0ZS ACZ CGR CUY CVF ECM EIF M~E NPM PMFND 3V. 7XB 8FK K9. PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS 7X8 5PM PUEGO |
| ID | FETCH-LOGICAL-c618t-bae84bc775c6c653b47a36e7f1fe6bde2d3561244b0912211382a7e33a5327193 |
| IEDL.DBID | M48 |
| ISSN | 1080-6040 1080-6059 |
| IngestDate | Wed Aug 27 01:29:21 EDT 2025 Sun Aug 31 08:11:28 EDT 2025 Fri Jul 11 15:06:37 EDT 2025 Sat Jul 26 03:29:47 EDT 2025 Tue Jun 17 21:44:48 EDT 2025 Thu Jun 12 23:28:38 EDT 2025 Tue Jun 10 20:35:41 EDT 2025 Fri Jun 27 05:12:54 EDT 2025 Fri Jun 27 05:03:33 EDT 2025 Thu May 22 21:06:37 EDT 2025 Wed Feb 19 02:29:45 EST 2025 Thu Apr 24 22:58:11 EDT 2025 Tue Jul 01 03:30:00 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 12 |
| Keywords | viruses bat sarbecovirus Japan betacoronavirus SARS coronavirus zoonoses respiratory infections COVID-19 SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Rhinolophus cornutus coronavirus disease |
| Language | English |
| License | This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c618t-bae84bc775c6c653b47a36e7f1fe6bde2d3561244b0912211382a7e33a5327193 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| OpenAccessLink | http://journals.scholarsportal.info/openUrl.xqy?doi=10.3201/eid2612.203386 |
| PMID | 33219796 |
| PQID | 2476268534 |
| PQPubID | 105375 |
| PageCount | 5 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_d0068dfae0794068b56ab989b17cc505 pubmedcentral_primary_oai_pubmedcentral_nih_gov_7706965 proquest_miscellaneous_2463104289 proquest_journals_2476268534 gale_infotracmisc_A645951607 gale_infotracgeneralonefile_A645951607 gale_infotracacademiconefile_A645951607 gale_incontextgauss_ISR_A645951607 gale_incontextgauss_IOV_A645951607 gale_healthsolutions_A645951607 pubmed_primary_33219796 crossref_citationtrail_10_3201_eid2612_203386 crossref_primary_10_3201_eid2612_203386 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2020-12-00 20201201 2020-12-01 |
| PublicationDateYYYYMMDD | 2020-12-01 |
| PublicationDate_xml | – month: 12 year: 2020 text: 2020-12-00 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: Atlanta |
| PublicationTitle | Emerging infectious diseases |
| PublicationTitleAlternate | Emerg Infect Dis |
| PublicationYear | 2020 |
| Publisher | U.S. National Center for Infectious Diseases Centers for Disease Control and Prevention |
| Publisher_xml | – name: U.S. National Center for Infectious Diseases – name: Centers for Disease Control and Prevention |
