Association of interleukin 22 receptor subunit alpha 1 gene polymorphisms with chronic rhinosinusitis

• Published in: Brazilian journal of otorhinolaryngology Vol. 87; no. 5; pp. 505 - 511
• Main Authors: Dinarte, Vanessa R. Pires, Silva, Wilson A., Baccarin, Anemari R.D., Tamashiro, Edwin, Valera, Fabiana C., Anselmo-Lima, Wilma T.
• Format: Journal Article
• Language: English
• Published: Brazil Elsevier Editora Ltda 01.09.2021; Elsevier; Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial
• Subjects: Chronic Disease; Chronic rhinosinusitis; Humans; Interleukins; Nasal polyps; Nasal Polyps - genetics; Original; OTORHINOLARYNGOLOGY; Polymorphism, Genetic; Polymorphisms; Receptors, Interleukin; Rhinitis - genetics; Sinusitis - genetics; Nasal polyps; Polymorphisms; Chronic rhinosinusitis; Pólipos nasais; Rinossinusite crônica; Polimorfismos

Chronic rhinosinusitis is a multifactorial disease whose pathogenesis, influenced by both genetic and environmental factors, is still unclear. Previous genetic studies have shown that patients with chronic rhinosinusitis have reduced expression of the Interleukin-22 (IL-22) gene. Identify and compar...