Cytokines in the pathogenesis of atherosclerosis

• Published in: Thrombosis and haemostasis Vol. 88; no. 4; p. 554
• Main Authors: Young, James L, Libby, Peter, Schönbeck, Uwe
• Format: Journal Article
• Language: English
• Published: Germany 01.10.2002
• Subjects: Arteriosclerosis - etiology; Arteriosclerosis - immunology; Arteriosclerosis - pathology; Cytokines - physiology; Humans; Inflammation - immunology; Interferons - physiology; Interleukins - physiology; Tumor Necrosis Factor-alpha - physiology

Research during the last two decades established atheromatous lesions as active sites of inflammation and immune responses, contrasting to the traditional view of atherosclerosis as an acellular lesion composed of lipid deposits. In particular, cytokines appear to orchestrate the chronic development...