Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors - Wang, Xiaoling; Wang, Yebo; Wu, Xiwei; Wang, Jinhui; Wang, Yingjia; Qiu, Zhaojun; Chang, Tammy; Huang, He; Lin, Ren-Jang; Yee, Jiing-Kuan (Nature biotechnology, 2015)
Keywords: 42; 45; 45/41; 631/1647/1511; 631/1647/1513/1967; 631/1647/1513/1967/2316; 631/1647/514/1948; Agriculture; Bioinformatics; Biomedical Engineering/Biotechnology; Biomedicine; Biotechnology; brief-communication; CRISPR-Cas Systems - genetics; Genetic engineering; Genetic research; Genetic Vectors; Genome, Human; Genomes; Genomics; HEK293 Cells; High-Throughput Nucleotide Sequencing; Humans; Integrases - genetics; Lentivirus; Lentivirus - enzymology; Lentivirus - genetics; Life Sciences; Methods; Nucleotide sequence; Ribonucleic acid; RNA; RNA Editing - genetics