Bluetongue virus: dissection of the polymerase complex

• Published in: Journal of general virology Vol. 89; no. 8; pp. 1789 - 1804
• Main Author: Roy, Polly
• Format: Journal Article
• Language: English
• Published: Reading Soc General Microbiol 01.08.2008; Society for General Microbiology
• Subjects: Animals; Animals, Domestic - virology; Animals, Wild - virology; Biological and medical sciences; Bluetongue - transmission; Bluetongue - virology; Bluetongue virus; Bluetongue virus - genetics; Bluetongue virus - metabolism; Bluetongue virus - ultrastructure; capsid; Ceratopogonidae - virology; DNA-Directed RNA Polymerases - chemistry; DNA-Directed RNA Polymerases - genetics; DNA-Directed RNA Polymerases - metabolism; double-stranded RNA; Fundamental and applied biological sciences. Psychology; literature reviews; Microbiology; Miscellaneous; Models, Molecular; mRNA capping enzymes; Orbivirus; polymerase complex; Reoviridae; RNA helicases; RNA, Viral - metabolism; RNA-directed RNA polymerase; Ruminantia; viral proteins; Viral Proteins - chemistry; Viral Proteins - genetics; Viral Proteins - metabolism; Virology; virus replication; Virus; Microbiology; Veterinary; Reoviridae; Orbivirus; Bluetongue virus

Bluetongue is a vector-borne viral disease of ruminants that is endemic in tropical and subtropical countries. Since 1998 the virus has also appeared in Europe. Partly due to the seriousness of the disease, bluetongue virus (BTV), a member of genus Orbivirus within the family Reoviridae, has been a...