Combination therapy with cannabidiol and chemotherapeutics in canine urothelial carcinoma cells

• Published in: PloS one Vol. 16; no. 8; p. e0255591
• Main Authors: Inkol, Jordon M, Hocker, Samuel E, Mutsaers, Anthony J
• Format: Journal Article
• Language: English
• Published: San Francisco, CA USA Public Library of Science 05.08.2021; Public Library of Science (PLoS)
• Subjects: Biology and Life Sciences; Bladder cancer; Chemotherapy, Combination; Diseases; Dogs; Drug therapy; Medicine and Health Sciences; Methods; Mitoxantrone hydrochloride; Vinblastine; Canada

Canine urothelial carcinoma is the most common form of canine bladder cancer. Treatment with chemotherapy has variable response rates leading to most dogs succumbing to their disease within a year. Cannabidiol is an emerging treatment within the field of oncology. In reported in vivo studies, cannab...