Impact of a double dose of sulphadoxine–pyrimethamine to reduce prevalence of pregnancy malaria in southern Mozambique

• Published in: Tropical medicine & international health Vol. 9; no. 10; pp. 1066 - 1073
• Main Authors: Challis, K., Osman, N. B., Cotiro, M., Nordahl, G., Dgedge, M., Bergström, S.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.10.2004; Blackwell Science; Blackwell Publishing Ltd
• Subjects: abortion; Adolescent; Adult; Antimalarials - adverse effects; Antimalarials - therapeutic use; Biological and medical sciences; Birth Weight; Comparative studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug therapy; Female; Human protozoal diseases; Humans; Infectious diseases; Malaria; Malaria - prevention & control; malaria peripheral parasitaemia; Medical research; Medical sciences; Medicin och hälsovetenskap; Mozambique; newborn status; Parasitemia - prevention & control; Parasitic diseases; Patient Selection; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic - prevention & control; Pregnancy Outcome; Prenatal Care - methods; pre‐term delivery and low birthweight; Protozoal diseases; Pyrimethamine - adverse effects; Pyrimethamine - therapeutic use; side‐effects; Sulfadoxine - adverse effects; Sulfadoxine - therapeutic use; sulphadoxine–pyrimethamine; Teenagers; Mozambique; Africa; Sulfanilamide derivatives; Human; Antimalarial; Protozoal disease; Sulfonamide; Prevalence; Malaria; Pyrimethamine; Parasitosis; Infection; Pregnancy; Chemotherapy; Treatment; Parasiticide; Tropical medicine; Antiinfectious; Sulfadoxine

Summary Malarial infection during pregnancy increases the risks of severe sequelae for the pregnant woman and the risk of delivering a low birthweight baby. The aim of this intervention study was to reduce significantly the prevalence of malaria parasitaemia in adolescent parturients in Matola and B...