Dexmedetomidine pretreatment alleviates cerebral ischemia/reperfusion injury by inhibiting neuroinflammation through the JAK2/STAT3 pathway - Liu, Huan; Li, Jianli; Jiang, Li; He, Jinhua; Zhang, Huanhuan; Wang, Keyan (Brazilian journal of medical and biological research, 2022)
Keywords: BIOLOGY; Brain injury; Cellular signal transduction; Cerebral blood flow; Cerebral infarction; Cerebral ischemia; Cerebral ischemia/reperfusion injury; Dexmedetomidine; Dosage and administration; Drug therapy; Health aspects; Inflammation; Interleukin 6; Ischemia; JAK2/STAT3 signaling pathway; Janus kinase 2; MEDICINE, RESEARCH & EXPERIMENTAL; Neuroprotection; Prevention; Reperfusion; Reperfusion injury; Signal transduction; Specific pathogen free; Stat3 protein; Testing; Tumor necrosis factor-α; Western blotting; China; Neuroprotection; Inflammation; Cerebral ischemia/reperfusion injury; Dexmedetomidine; JAK2/STAT3 signaling pathway