Bioavailability of tomato polyphenols is enhanced by processing and fat addition: Evidence from a randomized feeding trial

• Published in: Molecular nutrition & food research Vol. 60; no. 7; pp. 1578 - 1589
• Main Authors: Martínez-Huélamo, Miriam, Vallverdú-Queralt, Anna, Di Lecce, Giuseppe, Valderas-Martínez, Palmira, Tulipani, Sara, Jáuregui, Olga, Escribano-Ferrer, Elvira, Estruch, Ramón, Illan, Montse, Lamuela-Raventós, Rosa M.
• Format: Journal Article
• Language: English
• Published: Germany Blackwell Publishing Ltd 01.07.2016; Wiley-VCH Verlag
• Subjects: Adolescent; Adult; bioavailability; Biological Availability; coumaric acids; Coumaric Acids - blood; Coumaric Acids - pharmacokinetics; Cross-Over Studies; Female; flavanols; flavanones; Flavanones - blood; Flavanones - pharmacokinetics; flavonols; Flavonols - blood; Flavonols - pharmacokinetics; Food and Nutrition; Half-Life; health promotion; Humans; ingestion; intestinal absorption; intestinal microorganisms; Life Sciences; Lycopersicon esculentum; Lycopersicon esculentum - chemistry; Male; metabolism; metabolites; Microbiota metabolites; Naringenin; Olea; Olive oil; Olive Oil - administration & dosage; Pharmacokinetics; polyphenols; Polyphenols - blood; Polyphenols - pharmacokinetics; small intestine; Tomato sauce; tomatoes; urine; Vegetal Biology; volunteers; Young Adult; Naringenin; Tomato sauce; Olive oil; Pharmacokinetics; Microbiota metabolites; microbial metabolism; biodisponibilité; urine; tomato sauce; micromass; concentration plasmatique; phenolic compound; huile d'olive; sauce tomate; human health; flavanol; composé phénolique; naringenin; métabolisme microbien; bioavailability; santé humaine; pharmacokinetics; flavanone; olive oil; plasma; microbiota metabolites

Scope Tomato contains a variety of phenolics associated with health‐promoting properties. However, the effects of processing and the addition of oil during tomato sauce preparation on microbial metabolism of phenolics in the small intestine are still unclear. Methods and results An open, controlled,...