| References | Stoffberg (key-10.3201/eid2612.203386-202011181238-R12) 2010; 54 Glowacka (key-10.3201/eid2612.203386-202011181238-R7) 2011; 85 Hu (key-10.3201/eid2612.203386-202011181238-R2) 2017; 13 key-10.3201/eid2612.203386-202011181238-R3 Letko (key-10.3201/eid2612.203386-202011181238-R5) 2020; 5 Lau (key-10.3201/eid2612.203386-202011181238-R10) 2020; 26 Zhou (key-10.3201/eid2612.203386-202011181238-R9) 2020; 579 Zhang (key-10.3201/eid2612.203386-202011181238-R11) 2020; 30 Lan (key-10.3201/eid2612.203386-202011181238-R6) 2020; 581 Suzuki (key-10.3201/eid2612.203386-202011181238-R4) 2014; 76 Ge (key-10.3201/eid2612.203386-202011181238-R13) 2013; 503 Drexler (key-10.3201/eid2612.203386-202011181238-R1) 2010; 84 Yamamoto (key-10.3201/eid2612.203386-202011181238-R8) 2020; 12 Guan (key-10.3201/eid2612.203386-202011181238-R15) 2003; 302 Yang (key-10.3201/eid2612.203386-202011181238-R14) 2015; 90 |
| References_xml | – volume: 76 start-page: 1267 year: 2014 ident: key-10.3201/eid2612.203386-202011181238-R4 article-title: Group B betacoronavirus in rhinolophid bats, Japan. publication-title: J Vet Med Sci doi: 10.1292/jvms.14-0012 – volume: 579 start-page: 270 year: 2020 ident: key-10.3201/eid2612.203386-202011181238-R9 article-title: A pneumonia outbreak associated with a new coronavirus of probable bat origin. publication-title: Nature doi: 10.1038/s41586-020-2012-7 – volume: 12 start-page: E629 year: 2020 ident: key-10.3201/eid2612.203386-202011181238-R8 article-title: The anticoagulant nafamostat potently inhibits SARS-CoV-2 S protein-mediated fusion in a cell fusion assay system and viral infection in vitro in a cell-type-dependent manner. publication-title: Viruses doi: 10.3390/v12060629 – volume: 302 start-page: 276 year: 2003 ident: key-10.3201/eid2612.203386-202011181238-R15 article-title: Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. publication-title: Science doi: 10.1126/science.1087139 – volume: 84 start-page: 11336 year: 2010 ident: key-10.3201/eid2612.203386-202011181238-R1 article-title: Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequences. publication-title: J Virol doi: 10.1128/JVI.00650-10 – volume: 5 start-page: 562 year: 2020 ident: key-10.3201/eid2612.203386-202011181238-R5 article-title: Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. publication-title: Nat Microbiol doi: 10.1038/s41564-020-0688-y – volume: 54 start-page: 1 year: 2010 ident: key-10.3201/eid2612.203386-202011181238-R12 article-title: Molecular phylogenetics and historical biogeography of Rhinolophus bats. publication-title: Mol Phylogenet Evol doi: 10.1016/j.ympev.2009.09.021 – volume: 13 start-page: e1006698 year: 2017 ident: key-10.3201/eid2612.203386-202011181238-R2 article-title: Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus. publication-title: PLoS Pathog doi: 10.1371/journal.ppat.1006698 – ident: key-10.3201/eid2612.203386-202011181238-R3 doi: 10.1128/MRA.00548-19 – volume: 503 