Proteomic profiling of cerebrospinal fluid identifies biomarkers for amyotrophic lateral sclerosis - Ranganathan, Srikanth; Williams, Eric; Ganchev, Philip; Gopalakrishnan, Vanathi; Lacomis, David; Urbinelli, Leo; Newhall, Kristyn; Cudkowicz, Merit E.; Brown, Robert H.; Bowser, Robert (Journal of neurochemistry, 2005)
Keywords: Adult; Algorithms; Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis - cerebrospinal fluid; Biological and medical sciences; Biomarkers - cerebrospinal fluid; Body fluids; cerebrospinal fluid; Cerebrospinal fluid. Meninges. Spinal cord; Comparative studies; Cystatin C; Cystatins - cerebrospinal fluid; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Female; Humans; Hypotheses; Immunohistochemistry - methods; Juniperus - metabolism; Male; mass spectrometry; Medical sciences; Middle Aged; Motor Neurons - metabolism; Nervous system (semeiology, syndromes); Neuroendocrine Secretory Protein 7B2 - cerebrospinal fluid; Neurology; Prealbumin - cerebrospinal fluid; Proteins; Proteomics; Proteomics - methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods; Spinal Cord - pathology; Immunohistochemistry; Nervous system diseases; proteomics; Pathogenesis; Ions; Amyotrophic lateral sclerosis; Motor neuron; Cerebrospinal fluid; Protein; Central nervous system disease; Predictive value; Degenerative disease; Degeneration; Spinal cord disease; Learning algorithm; Mass spectrometry; Algorithm analysis