Matrix metalloproteinases-2 and -9 in cervical cancer: different roles in tumor progression

• Published in: International journal of gynecological cancer Vol. 16; no. 3; p. 1297
• Main Authors: Rauvala, M, Aglund, K, Puistola, U, Turpeenniemi-Hujanen, T, Horvath, G, Willén, R, Stendahl, U
• Format: Journal Article
• Language: English
• Published: England 01.05.2006
• Subjects: Adult; Aged; Aged, 80 and over; Carcinoma - enzymology; Carcinoma - pathology; Contraceptive Agents, Female - pharmacology; Disease Progression; Female; Humans; Matrix Metalloproteinase 2 - physiology; Matrix Metalloproteinase 9 - physiology; Middle Aged; Parity; Pregnancy; Retrospective Studies; Sexual Behavior - statistics & numerical data; Survival Rate; Uterine Cervical Neoplasms - enzymology; Uterine Cervical Neoplasms - pathology

The incidence of uterine cervical cancer has increased slightly in Western countries, with an increase in relatively young women. Overexpression of matrix metalloproteinases (MMPs)-2 and -9 has turned out as a prognostic factor in many cancers. We compared the expression of the proteins MMP-2 and MM...