Preliminary pediatric clinical evaluation of the oral probiotic Streptococcus salivarius K12 in preventing recurrent pharyngitis and/or tonsillitis caused by Streptococcus pyogenes and recurrent acute otitis media

• Published in: International journal of general medicine Vol. 5; no. default; pp. 991 - 997
• Main Authors: Di Pierro, Francesco, Donato, Guido, Fomia, Federico, Adami, Teresa, Careddu, Domenico, Cassandro, Albera, Roberto
• Format: Journal Article
• Language: English
• Published: New Zealand Dove Medical Press Limited 01.01.2012; Taylor & Francis Ltd; Dove Press; Dove Medical Press
• Subjects: acute otitis media; bacteriocin-like inhibitory substance K12; Bactoblis; BLIS K12; Control; Ear diseases; Growth; Infections; Original Research; Otitis media; Pathology; Pharyngitis; Prevention; Probiotics; Streptococcus; Streptococcus infections; Streptococcus salivarius K12; Tonsillitis; New Zealand; acute otitis media; pharyngitis; bacteriocin-like inhibitory substance K12; Streptococcus salivarius K12; BLIS K12; tonsillitis; Bactoblis

The oral probiotic Streptococcus salivarius K12 has been shown clearly to antagonize the growth of Streptococcus pyogenes, the most important bacterial cause of pharyngeal infections in humans, by releasing two bacteriocins named salivaricin A2 and salivaricin B. Unpublished observations indicate th...