Genomic evidence for low genetic diversity but purging of strong deleterious variants in snow leopards - Yang, Lin; Jin, Hong; Yang, Qien; Poyarkov, Andrey; Korablev, Miroslav; Rozhnov, Viatcheslav; Shao, Junjie; Fu, Qiaomei; Hernandez-Blanco, Jose Antonio; Zhan, Xiangjiang; Yu, Li; Alexandrov, Dmitry; et al. (Genome Biology, 2025)
Keywords: Amino acids; Animals; Asia; Biogeography; Climate change; Conserved sequence; Deleterious variants; Demography; EPAS1; Evolution; Evolution, Molecular; Gene Frequency; Genetic diversity; Genetic load; Genetic structure; Genetic Variation; Genome; Genomes; Genomic diversity; Genomics; Himalayan region; History; Inbreeding; metagenomics; Microclimate; Mountains; Nucleotide sequence; Panthera - genetics; Panthera uncia; Phylogenetics; Phylogeny; Population; Population decline; population dynamics; Population genetics; Population genomics; Predation; Selection, Genetic; snow; Snow leopards; species; Survival; Taxonomy; Threatened species; viability; Tibetan Plateau; Tien Shan Mountains; Mongolia; Himalaya Mountains; China; Tajikistan; Russia; Himalayan region; Asia; EPAS1; Genetic structure; Genomic diversity; Snow leopards; Deleterious variants; Population genomics