Clinical Features and Outcomes of Neuropsychiatric Systemic Lupus Erythematosus in China
Objective. To identify the clinical characteristics, magnetic resonance imaging (MRI) results, and prognostic factors of neuropsychiatric (NP) systemic lupus erythematosus (SLE; NPSLE) in a relatively large patient series in China. Methods. Data of patients with NPSLE at Peking Union Medical College...
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| Published in | Journal of Immunology Research Vol. 2021; pp. 1 - 10 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
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Egypt
Hindawi
18.01.2021
John Wiley & Sons, Inc Wiley |
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| Abstract | Objective. To identify the clinical characteristics, magnetic resonance imaging (MRI) results, and prognostic factors of neuropsychiatric (NP) systemic lupus erythematosus (SLE; NPSLE) in a relatively large patient series in China. Methods. Data of patients with NPSLE at Peking Union Medical College Hospital (PUMCH) were collected retrospectively from June 2012 to June 2016. NPSLE patients were compared with 220 non-NPSLE patients. Survival rates were evaluated using the Kaplan-Meier curves, log-rank test, and Cox proportional hazards modeling. Cranial MRI results were also studied. Results. Of the 194 included patients, sixteen subtypes of NPSLE were identified, and the most common manifestations were seizure (36.6%), acute confusional state (25.3%), and cerebral vascular disease (15.5%). Compared with the non-NPSLE group, NPSLE patients were significantly more likely to have typical lupus symptoms, higher Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) scores (P=0.002), and positive rate of anti-ribosomal P protein antibodies (P=0.008). Patients with seizure were more likely to have higher SLEDAI-2K scores and positive anti-β2GP1 than non-NPSLE patients. Sixteen patients died during follow-up. The most common cause of death was infection (37.5%). NPSLE significantly decreased survival rates of SLE patients. Patients with elevated serum creatinine (P=0.001), hypocomplementemia (P=0.031), and SLEDAI−2K scores≥15 (P=0.014) had shorter survival periods. Eighty-two patients underwent detailed cranial MRI analysis; of these, 50 (61.0%) had abnormal results. Small vessel disease was the most common abnormal finding, followed by inflammatory-like lesions and large vessel disease. Conclusions. High disease activity and positive rate of anti-ribosomal P protein antibodies may be risk factors for NPSLE. NPSLE decreases survival rates of SLE patients. Renal insufficiency and high disease activity are predictive of poor prognoses for NPSLE patients. |
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| AbstractList | Objective. To identify the clinical characteristics, magnetic resonance imaging (MRI) results, and prognostic factors of neuropsychiatric (NP) systemic lupus erythematosus (SLE; NPSLE) in a relatively large patient series in China. Methods. Data of patients with NPSLE at Peking Union Medical College Hospital (PUMCH) were collected retrospectively from June 2012 to June 2016. NPSLE patients were compared with 220 non-NPSLE patients. Survival rates were evaluated using the Kaplan-Meier curves, log-rank test, and Cox proportional hazards modeling. Cranial MRI results were also studied. Results. Of the 194 included patients, sixteen subtypes of NPSLE were identified, and the most common manifestations were seizure (36.6%), acute confusional state (25.3%), and cerebral vascular disease (15.5%). Compared with the non-NPSLE group, NPSLE patients were significantly more likely to have typical lupus symptoms, higher Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) scores (P=0.002), and positive rate of anti-ribosomal P protein antibodies (P=0.008). Patients with seizure were more likely to have higher SLEDAI-2K scores and positive anti-β2GP1 than non-NPSLE patients. Sixteen patients died during follow-up. The most common cause of death was infection (37.5%). NPSLE significantly decreased survival rates of SLE patients. Patients with elevated serum creatinine (P=0.001), hypocomplementemia (P=0.031), and SLEDAI−2K scores≥15 (P=0.014) had shorter survival periods. Eighty-two patients underwent detailed cranial MRI analysis; of these, 50 (61.0%) had abnormal results. Small vessel disease was the most common abnormal finding, followed by inflammatory-like lesions and large vessel disease. Conclusions. High disease activity and positive rate of anti-ribosomal P protein antibodies may be risk factors for NPSLE. NPSLE decreases survival rates of SLE patients. Renal insufficiency and high disease activity are predictive of poor prognoses for NPSLE patients. To identify the clinical characteristics, magnetic resonance imaging (MRI) results, and prognostic