Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair - Lafrance-Vanasse, Julien; Williams, Gareth J.; Tainer, John A. (Progress in biophysics and molecular biology, 2015)
Keywords: Acid Anhydride Hydrolases; Allostery; Cell Cycle Proteins - chemistry; Cell Cycle Proteins - genetics; Cell Cycle Proteins - ultrastructure; Conformational change; CtIP; DNA - chemistry; DNA - genetics; DNA - ultrastructure; DNA Damage - genetics; DNA Repair - genetics; DNA Repair Enzymes - chemistry; DNA Repair Enzymes - genetics; DNA Repair Enzymes - ultrastructure; DNA Replication - genetics; DNA-Binding Proteins - chemistry; DNA-Binding Proteins - genetics; DNA-Binding Proteins - ultrastructure; Double strand break repair; Dynamics; Humans; Models, Biological; Models, Chemical; Models, Molecular; MRE11 Homologue Protein; Mre11-Rad50-Nbs1; Nuclear Proteins - chemistry; Nuclear Proteins - genetics; Nuclear Proteins - ultrastructure; Nucleic Acid Conformation; Protein Binding; Protein Conformation; Structure-Activity Relationship; Mre11-Rad50-Nbs1; AFM; EM; MRN; Allostery; HRR; Conformational change; SAXS; Double strand break repair; DSB; Dynamics; CtIP; ATM; NHEJ; BRCT; FHA; ATR; DSBR