Estimating the Asymptomatic Ratio of Norovirus Infection During Foodborne Outbreaks With Laboratory Testing in Japan

• Published in: Journal of epidemiology Vol. 28; no. 9; pp. 382 - 387
• Main Authors: Miura, Fuminari, Matsuyama, Ryota, Nishiura, Hiroshi
• Format: Journal Article
• Language: English
• Published: Japan Japan Epidemiological Association 05.09.2018
• Subjects: Asymptomatic Diseases - epidemiology; asymptomatic ratio; Caliciviridae; Caliciviridae Infections - epidemiology; Clinical Laboratory Techniques - statistics & numerical data; Confidence intervals; Disease Outbreaks; Foodborne diseases; Foodborne Diseases - epidemiology; Genotype; Genotype & phenotype; Genotypes; Health risks; Humans; Infections; Infectious Disease; Japan - epidemiology; Laboratory tests; mathematical model; Mathematical models; Maximum likelihood estimation; Models, Statistical; Norovirus; Norovirus - genetics; Norovirus - isolation & purification; Norwalk virus; Original; Outbreaks; Random sampling; Statistical analysis; statistical estimation; Statistical methods; Statistical models; Statistical sampling; subclinical infection; Surveillance; Viruses; Japan; mathematical model; statistical estimation; subclinical infection; asymptomatic ratio; Caliciviridae; Norwalk virus

Foodborne norovirus outbreak data in Japan from 2005-2006, involving virological surveillance of all symptomatic and asymptomatic individuals, were reanalyzed to estimate the asymptomatic ratio of norovirus infection along with the risk of infection and the probability of virus shedding. Employing a...