factors of neuropsychiatric (NP) systemic lupus erythematosus (SLE; NPSLE) in a relatively large patient series in China. Data of patients with NPSLE at Peking Union Medical College Hospital (PUMCH) were collected retrospectively from June 2012 to June 2016. NPSLE patients were compared with 220 non-NPSLE patients. Survival rates were evaluated using the Kaplan-Meier curves, log-rank test, and Cox proportional hazards modeling. Cranial MRI results were also studied. Of the 194 included patients, sixteen subtypes of NPSLE were identified, and the most common manifestations were seizure (36.6%), acute confusional state (25.3%), and cerebral vascular disease (15.5%). Compared with the non-NPSLE group, NPSLE patients were significantly more likely to have typical lupus symptoms, higher Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) scores ( = 0.002), and positive rate of anti-ribosomal P protein antibodies ( = 0.008). Patients with seizure were more likely to have higher SLEDAI-2K scores and positive anti- 2GP1 than non-NPSLE patients. Sixteen patients died during follow-up. The most common cause of death was infection (37.5%). NPSLE significantly decreased survival rates of SLE patients. Patients with elevated serum creatinine ( = 0.001), hypocomplementemia ( = 0.031), and SLEDAI - 2K scores ≥ 15 ( = 0.014) had shorter survival periods. Eighty-two patients underwent detailed cranial MRI analysis; of these, 50 (61.0%) had abnormal results. Small vessel disease was the most common abnormal finding, followed by inflammatory-like lesions and large vessel disease. High disease activity and positive rate of anti-ribosomal P protein antibodies may be risk factors for NPSLE. NPSLE decreases survival rates of SLE patients. Renal insufficiency and high disease activity are predictive of poor prognoses for NPSLE patients. Objective. To identify the clinical characteristics, magnetic resonance imaging (MRI) results, and prognostic factors of neuropsychiatric (NP) systemic lupus erythematosus (SLE; NPSLE) in a relatively large patient series in China. Methods. Data of patients with NPSLE at Peking Union Medical College Hospital (PUMCH) were collected retrospectively from June 2012 to June 2016. NPSLE patients were compared with 220 non-NPSLE patients. Survival rates were evaluated using the Kaplan-Meier curves, log-rank test, and Cox proportional hazards modeling. Cranial MRI results were also studied. Results. Of the 194 included patients, sixteen subtypes of NPSLE were identified, and the most common manifestations were seizure (36.6%), acute confusional state (25.3%), and cerebral vascular disease (15.5%). Compared with the non-NPSLE group, NPSLE patients were significantly more likely to have typical lupus symptoms, higher Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) scores (P=0.002), and positive rate of anti-ribosomal P protein antibodies (P=0.008). Patients with seizure were more likely to have higher SLEDAI-2K scores and positive anti-β 2GP1 than non-NPSLE patients. Sixteen patients died during follow-up. The most common cause of death was infection (37.5%). NPSLE significantly decreased survival rates of SLE patients. Patients with elevated serum creatinine (P=0.001), hypocomplementemia (P=0.031), and SLEDAI-2Kscores≥15 (P=0.014) had shorter survival periods. Eighty-two patients underwent detailed cranial MRI analysis; of these, 50 (61.0%) had abnormal results. Small vessel disease was the most common abnormal finding, followed by inflammatory-like lesions and large vessel disease. Conclusions. High disease activity and positive rate of anti-ribosomal P protein antibodies may be risk factors for NPSLE. NPSLE decreases survival rates of SLE patients. Renal insufficiency and high disease activity are predictive of poor prognoses for NPSLE patients. Objective. To identify the clinical characteristics, magnetic resonance imaging (MRI) results, and prognostic factors of neuropsychiatric (NP) systemic lupus erythematosus (SLE; NPSLE) in a relatively large patient series in China. Methods. Data of patients with NPSLE at Peking Union Medical College Hospital (PUMCH) were collected retrospectively from June 2012 to June 2016. NPSLE patients were compared with 220 non-NPSLE patients. Survival rates were evaluated using the Kaplan-Meier curves, log-rank test, and Cox proportional hazards modeling. Cranial MRI results were also studied. Results. Of the 194 included patients, sixteen subtypes of NPSLE were identified, and the most common manifestations were seizure (36.6%), acute confusional state (25.3%), and cerebral vascular disease (15.5%). Compared with the non-NPSLE group, NPSLE patients were significantly more likely to have typical lupus symptoms, higher Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) scores ( P = 0.002 ), and positive rate of anti-ribosomal P protein antibodies ( P = 0.008 ). Patients with seizure were more likely to have higher SLEDAI-2K scores and positive anti-β2GP1 than non-NPSLE patients. Sixteen patients died during follow-up. The most common cause of death was infection (37.5%). NPSLE significantly decreased survival rates of SLE patients. Patients with elevated serum creatinine ( P = 0.001 ), hypocomplementemia ( P = 0.031 ), and SLEDAI − 2 K scores ≥ 15 ( P = 0.014 ) had shorter survival periods. Eighty-two patients underwent detailed cranial MRI analysis; of these, 50 (61.0%) had abnormal results. Small vessel disease was the most common abnormal finding, followed by inflammatory-like lesions and large vessel disease. Conclusions. High disease activity and positive rate of anti-ribosomal P protein antibodies may be risk factors for NPSLE. NPSLE decreases survival rates of SLE patients. Renal insufficiency and high disease activity are predictive of poor prognoses for NPSLE patients. To identify the clinical characteristics, magnetic resonance imaging (MRI) results, and prognostic factors of neuropsychiatric (NP) systemic lupus erythematosus (SLE; NPSLE) in a relatively large patient series in China.OBJECTIVETo identify the clinical characteristics, magnetic resonance imaging (MRI) results, and prognostic factors of neuropsychiatric (NP) systemic lupus erythematosus (SLE; NPSLE) in a relatively large patient series in China.Data of patients with NPSLE at Peking Union Medical College Hospital (PUMCH) were collected retrospectively from June 2012 to June 2016. NPSLE patients were compared with 220 non-NPSLE patients. Survival rates were evaluated using the Kaplan-Meier curves, log-rank test, and Cox proportional hazards modeling. Cranial MRI results were also studied.METHODSData of patients with NPSLE at Peking Union Medical College Hospital (PUMCH) were collected retrospectively from June 2012 to June 2016. NPSLE patients were compared with 220 non-NPSLE patients. Survival rates were evaluated using the Kaplan-Meier curves, log-rank test, and Cox proportional hazards modeling. Cranial MRI results were also studied.Of the 194 included patients, sixteen subtypes of NPSLE were identified, and the most common manifestations were seizure (36.6%), acute confusional state (25.3%), and cerebral vascular disease (15.5%). Compared with the non-NPSLE group, NPSLE patients were significantly more likely to have typical lupus symptoms, higher Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) scores (P = 0.002), and positive rate of anti-ribosomal P protein antibodies (P = 0.008). Patients with seizure were more likely to have higher SLEDAI-2K scores and positive anti-β2GP1 than non-NPSLE patients. Sixteen patients died during follow-up. The most common cause of death was infection (37.5%). NPSLE significantly decreased survival rates of SLE patients. Patients with elevated serum creatinine (P = 0.001), hypocomplementemia (P = 0.031), and SLEDAI - 2K scores ≥ 15 (P = 0.014) had shorter survival periods. Eighty-two patients underwent detailed cranial MRI analysis; of these, 50 (61.0%) had abnormal results. Small vessel disease was the most common abnormal finding, followed by inflammatory-like lesions and large vessel disease.RESULTSOf the 194 included patients, sixteen subtypes of NPSLE were identified, and the most common manifestations were seizure (36.6%), acute confusional state (25.3%), and cerebral vascular disease (15.5%). Compared with the non-NPSLE group, NPSLE patients were significantly more likely to have typical lupus symptoms, higher Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) scores (P = 0.002), and positive rate of anti-ribosomal P protein antibodies (P = 0.008). Patients with seizure were more likely to have higher SLEDAI-2K scores and positive anti-β2GP1 than non-NPSLE patients. Sixteen patients died during follow-up. The most common cause of death was infection (37.5%). NPSLE significantly decreased survival rates of SLE patients. Patients with elevated serum creatinine (P = 0.001), hypocomplementemia (P = 0.031), and SLEDAI - 2K scores ≥ 15 (P = 0.014) had shorter survival periods. Eighty-two patients underwent detailed cranial MRI analysis; of these, 50 (61.0%) had abnormal results. Small vessel disease was the most common abnormal finding, followed by inflammatory-like lesions and large vessel disease.High disease activity and positive rate of anti-ribosomal P protein antibodies may be risk factors for NPSLE. NPSLE decreases survival rates of SLE patients. Renal insufficiency and high disease activity are predictive of poor prognoses for NPSLE patients.CONCLUSIONSHigh disease activity and positive rate of anti-ribosomal P protein antibodies may be risk factors for NPSLE. NPSLE decreases survival rates of SLE patients. Renal insufficiency and high disease activity are predictive of poor prognoses for NPSLE patients. |
