High-risk human papillomavirus status and prognosis in invasive cervical cancer: A nationwide cohort study

• Published in: PLoS medicine Vol. 15; no. 10; p. e1002666
• Main Authors: Lei, Jiayao, Ploner, Alexander, Lagheden, Camilla, Eklund, Carina, Nordqvist Kleppe, Sara, Andrae, Bengt, Elfström, K Miriam, Dillner, Joakim, Sparén, Pär, Sundström, Karin
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.10.2018; Public Library of Science (PLoS)
• Subjects: Age; Bioindicators; Biology and life sciences; Cervical cancer; Cervix; Cohort analysis; Diagnosis; Genotyping; Gynecology; Health risk assessment; Health risks; Human papillomavirus; Invasiveness; Laboratories; Medicin och hälsovetenskap; Medicine and Health Sciences; Migration; Mortality; Obstetrics; Paraffin; Poisson density functions; Population studies; Prognosis; Squamous cell carcinoma; Studies; Tumors; Sweden

High-risk human papillomavirus (hrHPV) infection is established as the major cause of invasive cervical cancer (ICC). However, whether hrHPV status in the tumor is associated with subsequent prognosis of ICC is controversial. We aim to evaluate the association between tumor hrHPV status and ICC prog...