Roscovitine, a novel cyclin‐dependent kinase inhibitor, characterizes restriction point and G2/M transition in tobacco BY‐2 cell suspension

• Published in: The Plant journal : for cell and molecular biology Vol. 12; no. 1; pp. 191 - 202
• Main Authors: Planchais, Séverine, Glab, Nathalie, Tréhin, Christophe, Perennes, Claudette, Bureau, Jean‐Marc, Meijer, Laurent, Bergounioux, Catherine
• Format: Journal Article
• Language: English
• Published: Osney Mead, Oxford OX2 0EL, UK Blackwell Science Ltd 01.07.1997; Blackwell Science
• Subjects: 2,4-Dichlorophenoxyacetic Acid - pharmacology; Aphidicolin - pharmacology; Biological and medical sciences; Cell Cycle - drug effects; Cell cycle, cell proliferation; Cell physiology; Cells, Cultured; Cyclin-Dependent Kinases - antagonists & inhibitors; Cyclin-Dependent Kinases - biosynthesis; Enzyme Inhibitors - pharmacology; Fundamental and applied biological sciences. Psychology; G2 Phase; Mitosis; Molecular and cellular biology; Nicotiana - cytology; Nicotiana - drug effects; Nicotiana - physiology; Nicotiana tabacum; Plants, Toxic; Protamine Kinase - antagonists & inhibitors; Protamine Kinase - biosynthesis; Purines - pharmacology; Roscovitine; Enzyme; Mitosis; Transferases; Cyclin; Enzyme inhibitor; Stimulant plant; Nicotiana tabacum; Protamine kinase; Enzymatic activity; Kinase; Dicotyledones; Angiospermae; Cell cycle; Immunoblotting assay; G2 Phase; Spermatophyta; Solanaceae

Summary Although the developmental programs of plants and animals differ, key regulatory components of their cell cycle have been conserved. Particular attention has been paid to the role of the complexes between highly conserved cyclin and cyclin‐dependent kinases in regulating progression through...