start-page: 535 year: 2013 ident: key-10.3201/eid2612.203386-202011181238-R13 article-title: Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor. publication-title: Nature doi: 10.1038/nature12711 – volume: 90 start-page: 3253 year: 2015 ident: key-10.3201/eid2612.203386-202011181238-R14 article-title: Isolation and characterization of a novel bat coronavirus closely related to the direct progenitor of severe acute respiratory syndrome coronavirus. publication-title: J Virol doi: 10.1128/JVI.02582-15 – volume: 85 start-page: 4122 year: 2011 ident: key-10.3201/eid2612.203386-202011181238-R7 article-title: Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response. publication-title: J Virol doi: 10.1128/JVI.02232-10 – volume: 581 start-page: 215 year: 2020 ident: key-10.3201/eid2612.203386-202011181238-R6 article-title: Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor. publication-title: Nature doi: 10.1038/s41586-020-2180-5 – volume: 30 start-page: 1346 year: 2020 ident: key-10.3201/eid2612.203386-202011181238-R11 article-title: Probable pangolin origin of SARS-CoV-2 associated with the COVID-19 outbreak. publication-title: Curr Biol doi: 10.1016/j.cub.2020.03.022 – volume: 26 start-page: 1542 year: 2020 ident: key-10.3201/eid2612.203386-202011181238-R10 article-title: Possible bat origin of severe acute respiratory syndrome coronavirus 2. publication-title: Emerg Infect Dis doi: 10.3201/eid2607.200092 |
| SSID | ssj0012019 |
| Score | 2.6080616 |
| Snippet | Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to... Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to... |
| SourceID | doaj pubmedcentral proquest gale pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 3025 |
| SubjectTerms | Angiotensin-Converting Enzyme 2 - metabolism Animals Animals as carriers of disease bat sarbecovirus Bats Bats as carriers of disease betacoronavirus Betacoronavirus - genetics Betacoronavirus - physiology Chiroptera - virology Coronavirus Infections - epidemiology Coronavirus Infections - veterinary Coronavirus Infections - virology Coronaviruses COVID-19 Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan Dispatch Distribution Epidemiology Health aspects HEK293 Cells Humans Identification and classification Japan - epidemiology Phylogeny respiratory infections Rhinolophus cornutus SARS-CoV-2 SARS-CoV-2 - genetics SARS-CoV-2 - physiology Severe acute respiratory syndrome coronavirus 2 Spike Glycoprotein, Coronavirus - genetics Spike Glycoprotein, Coronavirus - metabolism Virus Internalization Viruses |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELZQT0gI8SalgEGIXoi6Gzt2fNxuW5VKPNSlVW_Gjp12pSpBu1kk_j0zcTZaq1Rw4JbEX6RoZuyZcWY-E_KOMVc46SA7yfE3I7j01OKtLUVpK8W46Db0P30Wx2f85CK_2DjqC2vCAj1wENyewyYGVxk_AsuBS5sLY1Wh7FiWZR7YS8HnrZOp_v8BuDUVSushOQI7DXSNDB7v-blD2ixIDSE7E5E76lj7b67NG84pLpzc8ERHD8j9PoSkk_DpD8kdXz8i98L-Gw1tRY_J9wPfdlVWNTW1o9OBlzm0XdKmovumpTOzAPE2P-eL1ZJ-vYLsHQwq9DVe_6JdpZx3tG3obHI6S6fNeZp9oCfgYOsn5Ozo8Nv0OO1PU0hLMS7a1BpfcFtKmYMaRM4sl4YJL6tx5YV1PnMMT8rk3II4M8gLWZEZ6RkzOcskxHlPyVbd1P45lkPB-joy3FWZ4UXGjLKmyBVgOVfFyCQkXQtVlz3VOJ54ca0h5UAl6F4JOighIbsD_kcg2bgVuY86GlBIjt09AJPRvcnov5lMQl6jhnXoNB2muJ4gsU6OjHsJedshkCCjxgqcS7NaLvXHL-f_AJqdRqDdHlQ1IILS9F0PIEgk3oqQ7yPkZaAd_xNwJwLCelDGw2vD1f16tNQZB6cnIDTjCXkzDOObWGNX-2aFGAGxPqSjKiHPgp0PcmYMPJtUIH8ZzYBIEfFIPb_q2MqlHAkl8u3_obkX5G6G-x1dOdEO2WoXK_8SgsLWvurm_28pzljK priority: 102 providerName: Directory of Open Access Journals – databaseName: ProQuest Health & Medical Collection dbid: 7X7 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1bb9MwFLZgvCAhxJ2wAQYh9kK0Nnbs5Al1hWlM4qKVTX0zdux0laZka1Ik_j3nxG5YxEW8tfFXqTrH5-ac85mQV4zZzEoL1UmKrxkhpMcGv5pCFKbMGRfdgf7HT-LwhB_N03k4cGtCW-XGJ3aO2tYFnpHvJRzMVkBw4W8vLmO8NQrfroYrNK6TG0hdhrtazvuCawzBLfcN9lAiwW71pI0MHu-5pUXyLCgQoUYTg6DUcff_7qGvhKhh--SVeHRwh9wOiSSdeM3fJddcdY_c8qdw1A8X3Sff3rm267WqqK4snfbszH74ktYl3dctnekVCLn-vlytG_rlDGp42FZ-uvH8B-365ZylbU1nk-NZPK1P4-QNPYIwWz0gJwfvv04P43CnQlyIcdbGRruMm0LKFJQhUma41Ew4WY5LJ4x1iWV4XybnBhKJBKpDliVaOsZ0yhIJ2d5DslXVlXuMTVHgZUea2zLRPEuYzo3O0hywnOfZSEck3ghVFYFwHO-9OFdQeKASVFCC8kqIyG6Pv_BUG39F7qOOehRSZHcP6tVCBYtTFqdfbKndCFwOfDSp0CbPcjOWRQF5X0Seo4aVnzftDV1NkF4nRd69iLzsEEiTUWEfzkKvm0Z9-Hz6H6DZ8QC0G0BlDSIodJh9AEEi_dYA-XqAXHjy8T8BdwZA8ArFcHmzcVXwSo36ZUMRedEv4y-x065y9RoxAjJ-KErziDzy-7yXM2MQ32QO8pcDCxgoYrhSLc86znIpRyIX6ZN__61tcjPB84yuXWiHbLWrtXsKSV9rnnWW_RNf4lCU priority: 102 providerName: ProQuest |
| Title | Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/33219796 https://www.proquest.com/docview/2476268534 https://www.proquest.com/docview/2463104289 https://pubmed.ncbi.nlm.nih.gov/PMC7706965 https://doaj.org/article/d0068dfae0794068b56ab989b17cc505 |
| Volume | 26 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3fb9MwELbY9oKEEL8JjGIQYi8E2tixkweE2m7VmLQxtXTqW7ATp6tUJZCmiP333MVptogi7aVp4y8PvbN9d87dd4S8YywJEplAdOLja0Yw6a7GnzoWsU5DxkV1oH96Jo6n_GTmz67zn2oBrraGdthPalosP_75dfUFFvxnjDjBfn0yiwSJsCDYg3hL7JA9sEoSuxmc8us3CgAMbbI9hEswcy2B45bnWwaq4vH_d7e-Ya7aqZQ3bNPoAblfO5W0b2fBQ3LHZI_IPXsiR22h0WPy49CUVd5VRlWW0GHD1GwLMWme0oEq6UQVIPD896JYr-j5JcTzMMVspePyila5cyahZU4n_fHEHeYXrveBnoDJzZ6Q6ejo-_DYrfsruLHoBaWrlQm4jqX0QTHCZ5pLxYSRaS81QifGSxj2zuRcg1PhQaTIAk9Jw5jymSfB83tKdrM8M88xQQp23K7iSeopHnhMhVoFfghYzsOgqxziboQaxTX5OPbAWEYQhKASoloJkVWCQw4a_E9Lu_Ff5AB11KCQLru6kRfzqF59UYKVMEmqTBe2H_iqfaF0GIS6J-MYfECHvEYNR7b2tFn0UR-pdnzk4HPI2wqBlBkZ5uTM1Xq1ir5-u7gFaDJugQ5qUJqDCGJV10GAIJGKq4V830LOLRH5NuB-Cwg7RNwe3kzcaLPAIo-DGRTgrHGHvGmG8UnMustMvkaMAO8fAtTQIc_sPG_kzBjYOhmC_GVrBbQU0R7JFpcVf7mUXREK_8Vt_95LctfDKjJMIuL7ZLcs1uYVuIKl7pAdOZPwGQx7HbLXHxwORnAdHJ2djzvV8Uqn2gX-An5oXNM |
