Profiling of 95 MicroRNAs in Pancreatic Cancer Cell Lines and Surgical Specimens by Real-Time PCR Analysis

• Published in: World journal of surgery Vol. 33; no. 4; pp. 698 - n/a
• Main Authors: Zhang, Yuqing, Li, Min, Wang, Hao, Fisher, William E., Lin, Peter H., Yao, Qizhi, Chen, Changyi
• Format: Journal Article
• Language: English
• Published: New York Springer-Verlag 01.04.2009; Springer‐Verlag; John Wiley & Sons, Inc
• Subjects: Abdominal Surgery; Carcinoma, Pancreatic Ductal - genetics; Cardiac Surgery; Cell Line, Tumor - chemistry; Chronic Pancreatitis; Databases, Nucleic Acid; Gene Expression Profiling; General Surgery; Humans; Medicine; Medicine & Public Health; Microarray Analysis; MicroRNAs - analysis; MicroRNAs - metabolism; miRNA Expression; Oligonucleotide Array Sequence Analysis; Pancreatic Cancer; Pancreatic Cancer Cell Line; Pancreatic Cancer Tissue; Pancreatic Neoplasms - genetics; Pancreatitis - genetics; Pancreatitis - metabolism; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm - analysis; Surgery; Thoracic Surgery; Tissue Array Analysis; Vascular Surgery; miRNA Expression; Pancreatic Cancer Cell Line; Chronic Pancreatitis; Pancreatic Cancer; Pancreatic Cancer Tissue

Background MicroRNAs (miRNAs) are involved in cancer pathogenesis, apoptosis, and cell growth, thereby functioning as tumor suppressors or oncogenes. However, expression alterations and roles of these miRNAs in pancreatic cancer are largely unknown. We hypothesized that pancreatic cancer may have a...