MDM2 Acts Downstream of p53 as an E3 Ligase to Promote FOXO Ubiquitination and Degradation - Fu, Wei; Ma, Qiuping; Chen, Lei; Li, Pengfei; Zhang, Mu; Ramamoorthy, Sivapriya; Nawaz, Zafar; Shimojima, Tsukasa; Wang, Hengbin; Yang, Yonghua; Shen, Zheng; Zhang, Yingtao; et al. (The Journal of biological chemistry, 2009)
Keywords: Animals; Apoptosis; Cell Line; Cell Nucleus - metabolism; Cytoprotection; Forkhead Transcription Factors - metabolism; Gene Expression Regulation; Humans; Mechanisms of Signal Transduction; Mice; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Transport; Proto-Oncogene Proteins c-akt - metabolism; Proto-Oncogene Proteins c-mdm2 - chemistry; Proto-Oncogene Proteins c-mdm2 - metabolism; Tumor Suppressor Protein p53 - metabolism; Ubiquitin-Protein Ligases - metabolism; Ubiquitination