| linkProvider | Scholars Portal |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwELem8QASQnwvMJhBwF6I1saOnTwg1HVM675A6zbtzbMTp6s0JaNNQf2n-Bu5i9OwiA_xsrcm_lWK7nx3Oefud4S8YSyNUplCdhLiZ0YI6b7BS5OIxGQx46I60D84FDsnfPcsPFsiPxa9MFhWufCJlaNOiwTPyDcCDmYrILjwj1dffZwahV9XFyM03LbYs_PvkLJNPwy2QL9vg2D703F_x6-nCviJ6Ealb7SNuEmkDOFxRMgMl5oJK7NuZoVJbZAynBjJuYFQGkB-xKJAS8uYDlkgu0i-BC7_FmdgmtiZ3m9KSroQTGNX0A8pGViHI4lkcHvDjlMk64KEFHJC0QqC1ayA3yPCtZDYLte8Fv-275N79Ysr7bmd9oAs2fwhuetO_ahrZnpEzrdsWdV25VTnKe03bNCu2ZMWGd3UJR3qCSi1-DaezKb0y8Uc_C-43OpU_XJOq_o8m9KyoMPe0dDvF6d-8J7uQljPH5OTG5H2E7KcF7ldwSIs8OodzdMs0DwKmI6NjsIYsJzHUUd7xF8IVSU1wTnO2bhUkOigElStBOWU4JH1Bn_lqD3-itxEHTUopOSubhSTkaotXKXYbZNm2nbAxcFPEwpt4ig2XZkk8J7pkTXUsHL9rY1jUT2k8wmR588jrysE0nLkWPcz0rPpVA0-n_4HaHjUAq3XoKwAESS67rUAQSLdVwv5roUcObLzPwFXW0DwQkl7ebFxVe0Fp-qXzXrkVbOM_8TKvtwWM8QIyDAgCY498tTt80bOjEE8lTHIX7YsoKWI9ko-vqg40qXsiFiEz_79WGvk9s7xwb7aHxzuPSd3AjxLqUqVVslyOZnZF_DCWZqXlZVTcn7TbuUn4a-L1Q |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwELemISEkhPheYDCDgL0QtY0TO3lAqGup1g3GtLJpb54dO12lKRn9APVf46_jLk7DIj7Ey96a-FcpuvPd5Zy73xHyijETG2EgO4nwMyOEdF_jpU55qrOEhbw80P90wHePw73T6HSN_Fj1wmBZ5conlo7aFCmekbeCEMyWQ3AJW1lVFnHYH7y__OrjBCn80roap-G2yL5dfof0bfZu2Addvw6CwYcvvV2_mjDgp7wTz32tbBzqVIgIHo1HTIdCMW5F1sks18YGhuH0yDDUEFYDyJVYHChhGVMRC0QHiZjA_d8QTMRoY3GvLi_pQGBNXHE_pGdgKY4wksHtlp0YJO6C5BTyQ94IiOXcgN-jw5Xw2CzdvBILB3fJneollnbdrrtH1mx-n9x2J4DUNTY9IGd9Oy_rvHKqckN7NTO0a_ykRUZ31JyO1BQUXHybTBczeni-BF8M7rc8Yb9Y0rJWzxo6L-ioezTye8WJH7ylexDi84fk-Fqk_Yis50VuN7AgCzx8W4UmC1QYB0wlWsVRAtgwTOK28oi_EqpMK7JznLlxISHpQSXISgnSKcEj2zX-0tF8_BW5gzqqUUjPXd4opmNZWbs02HljMmXb4O7gp4640kmc6I5IU3jn9MgWali6XtfaycguUvtEyPnnkZclAik6ctzsY7WYzeTw88l_gEZHDdB2BcoKEEGqqr4LECRSfzWQbxrIsSM-_xNwswEEj5Q2l1cbV1YecSZ_2a9HXtTL-E-s8sttsUAMh2wDEuLEI4_dPq_lzBjEVpGA_EXDAhqKaK7kk_OSL12INk949OTfj7VFboJDkR-HB_tPya0Aj1XKqqVNsj6fLuwzePec6-elkVNydt1e5SfWY5AL |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Detection+and+Characterization+of+Bat+Sarbecovirus+Phylogenetically+Related+to+SARS-CoV-2%2C+Japan&rft.jtitle=Emerging+infectious+diseases&rft.au=Murakami%2C+Shin&rft.au=Kitamura%2C+Tomoya&rft.au=Suzuki%2C+Jin&rft.au=Sato%2C+Ryouta&rft.date=2020-12-01&rft.pub=U.S.+National+Center+for+Infectious+Diseases&rft.issn=1080-6040&rft.volume=26&rft.issue=12&rft.spage=3025&rft_id=info:doi/10.3201%2Feid2612.203386&rft.externalDocID=A645951607 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1080-6040&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1080-6040&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1080-6040&client=summon |