Epidermal growth factor receptor-tyrosine kinase inhibitor (gefitinib) augments pneumonitis, but attenuates lung fibrosis in response to radiation injury in rats - Toyoda, Yuko; Yuasa, Shino; Aono, Yoshinori; Suzuka, Chiyuki; Tezuka, Toshifumi; Tani, Kenji; Miyake, Keiko; Kishi, Jun; Hanibuchi, Masaki; Sone, Saburo; Nishioka, Yasuhiko; Kakiuchi, Soji (The Journal of Medical Investigation, 2012)
Keywords: Animals; Disease Models, Animal; epidermal growth factor receptor; gefitinib; Male; Protein Kinase Inhibitors - pharmacology; Pulmonary Fibrosis - drug therapy; Pulmonary Fibrosis - pathology; Quinazolines - pharmacology; radiation pneumonitis; Radiation Pneumonitis - drug therapy; Radiation Pneumonitis - pathology; Rats; Rats, Wistar; Receptor, Epidermal Growth Factor - antagonists & inhibitors