Quantifying six-minute walk induced gait deterioration with inertial sensors in multiple sclerosis subjects

• Published in: Gait & posture Vol. 49; no. NA; pp. 340 - 345
• Main Authors: Engelhard, Matthew M., Dandu, Sriram Raju, Patek, Stephen D., Lach, John C., Goldman, Myla D.
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.09.2016
• Subjects: Accelerometry; Adolescent; Adult; Body-worn sensors; Disabled Persons - rehabilitation; Disease Progression; Dynamic time warping; Exercise Therapy - methods; Female; Humans; Male; Middle Aged; Mobility Limitation; Multiple sclerosis; Multiple Sclerosis - diagnosis; Multiple Sclerosis - physiopathology; Multiple Sclerosis - rehabilitation; Muscle Fatigue - physiology; Orthopedics; Six-minute walk; Time Factors; Walking - physiology; Walking impairment; Walking Speed - physiology; Young Adult; Multiple sclerosis; Six-minute walk; Body-worn sensors; Dynamic time warping; Walking impairment

•A sensor-based measure of gait deterioration is validated in multiple sclerosis subjects.•This measure – the Warp Score – quantifies gait cycle “stretching” induced by the six-minute walk.•Warp Scores correlate with patient-reported fatigue even after controlling for walking speed.•Measurable evide...