Circulating MicroRNAs and Aerobic Fitness – The HUNT-Study

• Published in: PloS one Vol. 8; no. 2; p. e57496
• Main Authors: Bye, Anja, Røsjø, Helge, Aspenes, Stian T., Condorelli, Gianluigi, Omland, Torbjørn, Wisløff, Ulrik
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 28.02.2013; Public Library of Science (PLoS)
• Subjects: Adult; Atherosclerosis; Bioindicators; Biology; Biomarkers; Blood; Blood pressure; Cardiology; Cardiorespiratory fitness; Cardiovascular diseases; Cholesterol; Cohort Studies; Exercise; Female; Fitness; Gene expression; Glucose; Heart attacks; Heart failure; Hospitals; Humans; Hypoxia; Kinases; Male; Medical imaging; Medicine; MicroRNAs; MicroRNAs - blood; miRNA; Mortality; Oxygen; Oxygen Consumption; Oxygen uptake; Physical activity; Physical Fitness; Risk analysis; Risk factors; Signalling systems; Smoking; Target recognition; Triglycerides; Norway; Italy

Aerobic fitness, measured as maximal oxygen uptake (VO2max), is a good indicator of cardiovascular health, and a strong predictor of cardiovascular mortality. Biomarkers associated with low VO2max may therefore represent potential early markers of future cardiovascular disease (CVD). The aim of this...