| Audience | Academic |
| Author | Wang, Ziqian Zhang, Shangzhu Li, Mengtao Li, Meng Zhang, Li You, Hui Zeng, Xiaofeng Wang, Qiang Wang, Yanhong |
| AuthorAffiliation | 3 Department of Epidemiology and Biostatistics (YW), Institute of Basic Medical Sciences, Peking Union Medical College & China Academy of Medical Sciences, Beijing 100730, China 1 Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, No. 1 Shuaifuyuan, Beijing 100730, China 2 Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Beijing 100730, China |
| AuthorAffiliation_xml | – name: 2 Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Beijing 100730, China – name: 3 Department of Epidemiology and Biostatistics (YW), Institute of Basic Medical Sciences, Peking Union Medical College & China Academy of Medical Sciences, Beijing 100730, China – name: 1 Department of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, No. 1 Shuaifuyuan, Beijing 100730, China |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33532504$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_3389_fpsyt_2023_1189940 crossref_primary_10_7759_cureus_53142 crossref_primary_10_1080_1744666X_2023_2260098 crossref_primary_10_3389_fimmu_2023_1122629 crossref_primary_10_1080_08820139_2024_2309567 crossref_primary_10_3389_fphar_2023_1207385 crossref_primary_10_33920_med_01_2410_04 crossref_primary_10_3389_fmed_2021_772607 |
| Cites_doi | 10.1080/1744666X.2019.1564040 10.1080/14397595.2016.1193966 10.1016/S1474-4422(13)70124-8 10.1002/art.1780350606 10.1002/art.1780400928 10.1002/art.34473 10.1177/0961203318772021 10.1177/0961203317722846 10.1016/j.berh.2005.04.003 10.1177/0961203308093829 10.2215/CJN.05780616 10.1177/0961203306070990 10.1007/s10067-017-3891-3 10.1002/art.23399 10.1016/j.clim.2016.08.019 10.1002/1529-0131(199904)42:4<599::aid-anr2>3.0.co;2-f 10.1177/0961203317691373 10.3899/jrheum.150135 10.1007/s10165-005-0411-0 10.1097/WCO.0000000000000554 10.1093/qjmed/93.3.169 10.1177/0961203313512540 10.1159/000485136 10.1212/01.wnl.0000144178.32208.4f 10.1177/0961203318792352 10.1177/0961203319860579 10.1177/0961203310388447 10.1038/nature22821 10.1016/j.berh.2010.10.006 10.1093/rheumatology/41.6.619 10.1136/annrheumdis-2011-201089 10.1002/art.39111 10.1136/annrheumdis-2012-202369 10.1136/lupus-2018-000281 10.1016/j.jaut.2008.12.002 10.1093/rheumatology/keu384 10.1371/journal.pone.0119911 10.1080/14397595.2019.1589912 10.1016/j.autrev.2020.102463 10.1186/s13075-017-1500-0 10.1038/s41584-018-0156-8 10.1016/j.autrev.2013.07.004 10.1016/j.autrev.2014.11.001 10.1177/0961203316666961 10.1016/j.semarthrit.2010.08.001 10.1038/nrneurol.2014.148 10.1136/ard.2008.106351 |
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| Copyright | Copyright © 2021 Shangzhu Zhang et al. COPYRIGHT 2021 John Wiley & Sons, Inc. Copyright © 2021 Shangzhu Zhang et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0 Copyright © 2021 Shangzhu Zhang et al. 2021 |
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| References | 44 46 47 48 49 Headache Classification Committee of the International Headache Society (12) 1988; 8 50 10 11 14 15 16 17 18 19 M. Feng (45) 2014; 19 1 2 3 4 5 6 7 8 9 20 21 22 23 24 25 26 27 28 29 A. Gmitrowicz (13) 1994; 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 |
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| Snippet | Objective. To identify the clinical characteristics, magnetic resonance imaging (MRI) results, and prognostic factors of neuropsychiatric (NP) systemic lupus... To identify the clinical characteristics, magnetic resonance imaging (MRI) results, and prognostic factors of neuropsychiatric (NP) systemic lupus... |
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| SubjectTerms | Adult Age Antibodies Anxiety disorders Biomarkers Blood circulation disorders Cerebrovascular disease China - epidemiology Comparative analysis Convulsions & seizures Creatinine Data collection Emotional disorders Female Headaches Humans Hypocomplementemia Immunology Inflammation Kaplan-Meier Estimate Laboratories Lupus Lupus Vasculitis, Central Nervous System - diagnosis Lupus Vasculitis, Central Nervous System - epidemiology Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medical colleges Medical prognosis Mood disorders Nervous system Neuroimaging - methods Neurological complications Patient Outcome Assessment Patient outcomes Patients Phenotype Prognosis Proportional Hazards Models Proteins Psychosis Public Health Surveillance Renal insufficiency Risk factors Seizures (Medicine) Severity of Illness Index Skull Survival Symptom Assessment Systemic lupus erythematosus Vascular diseases Viral antibodies Young Adult |
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| Title | Clinical Features and Outcomes of Neuropsychiatric Systemic Lupus Erythematosus in China |
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