Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance - Sun, Fei; Ding, Yue; Ji, Quanjiang; Liang, Zhongjie; Deng, Xin; Wong, Catherine C. L; Yi, Chengqi; Zhang, Liang; Xie, Sherrie; Alvarez, Sophie; Hicks, Leslie M; Luo, Cheng; et al. (Proceedings of the National Academy of Sciences - PNAS, 2012)
Keywords: Abscess - microbiology; Amino Acid Sequence; Amino acids; animal models; Animals; Antibiotic resistance; Antibiotics; Bacteria; Bacterial Proteins - chemistry; Biological Sciences; ceftriaxone; Cell extracts; Cells; cysteine; Cysteine - chemistry; Drug resistance; Drug Resistance, Microbial; Gene Expression Regulation, Bacterial; Mice; Molecular Sequence Data; Phosphatases; Phosphorylation; Physical Sciences; Physiological regulation; post-translational modification; Protein Binding; Protein Kinase C - metabolism; Protein Processing, Post-Translational; Protein-Serine-Threonine Kinases - metabolism; Proteins; Rodents; Sequence Homology, Amino Acid; Signal transduction; Staphylococcus aureus; Staphylococcus aureus - metabolism; Trans-Activators - chemistry; transcription factors; Transcription Factors - chemistry; vancomycin; Vancomycin - pharmacology; Virulence; Virulence Factors - metabolism; Yeast